Product image of Naproxen Infectopharm (Naproxen) supplied by GNH India

Naproxen Infectopharm

Active Ingredient:
Naproxen
Origin:
EU

Naproxen Infectopharm (Naproxen)

Naproxen, the active ingredient in Naproxen Infectopharm, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It relieves pain, reduces fever, and decreases inflammation in adults.

GNH India supplies Naproxen Infectopharm as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Infectopharm Arzneimittel Und Consilium Gmbh, De, Heppenheim

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Indications & Clinical Uses

Naproxen is an NSAID that acts on inflammatory pathways to manage several painful and febrile conditions.

  • Pain: Provides analgesic relief for mild to moderate acute or chronic pain.
  • Fever: Lowers elevated body temperature associated with infectious or inflammatory states.
  • Osteoarthritis: Reduces joint pain and stiffness, improving functional mobility.
  • Rheumatoid arthritis: Decreases synovial inflammation and joint discomfort.
  • Dysmenorrhea: Alleviates menstrual cramps and associated pelvic pain.
  • Inflammation: Controls swelling in musculoskeletal and soft‑tissue disorders.

How It Works

  • Naproxen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The reduction in prostaglandin synthesis diminishes peripheral sensitization, fever generation, and inflammatory exudate formation, resulting in analgesic, antipyretic, and anti‑inflammatory actions.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Nausea or upset stomach
  • Dyspepsia or heartburn
  • Headache
  • Dizziness
  • Mild rash or itching
  • Elevated blood pressure

Serious or Rare Side Effects

  • Gastrointestinal ulceration or bleeding
  • Cardiovascular events such as myocardial infarction or stroke
  • Acute renal impairment or failure
  • Severe skin reactions (e.g., Stevens‑Johnson syndrome)
  • Hepatic injury
  • Anaphylactic or severe allergic reactions

Precautions & Warnings

Before initiating therapy, consider the following safety measures.

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Evaluate cardiovascular profile: use the lowest effective dose in those with heart disease.
  • Monitor renal function: caution in patients with renal insufficiency or dehydration.
  • Use the lowest effective dose for the shortest duration needed.
  • Avoid in individuals with known hypersensitivity to naproxen or other NSAIDs.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Naproxen can alter the activity of several co‑administered medicines.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened chance of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • Diuretics: may reduce renal clearance of naproxen.
  • ACE inhibitors or ARBs: potential for reduced renal function.
  • Methotrexate: naproxen can raise methotrexate plasma levels, increasing toxicity.

Frequently Asked Questions

Naproxen Infectopharm is an oral NSAID indicated for the relief of mild to moderate pain, reduction of fever, and control of inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and dysmenorrhea. It is prescribed for adult patients who need anti‑inflammatory and analgesic therapy.

Naproxen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for prostaglandin synthesis. By lowering prostaglandin levels, it reduces peripheral sensitization, fever generation, and inflammatory exudate, providing analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Naproxen Infectopharm is determined by the prescribing healthcare professional based on the patient’s condition, severity, and individual risk factors. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Safety of naproxen in pregnancy and lactation has not been definitively established. It is generally avoided during the third trimester because of potential fetal cardiovascular effects, and caution is advised while breastfeeding. Pregnant or nursing patients should discuss alternatives with their healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Both naproxen and ibuprofen are NSAIDs that inhibit COX enzymes, but naproxen has a longer half‑life, allowing less frequent dosing, while ibuprofen is shorter‑acting. Naproxen may carry a slightly higher risk of cardiovascular events with long‑term use, whereas ibuprofen is often preferred for short‑term pain. Choice depends on clinical context and patient tolerance.

Store Naproxen Infectopharm at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight, and extreme heat. Do not store in the bathroom or near a kitchen sink where humidity is high.

Naproxen Infectopharm is taken orally, usually with a full glass of water. It can be taken with or without food, although a meal may reduce stomach irritation. The tablet (or capsule) should be swallowed whole and not crushed or chewed unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, cardiovascular events such as heart attack or stroke, acute kidney injury, severe skin reactions, and anaphylaxis. Patients should seek immediate medical attention if they notice black stools, sudden chest pain, shortness of breath, swelling, or a rash that spreads rapidly.

Naproxen Infectopharm should be avoided in individuals with known hypersensitivity to naproxen or other NSAIDs, active gastrointestinal ulcer or bleeding, severe heart failure, uncontrolled hypertension, and in the third trimester of pregnancy. Patients with significant renal or hepatic impairment should also consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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