Product image of Naramig (Naratriptan) supplied by GNH India

Naramig

Active Ingredient:
Naratriptan
Origin:
EU

Naramig (Naratriptan)

Naratriptan, the active ingredient in Naramig, is a Triptan presented as an oral tablet for oral use. It is indicated for the acute treatment of migraine attacks in adults. By targeting specific serotonin receptors, it helps relieve headache pain and associated symptoms such as nausea, photophobia, and phonophobia.

GNH India supplies Naramig as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. Our quality‑assured manufacturing follows EU standards, ensuring consistent potency and safety for patients across global markets.

Manufacturer / TM Owner

Glaxosmithkline Oy

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Indications & Clinical Uses

  • Naratriptan is a Triptan used in the migraine pathway to treat acute migraine attacks.
  • Migraine: provides rapid relief of headache pain and associated symptoms during an acute migraine episode.
  • Migraine with aura: alleviates headache and visual disturbances that accompany aura phases.
  • Acute episodic migraine: reduces the severity and duration of single migraine attacks when taken at onset.

How It Works

  • Naratriptan acts as a selective agonist at 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve endings. Activation of these receptors causes vasoconstriction of dilated intracranial arteries and inhibits the release of pro‑inflammatory neuropeptides, thereby interrupting the migraine cascade and relieving pain.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Dizziness: transient light‑headedness.
  • Fatigue: feeling unusually tired.
  • Tingling or numbness: usually in extremities.
  • Dry mouth: reduced salivation.
  • Chest discomfort: mild pressure or tightness.

Serious or Rare Side Effects

  • Coronary artery spasm: severe chest pain requiring immediate attention.
  • Serotonin syndrome: agitation, hyperthermia, and neuromuscular abnormalities when combined with other serotonergic agents.
  • Severe hypertension: sudden rise in blood pressure.
  • Allergic reactions: rash, itching, swelling, or anaphylaxis.
  • Cardiac arrhythmias: irregular heart rhythms.
  • Myocardial infarction: rare heart attack events.

Precautions & Warnings

Before prescribing Naratriptan, consider the following precautions:

  • Cardiovascular assessment: evaluate history of heart disease, ischemia, or uncontrolled hypertension.
  • Drug interactions: avoid concomitant use with ergotamine or other triptans.
  • Age considerations: safety not fully established in elderly populations.
  • Pregnancy: use only if potential benefit justifies potential risk to the fetus.
  • Renal or hepatic impairment: dose adjustment may be required based on clinical judgment.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Naratriptan may interact with several medication classes.

Major Interactions (Avoid)

  • Ergot derivatives: combined use can cause severe vasospasm.
  • MAO inhibitors: increased risk of serotonin syndrome.
  • SSRIs, SNRIs, or other serotonergic agents: heightened serotonin toxicity.
  • Other triptans: additive vasoconstrictive effects.
  • Strong CYP1A2 inhibitors: may raise naratriptan plasma levels.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: possible additive blood pressure lowering.
  • Oral contraceptives: may affect efficacy of migraine control.
  • Antihistamines: could increase sedation.
  • Moderate CYP3A4 inhibitors: may modestly increase drug exposure.
  • NSAIDs: monitor for gastrointestinal irritation.

Frequently Asked Questions

Naramig contains naratriptan, a prescription medication used to treat acute migraine attacks in adults. It works to relieve headache pain and associated symptoms such as nausea, sensitivity to light, and sound when taken at the onset of a migraine episode.

Naratriptan selectively stimulates serotonin 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve endings. This causes vasoconstriction of dilated intracranial arteries and blocks the release of inflammatory neuropeptides, interrupting the migraine cascade.

The appropriate dose of Naramig is determined by a qualified prescriber based on the individual’s medical condition, response to therapy, and any concomitant medications. Patients should follow the dosing instructions provided by their healthcare professional.

Safety data for naratriptan in pregnancy and lactation are limited. It should only be used during pregnancy if the potential benefit justifies any potential risk to the fetus, and breastfeeding mothers should consult their physician before use.

To order Naramig, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Naramig (naratriptan) belongs to the triptan class, which is generally more specific for migraine relief than non‑specific analgesics. Compared with other triptans, naratriptan has a longer half‑life, offering extended migraine coverage, but individual response may vary.

Naramig tablets should be stored below 25 °C in a dry place, protected from moisture and light. Keep the product in its original packaging until use and discard any tablets that appear discolored or damaged.

Naramig is taken orally, usually as a single tablet at the first sign of a migraine attack. Patients should swallow the tablet whole with water and avoid crushing or chewing it. If needed, a second dose may be taken after a minimum interval as advised by a physician.

Serious risks include coronary artery spasm, myocardial infarction, severe hypertension, and serotonin syndrome, especially when combined with other serotonergic drugs. Patients should seek immediate medical attention if they experience chest pain, severe headache, or symptoms of serotonin excess.

Naramig is contraindicated in patients with a history of coronary artery disease, uncontrolled hypertension, severe hepatic or renal impairment, or those who have previously experienced an allergic reaction to naratriptan or any other triptan.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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