Product image of Naramig (Naratriptan) supplied by GNH India

Naramig

Active Ingredient:
Naratriptan
Origin:
EU

Naramig (Naratriptan)

Naratriptan, the active ingredient in Naramig, is a Triptan (selective 5‑HT1B/1D receptor agonist) presented as an oral tablet for oral use. It treats acute migraine attacks in adults, providing relief of headache and associated symptoms.

GNH India supplies Naramig as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glaxosmithkline Pharmaceuticals En Abrege Glaxosmithkline

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Indications & Clinical Uses

  • Naratriptan belongs to the triptan class and is used for the acute management of migraine.
  • Migraine attacks (with or without aura): provides rapid relief of headache and associated symptoms.
  • Acute migraine in adults: helps abort the migraine episode when taken at onset.
  • Migraine‑associated nausea: may alleviate nausea accompanying a migraine attack.

How It Works

  • Naratriptan acts as an agonist at serotonin 5‑HT1B and 5‑HT1D receptors located on cranial blood vessels and trigeminal nerve endings. Activation of these receptors causes vasoconstriction of intracranial arteries and inhibits the release of pro‑inflammatory neuropeptides, thereby reducing migraine pain and associated sensory disturbances.

Side Effects

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Dizziness: transient light‑headed sensation.
  • Fatigue: feeling of tiredness or reduced energy.
  • Dry mouth: reduced salivation.
  • Tingling: paresthesia in extremities.

Serious or Rare Side Effects

  • Chest pain: possible cardiac ischemia.
  • Serotonin syndrome: agitation, hyperthermia, muscle rigidity.
  • Severe hypertension: sudden rise in blood pressure.
  • Allergic reaction: rash, swelling, or anaphylaxis.
  • Vision changes: blurred vision or visual disturbances.

Precautions & Warnings

  • Before prescribing Naratriptan, clinicians should evaluate patient history and potential risk factors.
  • Assess cardiovascular risk: review history of coronary artery disease, stroke, or uncontrolled hypertension.
  • Avoid in uncontrolled hypertension: do not use if blood pressure is not adequately managed.
  • Screen for serotonin syndrome: consider concurrent serotonergic drugs.
  • Pregnancy and lactation: use only if benefits outweigh potential risks.
  • Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Avoid Interactions

Naratriptan may interact with several drug classes; careful review is recommended.

Major Interactions (Avoid)

  • MAO inhibitors: risk of severe hypertension and serotonin syndrome.
  • Other triptans: additive vasoconstrictive effect.
  • Ergot alkaloids: increased risk of vasospasm.
  • SSRIs/SNRIs: potential for serotonin syndrome.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: may enhance blood pressure lowering.
  • Oral contraceptives: possible reduced efficacy.
  • Antihistamines: may increase sedation.
  • CYP1A2 inhibitors: may raise naratriptan plasma levels.

Frequently Asked Questions

Naramig contains the active ingredient naratriptan and is indicated for the acute treatment of migraine attacks, with or without aura, in adult patients. It is taken at the first sign of a migraine to help stop the headache and relieve associated symptoms such as nausea and sensitivity to light.

Naratriptan works by stimulating serotonin 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve fibers. This causes the vessels to constrict and blocks the release of inflammatory neuropeptides, which together reduce the pain and other neurological symptoms of a migraine.

The specific dose of Naramig is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and other factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

The safety of naratriptan in pregnancy and lactation has not been fully established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity of Naramig. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Naramig (naratriptan) belongs to the triptan class, which is generally more specific for migraine relief than non‑specific analgesics such as NSAIDs. Compared with other triptans, naratriptan has a longer half‑life, which may provide sustained relief but can also be associated with a slightly higher incidence of certain side effects.

Naramig should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Naramig is taken orally, usually as a tablet, at the first sign of a migraine attack. It should be swallowed with a glass of water and not crushed or chewed unless otherwise directed by a healthcare professional.

Serious risks include chest pain or tightness that may indicate cardiac ischemia, serotonin syndrome when combined with other serotonergic agents, severe hypertension, and rare allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience any of these symptoms.

Naramig should be avoided in patients with uncontrolled hypertension, a history of coronary artery disease, stroke, or peripheral vascular disease, and in those taking MAO inhibitors, other triptans, or ergot derivatives. It is also contraindicated in individuals with known hypersensitivity to naratriptan or any of the tablet’s excipients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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