Product image of Naproxen Crescent (Naproxen) supplied by GNH India

Naproxen Crescent

Active Ingredient:
Naproxen
Origin:
EU

Naproxen Crescent (Naproxen)

Naproxen, the active ingredient in Naproxen Crescent, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is used to relieve pain, reduce inflammation, and lower fever in adults and children when appropriate.

GNH India supplies Naproxen Crescent as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides regulatory documentation to support global distribution.

Manufacturer / TM Owner

Crescent Pharma International Limited

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Indications & Clinical Uses

Naproxen is an NSAID that reduces inflammation and pain through cyclooxygenase inhibition.

  • Pain: Provides relief from mild to moderate pain such as headache, dental pain, or musculoskeletal discomfort.
  • Inflammation: Decreases swelling and tenderness associated with conditions like sprains or soft‑tissue injuries.
  • Fever: Lowers elevated body temperature in febrile states.
  • Arthritis: Alleviates joint pain and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Naproxen inhibits both cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it diminishes inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Naproxen may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or heartburn.
  • Headache: mild to moderate intensity.
  • Dizziness: occasional sensation of light‑headedness.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Cardiovascular events such as myocardial infarction or stroke.
  • Severe skin reactions, including Stevens‑Johnson syndrome.
  • Hepatic enzyme elevation or liver injury.
  • Renal impairment or acute kidney injury.

Precautions & Warnings

When using Naproxen, consider the following safety measures.

  • Assess renal function: adjust use in patients with kidney impairment.
  • Monitor gastrointestinal risk: avoid in individuals with a history of ulcers or bleeding.
  • Avoid concurrent anticoagulants: increased risk of bleeding.
  • Use caution in cardiovascular disease: potential for adverse cardiac events.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Naproxen can interact with several medicines, requiring attention to avoid harmful effects.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Corticosteroids: additive ulcer risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may reduce antihypertensive effect.
  • Methotrexate: decreased renal clearance, possible toxicity.

Frequently Asked Questions

Naproxen Crescent contains naproxen, an NSAID that is commonly prescribed to relieve mild to moderate pain, reduce inflammation, and lower fever. It is indicated for conditions such as headache, dental pain, musculoskeletal discomfort, and various forms of arthritis.

Naproxen works by inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins. By lowering prostaglandin levels, it reduces the inflammatory response, diminishes pain signals, and helps control fever.

The appropriate dose of Naproxen Crescent is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and overall health status. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of naproxen in pregnancy and lactation depends on the trimester and individual risk factors. Generally, it is avoided in the third trimester and used with caution earlier. Breastfeeding mothers should consult their physician, as naproxen can be excreted in milk.

To order Naproxen Crescent, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Naproxen has a longer half‑life than many NSAIDs such as ibuprofen, allowing for less frequent dosing. Its anti‑inflammatory potency is comparable to diclofenac, but the safety profile regarding gastrointestinal and cardiovascular risk must be evaluated individually for each patient.

Naproxen Crescent should be stored at room temperature, below 25 °C. Keep the tablets in the original container, protect them from moisture and direct sunlight, and ensure the packaging remains tightly closed until use.

Naproxen Crescent is taken orally with a full glass of water. It may be taken with food or milk to lessen stomach irritation, unless the prescriber advises otherwise. Swallow the tablet whole; do not crush or chew unless instructed.

Serious risks include gastrointestinal bleeding or ulceration, cardiovascular events such as heart attack or stroke, severe skin reactions, liver injury, and acute kidney damage. Patients should seek immediate medical attention if they experience signs like black stools, chest pain, rash, or sudden swelling.

Individuals with a known hypersensitivity to naproxen or other NSAIDs, active peptic ulcer disease, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment should avoid Naproxen Crescent unless a physician determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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