Product image of Naproxen Chelonia Healthcare (Naproxen Bp) supplied by GNH India

Naproxen Chelonia Healthcare

Active Ingredient:
Naproxen Bp
Origin:
EU

Naproxen Chelonia Healthcare (Naproxen Bp)

Naproxen, the active ingredient in Naproxen Chelonia Healthcare, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a standard‑strength oral tablet for oral use. It relieves mild to moderate pain, reduces inflammation, and helps manage arthritis, dysmenorrhea, and fever in adults.

GNH India supplies Naproxen Chelonia Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Chelonia Healthcare Limited

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Indications & Clinical Uses

Naproxen acts on inflammatory pathways to provide analgesic and antipyretic effects.

  • Mild to moderate pain: alleviates headache, dental, musculoskeletal and postoperative discomfort.
  • Inflammatory conditions: reduces swelling and stiffness in osteoarthritis and rheumatoid arthritis.
  • Dysmenorrhea: eases menstrual cramps and associated pelvic pain.
  • Fever: lowers elevated body temperature in acute febrile states.
  • Arthritis: improves joint function and comfort in chronic arthritic diseases.

How It Works

  • Naproxen reversibly inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The resulting reduction in prostaglandin synthesis diminishes peripheral sensitisation, inflammation, and the hypothalamic set‑point for temperature, thereby providing analgesic, anti‑inflammatory, and antipyretic actions.

Side Effects

Common Side Effects

  • Gastro‑intestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash: mild erythema or pruritus.

Serious or Rare Side Effects

  • Gastro‑intestinal ulceration or bleeding.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome).
  • Renal impairment or acute kidney injury.
  • Hepatic dysfunction with elevated transaminases.
  • Anaphylactic or severe hypersensitivity reactions.

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess renal function: monitor kidney parameters in patients with existing impairment.
  • Evaluate cardiovascular risk: use cautiously in individuals with heart disease or hypertension.
  • Review gastrointestinal history: avoid in active ulcer disease or recent GI bleeding.
  • Check concomitant medications: be vigilant when combined with other NSAIDs, anticoagulants or corticosteroids.
  • Store at ambient temperature: keep below 25°C in the original packaging, protect from moisture.

Avoid Interactions

Naproxen may interact with several medicines; awareness helps minimise risk.

Major Interactions (Avoid)

  • Warfarin or other anticoagulants: increased risk of bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs): additive gastrointestinal bleeding risk.
  • Lithium: naproxen can raise lithium serum concentrations.

Moderate Interactions (Monitor Closely)

  • Diuretics: may reduce renal clearance of naproxen.
  • Methotrexate: potential for reduced elimination and toxicity.

Frequently Asked Questions

Naproxen Chelonia Healthcare is indicated for the relief of mild to moderate pain, reduction of inflammation, management of arthritis symptoms, treatment of dysmenorrhea (menstrual cramps), and lowering of fever. It is commonly prescribed for musculoskeletal discomfort, joint disorders, and acute febrile episodes.

Naproxen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 (COX‑1/COX‑2) enzymes. This inhibition reduces the synthesis of prostaglandins, which are mediators of pain, inflammation, and fever. Lower prostaglandin levels lead to decreased sensitisation of nerve endings and reduced inflammatory swelling.

The specific dose of Naproxen Chelonia Healthcare is determined by the prescribing clinician based on the patient’s condition, age, weight, and overall health status. Healthcare professionals tailor the regimen to achieve optimal pain control while minimising potential risks.

Safety of naproxen in pregnancy and lactation depends on the trimester and clinical judgement. Generally, it is avoided in the third trimester because of potential fetal cardiovascular effects. Breastfeeding mothers should consult a healthcare provider, as naproxen can be excreted in small amounts in milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Both naproxen and ibuprofen belong to the NSAID class and share similar mechanisms of COX inhibition. Naproxen has a longer half‑life, often allowing twice‑daily dosing, whereas ibuprofen typically requires three‑to‑four doses per day. Choice between them depends on patient tolerance, dosing convenience, and specific risk‑benefit considerations.

Naproxen Chelonia Healthcare should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed until use.

The medication is taken orally, usually with a full glass of water. It can be taken with or without food; however, taking it with food or milk may reduce gastrointestinal discomfort. Patients should follow the prescribing clinician’s instructions regarding timing and frequency.

Serious risks include gastrointestinal ulceration or bleeding, cardiovascular events such as heart attack or stroke, severe skin reactions (e.g., Stevens‑Johnson syndrome), and renal impairment. Patients should seek immediate medical attention if they experience signs of bleeding, chest pain, sudden weakness, or severe skin rash.

Naproxen is contraindicated in individuals with known hypersensitivity to naproxen or other NSAIDs, active gastrointestinal ulcer disease, severe heart failure, or those who have had recent coronary artery bypass graft surgery. It should also be avoided in patients with significant renal or hepatic impairment unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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