Product image of Naramig (Naratriptan) supplied by GNH India

Naramig

Active Ingredient:
Naratriptan
Origin:
EU

Naramig (Naratriptan)

Naratriptan, the active ingredient in Naramig, is a serotonin 5‑HT1B/1D receptor agonist (triptan) presented as a tablet for oral use. It treats acute migraine attacks in adults, providing relief from headache pain and associated symptoms.

GNH India supplies Naramig as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glaxo S.A.

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Indications & Clinical Uses

Naratriptan is indicated for the acute treatment of migraine, a neurovascular headache disorder.

  • Migraine: alleviates headache pain and associated symptoms such as nausea, photophobia, and phonophobia.

How It Works

  • Naratriptan selectively binds to and activates 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve terminals. This activation causes vasoconstriction of dilated intracranial arteries and inhibits the release of vasoactive neuropeptides, thereby reducing neurogenic inflammation and interrupting migraine pain pathways.

Side Effects

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Dizziness: transient light‑headed sensation.
  • Fatigue: feeling unusually tired.
  • Dry mouth: reduced salivation.

Serious or Rare Side Effects

  • Chest pain: possible cardiac discomfort.
  • Severe hypertension: sudden high blood pressure.
  • Serotonin syndrome: agitation, hyperthermia, muscle rigidity.
  • Allergic reactions: rash, swelling, or anaphylaxis.

Precautions & Warnings

Before using Naramig, consider the following precautions.

  • Cardiovascular assessment: evaluate for coronary artery disease or uncontrolled hypertension.
  • Contraindication review: avoid in patients with a history of ischemic heart disease.
  • Drug interaction check: be cautious when combined with other serotonergic agents.
  • Pregnancy counseling: discuss potential risks with a healthcare professional.
  • Storage: keep at ambient temperature below 25 °C, in the original packaging, protected from moisture.

Avoid Interactions

Naratriptan may interact with several medication classes.

Major Interactions (Avoid)

  • MAO inhibitors: risk of severe hypertension.
  • SSRIs, SNRIs, or other triptans: potential serotonin syndrome.
  • Ergot derivatives: additive vasoconstrictive effects.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: possible reduction in blood pressure control.
  • CYP3A4 inhibitors (e.g., ketoconazole): increased naratriptan exposure.
  • Oral contraceptives: may alter hormonal balance, monitor for side effects.

Frequently Asked Questions

Naramig contains the active ingredient naratriptan and is used for the acute treatment of migraine attacks in adults. It helps relieve headache pain and associated symptoms such as nausea, sensitivity to light, and sound.

Naratriptan works by selectively activating serotonin 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve endings. This causes vasoconstriction of dilated vessels and blocks the release of neuropeptides that trigger migraine pain.

The specific dose of Naramig is determined by the prescribing healthcare professional based on the individual’s clinical condition, severity of migraine, and response to therapy. Patients should follow the prescriber’s instructions exactly.

The safety of naratriptan in pregnancy and lactation has not been fully established. Healthcare providers should weigh potential benefits against possible risks and discuss alternative options with pregnant or nursing patients.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Naramig (naratriptan) belongs to the triptan class, which is generally more migraine‑specific than non‑specific analgesics. Compared with sumatriptan, naratriptan has a longer half‑life, offering a more extended period of symptom relief, but individual response may vary.

Store Naramig tablets at room temperature below 25 °C, in the original blister pack, and protect them from moisture and direct sunlight. Keep the medication out of reach of children and do not use after the expiry date.

Naramig is taken orally as a tablet. The tablet should be swallowed whole with a glass of water, preferably at the first sign of a migraine attack. Patients should not crush, chew, or split the tablet unless directed by a healthcare professional.

Serious risks include chest pain or tightness, severe hypertension, and serotonin syndrome, especially when combined with other serotonergic drugs. Any sudden cardiovascular symptoms or signs of an allergic reaction require immediate medical attention.

Naramig should be avoided in patients with uncontrolled hypertension, a history of ischemic heart disease, severe hepatic impairment, or known hypersensitivity to naratriptan or any tablet excipients. It is also contraindicated when used with certain ergot or other triptan medications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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