Naproxen Sodium Aurobindo (Naproxen Sodium)

Naproxen sodium exerts its effect by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the synthesis of prostaglandins. By lowering prostaglandin levels, the drug diminishes inflammation, pain signaling, and fever responses at the site of tissue injury or infection.

The specific dose of naproxen sodium is determined by the prescribing clinician based on the individual’s condition, age, renal function and other factors. Typical adult regimens range from 250 mg to 500 mg taken twice daily, but the exact amount and frequency must be set by a qualified healthcare professional.

Naproxen sodium is generally avoided during the third trimester of pregnancy because of potential risks to the fetus and prolonged labor. Use during the first two trimesters should only occur if the benefit outweighs the risk and under medical supervision. Limited data exist for breastfeeding, so a prescriber should evaluate safety before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details (including any temperature requirements) and assists with import documentation.

Both naproxen and ibuprofen belong to the NSAID class and share similar mechanisms of COX inhibition. Naproxen has a longer half‑life, allowing twice‑daily dosing, whereas ibuprofen often requires three‑four times daily. Naproxen may provide more sustained pain control for chronic conditions, but individual response and safety profiles should guide selection.

Store the product at room temperature, preferably below 25 °C, in its original packaging to protect it from moisture and excessive heat. Keep the container tightly closed and out of reach of children. Do not expose the tablets to direct sunlight or humid environments, as this may affect stability.

Naproxen sodium is taken orally with a full glass of water. It may be taken with food or milk to lessen gastrointestinal discomfort, but absorption is not significantly affected. Swallow the tablet whole; do not crush or chew unless specifically instructed by a healthcare professional.

The most serious adverse events include gastrointestinal ulceration or bleeding, severe renal impairment, cardiovascular events such as heart attack or stroke, and life‑threatening skin reactions like Stevens‑Johnson syndrome. Patients should be monitored for signs of these conditions, especially if they have pre‑existing risk factors.

Naproxen sodium is contraindicated in individuals with known hypersensitivity to naproxen or other NSAIDs, active gastrointestinal ulcer or bleeding, severe heart failure, and in the third trimester of pregnancy. Caution is also advised for patients with uncontrolled hypertension, significant renal or hepatic disease, and those taking anticoagulants without close medical supervision.