Product image of Naproxen Evolan (Naproxen) supplied by GNH India

Naproxen Evolan

Active Ingredient:
Naproxen
Origin:
EU

Naproxen Evolan (Naproxen)

Naproxen, the active ingredient in Naproxen Evolan, is a nonsteroidal anti‑inflammatory drug presented as an oral tablet for oral use. It treats mild to moderate pain, inflammatory joint conditions and musculoskeletal discomfort in adults.
GNH India supplies Naproxen Evolan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Evolan Pharma Ab

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Indications & Clinical Uses

Naproxen Evolan is an NSAID that reduces inflammation and pain in several common conditions.

  • Mild to moderate pain: provides analgesia for headache, toothache, or postoperative discomfort.
  • Osteoarthritis: helps relieve joint pain and improves functional ability.
  • Rheumatoid arthritis: reduces inflammatory swelling and joint tenderness.
  • Musculoskeletal pain: eases strain, sprain and back‑ache symptoms.
  • Dysmenorrhea: lessens menstrual cramps and associated discomfort.

How It Works

  • Naproxen Evolan exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes. This inhibition decreases the conversion of arachidonic acid to prostaglandins, thereby reducing inflammation, pain signaling, and fever generation at the site of tissue injury.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Elevated blood pressure.
  • Skin rash or mild itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe renal impairment.
  • Hepatotoxicity with elevated liver enzymes.
  • Anaphylactic or severe allergic reactions.
  • Cardiovascular events such as myocardial infarction or stroke.

Precautions & Warnings

Before prescribing Naproxen Evolan, consider the following safety measures.

  • Cardiovascular risk: avoid in patients with recent heart attack or uncontrolled hypertension.
  • Gastrointestinal history: use cautiously in those with ulcer disease or bleeding disorders.
  • Renal function: monitor kidney function in patients with chronic kidney disease.
  • Hepatic impairment: adjust use in individuals with liver disease.
  • Pregnancy and lactation: assess risk‑benefit; generally avoid in the third trimester.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Naproxen Evolan can alter the activity of several concomitant medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): amplified bleeding risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal perfusion, monitor kidney function.
  • Diuretics: potential for reduced efficacy and renal effects.
  • Lithium: NSAIDs can raise lithium levels, requiring serum monitoring.

Frequently Asked Questions

Naproxen Evolan is indicated for the relief of mild to moderate pain, such as headaches or dental pain, and for inflammatory conditions including osteoarthritis, rheumatoid arthritis, musculoskeletal pain, and dysmenorrhea. It helps reduce pain intensity and improve functional ability in these disorders.

Naproxen works by blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins. By lowering prostaglandin levels, it diminishes inflammation, pain signaling, and fever responses at the site of injury or disease.

The specific dosage of Naproxen Evolan is determined by the prescribing healthcare professional based on the individual’s condition, severity, age, and other medical factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of naproxen during pregnancy and lactation depends on the trimester and clinical circumstances. It is generally avoided in the third trimester due to potential fetal risks, and caution is advised during early pregnancy and while breastfeeding. Consultation with a healthcare provider is essential before use.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Naproxen Evolan shares the core anti‑inflammatory and analgesic properties of other NSAIDs but has a relatively longer half‑life, allowing for less frequent dosing in many cases. Compared with ibuprofen, it may provide more sustained pain control, while the safety profile regarding gastrointestinal and cardiovascular risks is similar across the class.

Naproxen Evolan should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture, heat and direct sunlight, and ensure the packaging remains tightly closed until use.

Naproxen Evolan is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort. Patients should swallow the tablet whole and not crush or chew it unless directed by a healthcare professional.

The most serious risks include gastrointestinal bleeding or ulceration, cardiovascular events such as heart attack or stroke, severe renal impairment, and rare but severe allergic reactions like anaphylaxis. Patients should be monitored for signs of these conditions and seek immediate medical attention if they occur.

Individuals with a known hypersensitivity to naproxen or other NSAIDs, those with active gastrointestinal ulceration or bleeding, patients with severe heart failure, recent myocardial infarction, or uncontrolled hypertension should avoid Naproxen Evolan. Pregnant women in the third trimester and patients with significant renal or hepatic impairment should also refrain unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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