Product image of Naproxen Hasco (Naproxen) supplied by GNH India

Naproxen Hasco

Active Ingredient:
Naproxen
Origin:
EU

Naproxen Hasco (Naproxen)

Naproxen, the active ingredient in Naproxen Hasco, is a nonsteroidal anti-inflammatory drug (NSAID) presented as a suppository for rectal use. It treats pain and inflammation in conditions such as osteoarthritis, rheumatoid arthritis and dysmenorrhea.

GNH India supplies Naproxen Hasco as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hasco-Lek

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Indications & Clinical Uses

Naproxen is an NSAID that reduces inflammation and pain in several musculoskeletal and gynecologic conditions.

  • Osteoarthritis: alleviates joint pain and improves mobility.
  • Rheumatoid arthritis: decreases joint inflammation and stiffness.
  • Dysmenorrhea: relieves menstrual cramps and associated discomfort.
  • Acute pain: provides short‑term relief for mild to moderate pain episodes.

How It Works

  • Naproxen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which reduces the conversion of arachidonic acid to prostaglandins. Lower prostaglandin levels diminish inflammation, pain signaling, and fever responses in affected tissues.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Dyspepsia: indigestion or heartburn.
  • Abdominal pain: cramping or discomfort.
  • Headache: transient pressure sensation.
  • Dizziness: light‑headed feeling.
  • Diarrhea: loose stools.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Renal impairment or failure.
  • Cardiovascular events such as myocardial infarction.
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome).
  • Hepatic dysfunction or elevated liver enzymes.
  • Anaphylaxis: rare allergic shock.

Precautions & Warnings

Before using Naproxen, consider the following safety measures.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding.
  • Monitor renal function: especially in patients with kidney disease.
  • Evaluate cardiovascular risk: avoid in uncontrolled hypertension.
  • Use lowest effective dose: limit duration to the shortest necessary.
  • Avoid in known hypersensitivity: discontinue if allergic reaction occurs.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Naproxen can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding potential.
  • ACE inhibitors: possible reduction in renal function.
  • Lithium: elevated lithium serum levels.

Moderate Interactions (Monitor Closely)

  • Diuretics: risk of reduced renal perfusion.
  • Methotrexate: decreased clearance leading to toxicity.
  • Cyclosporine: enhanced nephrotoxic effect.
  • Beta‑blockers: potential attenuation of antihypertensive effect.
  • Corticosteroids: increased gastrointestinal ulcer risk.

Frequently Asked Questions

Naproxen Hasco is employed to relieve pain and reduce inflammation in musculoskeletal disorders such as osteoarthritis and rheumatoid arthritis, as well as in dysmenorrhea and other acute pain states. Its anti‑inflammatory action helps improve joint function and alleviate discomfort associated with these conditions.

Naproxen blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for producing prostaglandins. By lowering prostaglandin synthesis, naproxen diminishes the inflammatory response, reduces swelling, and interrupts pain signaling pathways, resulting in symptomatic relief.

The specific dose and dosing schedule for Naproxen Hasco are determined by the prescribing clinician based on the patient’s condition, severity, and individual health factors. Healthcare professionals tailor the regimen to achieve optimal therapeutic effect while minimizing risk.

Safety of naproxen during pregnancy or lactation has not been definitively established. It is generally advised to avoid NSAIDs in the third trimester and to discuss potential risks with a healthcare provider before use in pregnancy or while breastfeeding.

To request Naproxen Hasco, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Naproxen has a relatively long half‑life compared with ibuprofen or diclofenac, allowing for less frequent dosing. Its efficacy in reducing inflammation and pain is comparable, but individual tolerability and risk profiles (e.g., gastrointestinal or cardiovascular) may differ, so clinicians choose based on patient‑specific factors.

Naproxen Hasco suppositories should be stored at room temperature, below 25 °C, in the original packaging. Keep them away from moisture, direct sunlight, and extreme heat to maintain product stability and potency.

Naproxen Hasco is supplied as a rectal suppository. The suppository is inserted into the rectum according to the instructions provided by the prescriber, typically after a bowel movement and before lying down, to ensure optimal absorption.

Serious risks include gastrointestinal bleeding or ulceration, renal impairment, cardiovascular events such as heart attack or stroke, severe skin reactions, and hepatic dysfunction. Patients should be monitored for signs of these conditions, especially with prolonged use or high‑risk comorbidities.

Individuals with a known hypersensitivity to naproxen or other NSAIDs, active gastrointestinal ulceration, severe renal or hepatic disease, uncontrolled hypertension, or a history of cardiovascular thrombotic events should avoid using Naproxen Hasco unless directed by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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