Product image of Naramig (Naratriptan) supplied by GNH India

Naramig

Active Ingredient:
Naratriptan
Origin:
EU

Naramig (Naratriptan)

Naratriptan, the active ingredient in Naramig, is a Triptan (5‑HT1B/1D receptor agonist) presented as an oral tablet for oral use. It is indicated for the acute treatment of migraine attacks in adults.

GNH India supplies Naramig as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glaxo Wellcome Farmacêutica, Lda

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Indications & Clinical Uses

  • Naratriptan belongs to the triptan class and is used to treat migraine episodes.
  • Migraine: provides rapid relief of headache pain and associated symptoms during an acute migraine attack.
  • Acute migraine: reduces the severity and duration of migraine when taken at the first sign of an attack.
  • Migraine with aura: alleviates headache and visual disturbances associated with migraine with aura.

How It Works

  • Naratriptan acts as a selective agonist at serotonin 5‑HT1B and 5‑HT1D receptors located on cranial blood vessels and trigeminal nerve endings. Activation of these receptors causes vasoconstriction of intracranial arteries and inhibits the release of pro‑inflammatory neuropeptides, thereby interrupting the migraine cascade and relieving headache pain.

Side Effects

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Dizziness: sensation of light‑headedness.
  • Fatigue: feeling unusually tired.
  • Dry mouth: reduced salivation.
  • Paresthesia: tingling sensations.
  • Somnolence: drowsiness.

Serious or Rare Side Effects

  • Chest pain: possible cardiac discomfort.
  • Arrhythmia: irregular heart rhythm.
  • Serotonin syndrome: agitation, hyperthermia, muscle rigidity.
  • Severe hypertension: sudden high blood pressure.
  • Allergic reaction: rash, swelling, breathing difficulty.
  • Ischemic events: rare stroke or myocardial infarction.

Precautions & Warnings

  • Before using Naramig, consider the following precautions.
  • Cardiovascular disease: avoid if you have coronary artery disease, angina, or history of myocardial infarction.
  • Uncontrolled hypertension: do not use in patients with severe high blood pressure.
  • Serotonergic drugs: caution when combined with SSRIs, SNRIs, or MAO inhibitors due to risk of serotonin syndrome.
  • Hemiplegic or basilar migraine: contraindicated in these rare migraine subtypes.
  • Elderly patients: use with caution, monitor for increased sensitivity to side effects.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Naratriptan may interact with several medications.

Major Interactions (Avoid)

  • MAO inhibitors: increase risk of serotonin syndrome.
  • Other triptans: additive vasoconstrictive effects.
  • Ergot alkaloids: heightened vasoconstriction and cardiovascular risk.
  • SSRIs/SNRIs: potential for serotonin syndrome.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: may enhance blood pressure lowering.
  • Oral contraceptives: possible reduced efficacy of migraine relief.
  • CYP1A2 inhibitors (e.g., fluvoxamine): may increase naratriptan plasma levels.
  • Antihistamines: may augment drowsiness.

Frequently Asked Questions

Naramig contains the active ingredient naratriptan and is prescribed for the acute treatment of migraine attacks in adults. It helps to relieve headache pain, nausea, and sensitivity to light or sound that occur during a migraine episode.

Naratriptan works by selectively stimulating serotonin 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve fibers. This causes the vessels to constrict and blocks the release of inflammatory neuropeptides, interrupting the migraine cascade and reducing pain.

The dose of Naramig is determined by the prescribing healthcare professional based on the individual’s medical condition, response to therapy, and other medications. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

The safety of naratriptan in pregnancy and lactation has not been fully established. Healthcare providers will weigh the potential benefits against possible risks before prescribing it to pregnant or nursing women. Patients should discuss their situation with a doctor.

To order Naramig, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Naramig (naratriptan) belongs to the triptan class, which is generally more effective for moderate to severe migraine than simple analgesics. Compared with other triptans, naratriptan has a longer half‑life, offering sustained relief but may have a slower onset of action.

Naramig tablets should be stored at room temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged.

Naramig is taken orally with a glass of water. It is usually taken at the first sign of a migraine attack. Patients should not exceed the maximum daily dose recommended by their prescriber.

Serious risks include chest pain or tightness, heart rhythm disturbances, severe hypertension, serotonin syndrome when combined with other serotonergic drugs, and rare allergic reactions. Any of these symptoms require immediate medical attention.

Naramig should not be used by individuals with a history of coronary artery disease, uncontrolled hypertension, hemiplegic or basilar migraine, or those taking MAO inhibitors or other triptans. Patients with known hypersensitivity to naratriptan should also avoid it.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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