Product image of Naproxennatrium Liquid Caps Kruidvat (Naproxen Sodium) supplied by GNH India

Naproxennatrium Liquid Caps Kruidvat

Active Ingredient:
Naproxen Sodium
Origin:
EU

Naproxennatrium Liquid Caps Kruidvat (Naproxen Sodium)

Naproxen sodium, the active ingredient in Naproxennatrium Liquid Caps Kruidvat, is a nonsteroidal anti-inflammatory drug presented as a liquid capsule for oral use. It treats mild to moderate pain, inflammatory conditions such as osteoarthritis and rheumatoid arthritis, musculoskeletal pain, and dysmenorrhea in adults, providing short‑term relief of associated symptoms.

GNH India supplies Naproxennatrium Liquid Caps Kruidvat as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mae Holding Bv

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Indications & Clinical Uses

Naproxen sodium is an NSAID that reduces inflammation and pain in several musculoskeletal and gynecologic conditions.

  • Osteoarthritis: reduces joint pain and swelling.
  • Rheumatoid arthritis: alleviates inflammatory joint symptoms.
  • Musculoskeletal pain: provides analgesic relief for strains, sprains and back pain.
  • Dysmenorrhea: eases menstrual cramps and associated discomfort.

How It Works

  • Naproxen sodium exerts its effect by reversibly inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis diminishes inflammation, pain signaling, and fever generation at the site of tissue injury.

Side Effects

Naproxen sodium may cause a range of adverse reactions, from mild to serious.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Skin rash: mild erythema or itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer perforation.
  • Renal impairment: reduced kidney function or acute failure.
  • Severe skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Anaphylaxis: rapid onset of allergic symptoms requiring emergency care.

Precautions & Warnings

Before using Naproxen sodium, consider the following safety measures.

  • Assess renal function: avoid in patients with severe renal impairment.
  • Monitor gastrointestinal risk: use cautiously in individuals with a history of ulcers or bleeding.
  • Avoid concurrent anticoagulants: increased risk of hemorrhage.
  • Use caution in asthma: may precipitate bronchospasm.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Naproxen sodium can interact with several medicines; some require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Selective COX‑2 inhibitors: additive gastrointestinal toxicity.
  • High‑dose aspirin: enhanced renal toxicity.
  • Methotrexate: reduced clearance leading to toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: possible reduction in renal function.
  • Diuretics: heightened risk of renal impairment.
  • Lithium: increased serum lithium levels.

Frequently Asked Questions

Naproxennatrium Liquid Caps Kruidvat contains naproxen sodium, an NSAID indicated for the short‑term relief of mild to moderate pain, inflammation associated with osteoarthritis, rheumatoid arthritis, musculoskeletal injuries, and dysmenorrhea. It is prescribed for adults who need anti‑inflammatory and analgesic therapy.

Naproxen sodium works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish inflammation, pain signaling, and fever, providing therapeutic relief in conditions where these mediators are elevated.

The specific dose of Naproxennatrium Liquid Caps is determined by the prescribing clinician based on the patient’s condition, severity of symptoms, age, renal function and other individual factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety of naproxen sodium in pregnancy or lactation has not been definitively established. It is generally avoided in the third trimester because of potential fetal cardiovascular effects, and caution is advised during breastfeeding. Healthcare providers should evaluate risks versus benefits before prescribing.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Both naproxen and ibuprofen are NSAIDs that inhibit COX enzymes, but naproxen has a longer half‑life, allowing less frequent dosing, while ibuprofen may have a slightly faster onset. Their safety profiles are similar, though naproxen may carry a marginally higher risk of gastrointestinal irritation in long‑term use.

Naproxennatrium Liquid Caps should be stored at ambient temperature, preferably below 25 °C. Keep the capsules in the original packaging, protect them from moisture, direct sunlight and excessive heat to maintain product stability throughout its shelf life.

The capsules are intended for oral administration. They should be swallowed whole with a full glass of water, preferably with food or milk to reduce gastrointestinal discomfort, unless the prescriber provides alternative instructions.

Serious risks include gastrointestinal bleeding or ulcer perforation, severe renal impairment, cardiovascular events such as myocardial infarction or stroke, and rare but life‑threatening skin reactions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience symptoms such as black stools, sudden kidney problems, chest pain, or severe rash.

Naproxen sodium is contraindicated in individuals with known hypersensitivity to naproxen or other NSAIDs, active gastrointestinal ulceration or bleeding, severe heart failure, and those who have had a recent coronary artery bypass graft. It should also be used with caution in patients with asthma, renal or hepatic impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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