Product image of Naramig (Naratriptan) supplied by GNH India

Naramig

Active Ingredient:
Naratriptan
Origin:
EU

Naramig (Naratriptan)

Naratriptan, the active ingredient in Naramig, is a Triptan presented as a tablet for oral use. It is prescribed for the acute treatment of migraine attacks in adults, with or without aura.

GNH India supplies Naramig as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glaxosmithkline B.V.

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Indications & Clinical Uses

  • Naratriptan belongs to the Triptan class and is used to treat migraine episodes.
  • Migraine with aura: provides rapid relief of headache and associated symptoms.
  • Migraine without aura: reduces headache intensity and duration.
  • Acute migraine attacks: shortens the overall course of the migraine episode.

How It Works

  • Naratriptan acts as a selective agonist at serotonin 5‑HT1B and 5‑HT1D receptors located on intracranial blood vessels and trigeminal nerve terminals. Activation of these receptors causes cranial vasoconstriction and inhibits the release of pro‑inflammatory neuropeptides, thereby alleviating migraine pain and associated symptoms.

Side Effects

Common Side Effects

  • Nausea
  • Dizziness
  • Fatigue
  • Tingling or numbness (paresthesia)
  • Dry mouth
  • Drowsiness

Serious or Rare Side Effects

  • Chest pain or tightness
  • Coronary artery spasm
  • Serotonin syndrome
  • Severe allergic reaction (anaphylaxis)
  • Significant hypertension
  • Cardiac arrhythmias

Precautions & Warnings

Before using Naramig, consider the following precautions:

  • Cardiovascular disease: assess risk of ischemic heart disease.
  • Uncontrolled hypertension: avoid use in patients with high blood pressure.
  • History of coronary artery spasm: contraindicated.
  • Concomitant serotonergic agents: monitor for serotonin syndrome.
  • Severe hepatic impairment: use with caution.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Naratriptan may interact with several medicines.

Major Interactions (Avoid)

  • MAO inhibitors: increased risk of serotonin syndrome.
  • SSRIs, SNRIs, or other serotonergic drugs: risk of serotonin toxicity.
  • Ergot alkaloids: additive vasoconstrictive effects.
  • Other triptans: cumulative vasoconstriction.
  • Strong CYP1A2 inhibitors (e.g., fluvoxamine): may raise naratriptan levels.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: possible additive blood pressure effects.
  • Oral contraceptives: may alter efficacy.
  • Antihistamines: may increase sedation.
  • CYP2D6 inhibitors: modest increase in plasma concentration.
  • NSAIDs: monitor for gastrointestinal irritation.

Frequently Asked Questions

Naramig contains the active ingredient naratriptan and is used for the acute treatment of migraine attacks in adults, with or without aura. It helps relieve headache pain and associated migraine symptoms when taken at the onset of an episode.

Naratriptan works by selectively stimulating serotonin 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve endings. This causes vasoconstriction of dilated intracranial vessels and blocks the release of inflammatory neuropeptides, reducing migraine pain.

The appropriate dose of Naramig is determined by a qualified prescriber based on the individual patient's clinical condition, medical history, and response to therapy. Patients should follow the dosing instructions provided by their healthcare professional.

The safety of naratriptan in pregnancy and lactation has not been definitively established. Healthcare providers should weigh the potential benefits against possible risks before prescribing Naramig to pregnant or nursing women.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

Naramig (naratriptan) belongs to the triptan class, which is generally more specific for migraine relief than non‑specific analgesics. Compared with other triptans, naratriptan has a longer half‑life, offering extended migraine coverage, but individual response may vary.

Naramig tablets should be stored at ambient temperature, below 25 °C, in their original packaging. Protect the tablets from moisture and direct sunlight to maintain their stability and potency.

Naramig is taken orally as a tablet. The tablet should be swallowed whole with a glass of water, preferably at the first sign of a migraine attack, unless otherwise directed by a healthcare professional.

Serious risks include chest pain or tightness, coronary artery spasm, severe hypertension, cardiac arrhythmias, and serotonin syndrome, especially when combined with other serotonergic drugs. Patients should seek immediate medical attention if any of these symptoms occur.

Naramig should be avoided in patients with uncontrolled hypertension, a history of ischemic heart disease or coronary vasospasm, severe hepatic impairment, or in those taking MAO inhibitors or other serotonergic agents without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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