Product image of Naproxeno Sódico Tad (Naproxen Sodium) supplied by GNH India

Naproxeno Sódico Tad

Active Ingredient:
Naproxen Sodium
Origin:
EU

Naproxeno Sódico Tad (Naproxen Sodium)

Naproxen, the active ingredient in Naproxeno Sódico Tad, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral dosage form for oral use. It is used to relieve mild to moderate pain, reduce inflammation, and lower fever in adults.
GNH India supplies Naproxeno Sódico Tad as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Tad Pharma Gmbh

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Indications & Clinical Uses

Naproxen sodium acts on inflammatory pathways to provide analgesic, antipyretic and anti‑inflammatory effects.

  • Mild to moderate pain: alleviates headache, dental pain, musculoskeletal aches, and postoperative discomfort.
  • Rheumatoid arthritis and osteoarthritis: reduces joint swelling, stiffness and functional limitation.
  • Dysmenorrhea: eases menstrual cramps and associated pelvic pain.
  • Fever: lowers elevated body temperature in acute febrile states.

How It Works

  • Naproxen sodium non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis diminishes peripheral sensitisation of nociceptors, lowers inflammatory exudate formation, and curtails the hypothalamic set‑point for temperature regulation, resulting in analgesic, anti‑inflammatory and antipyretic actions.

Side Effects

Adverse reactions may occur with naproxen sodium use and are categorised by frequency and severity.

Common Side Effects

  • Gastro‑intestinal upset (nausea, dyspepsia, abdominal pain)
  • Headache
  • Dizziness or light‑headedness
  • Mild rash or pruritus
  • Elevated liver enzymes (transient)

Serious or Rare Side Effects

  • Gastro‑intestinal bleeding or ulcer perforation
  • Cardiovascular events such as myocardial infarction or stroke
  • Severe skin reactions (Stevens‑Johnson syndrome, toxic epidermal necrolysis)
  • Acute renal failure or worsening of chronic kidney disease
  • Anaphylaxis or severe hypersensitivity reactions
  • Hepatotoxicity with jaundice

Precautions & Warnings

Before initiating therapy, clinicians should evaluate individual risk factors and monitor for potential complications.

  • Assess gastrointestinal risk: consider ulcer prophylaxis in patients with prior GI bleeding.
  • Monitor cardiovascular status: use lowest effective dose in patients with heart disease.
  • Use lowest effective dose for the shortest duration needed to control symptoms.
  • Avoid in patients with known hypersensitivity to naproxen or other NSAIDs.
  • Adjust dose cautiously in renal or hepatic impairment and monitor function.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Naproxen sodium can alter the pharmacokinetics or pharmacodynamics of several medicines, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): heightened bleeding tendency.

Moderate Interactions (Monitor Closely):\n- Diuretics: possible reduction in renal perfusion, monitor electrolytes.

  • Lithium: naproxen may raise lithium levels, requiring serum monitoring.
  • Methotrexate: decreased clearance may lead to toxicity, especially at high doses.

Frequently Asked Questions

Naproxeno Sódico Tad contains naproxen sodium, an NSAID indicated for mild to moderate pain, inflammatory joint disorders such as rheumatoid arthritis and osteoarthritis, dysmenorrhea (menstrual cramps), and fever. It helps reduce pain, swelling, and elevated body temperature in these conditions.

Naproxen sodium blocks the activity of cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are required for the production of prostaglandins. By lowering prostaglandin levels, it reduces inflammation, diminishes pain signalling, and resets the hypothalamic temperature set‑point, providing analgesic, anti‑inflammatory, and antipyretic effects.

The appropriate dose of Naproxeno Sódico Tad is determined by the prescribing healthcare professional based on the patient’s condition, age, renal and hepatic function, and other individual factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of naproxen sodium in pregnancy and lactation has not been definitively established. It is generally avoided in the third trimester because of potential fetal cardiovascular effects, and caution is advised during breastfeeding. Clinicians should weigh benefits against risks and consider alternative therapies when appropriate.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Naproxen has a longer half‑life than ibuprofen, allowing twice‑daily dosing for many patients, whereas ibuprofen often requires three‑four times daily. Both share similar efficacy for pain and inflammation, but naproxen may have a slightly higher risk of gastrointestinal irritation, while ibuprofen may be associated with a higher cardiovascular risk at high doses.

Naproxeno Sódico Tad should be stored at ambient temperature, below 25 °C (77 °F). Keep the product in its original packaging, protect it from moisture, heat and direct sunlight, and ensure the container is tightly closed to maintain stability.

The medication is taken orally, usually with a full glass of water. It may be taken with food or milk to lessen stomach upset, but should be swallowed whole and not crushed or chewed unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulcer perforation, cardiovascular events such as heart attack or stroke, severe skin reactions (e.g., Stevens‑Johnson syndrome), acute kidney injury, and hypersensitivity reactions including anaphylaxis. Patients should seek immediate medical attention if they experience signs of these conditions.

Individuals with a known allergy to naproxen or any NSAID, those with active gastrointestinal ulcers or bleeding, uncontrolled hypertension, severe heart failure, significant renal or hepatic impairment, and patients in the third trimester of pregnancy should not use Naproxeno Sódico Tad unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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