Product image of Naramig (Naratriptan) supplied by GNH India

Naramig

Active Ingredient:
Naratriptan
Origin:
EU

Naramig (Naratriptan)

Naratriptan, the active ingredient in Naramig, is a Triptan presented as an oral tablet for oral use. It is used for the acute treatment of migraine attacks in adults.
GNH India supplies Naramig as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glaxosmithkline Ab

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Indications & Clinical Uses

Naratriptan belongs to the Triptan class and is indicated for acute migraine management.

  • Migraine (with aura): provides rapid relief of headache pain and associated symptoms.
  • Migraine (without aura): reduces severity and duration of migraine attacks.
  • Acute migraine attack: offers prompt alleviation of headache when taken at onset.

How It Works

  • Naratriptan acts as a selective agonist at 5‑HT1B and 5‑HT1D receptors located on cranial blood vessels and trigeminal nerve endings. Activation of these receptors induces vasoconstriction of intracranial arteries and inhibits release of pro‑inflammatory neuropeptides, thereby interrupting the pain signaling cascade responsible for migraine.

Side Effects

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Dizziness: transient feeling of light‑headedness.
  • Fatigue: unusual tiredness after dosing.
  • Dry mouth: reduced salivation.

Serious or Rare Side Effects

  • Chest pain: possible cardiac discomfort requiring immediate evaluation.
  • Serotonin syndrome: rare but severe condition when combined with serotonergic agents.
  • Severe hypertension: unexpected rise in blood pressure.

Precautions & Warnings

Before prescribing Naramig, consider the following precautions.

  • Assess cardiovascular risk: evaluate history of coronary artery disease or ischemic heart disease.
  • Avoid in uncontrolled hypertension: contraindicated in patients with severe high blood pressure.
  • Caution with other triptans: do not combine with other acute migraine agents of the same class.
  • Monitor for serotonin syndrome: especially when patients use SSRIs, SNRIs, or MAO inhibitors.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Naratriptan may interact with several medication classes.

Major Interactions (Avoid)

  • MAO inhibitors: increased risk of serotonin syndrome.
  • Ergotamine derivatives: additive vasoconstriction may cause coronary spasm.
  • Other triptans: combined use can lead to excessive vasoconstriction.

Moderate Interactions (Monitor Closely)

  • SSRIs/SNRIs: potential for serotonin syndrome, monitor symptoms.
  • Antihypertensives: may enhance blood‑pressure‑lowering effects.
  • CYP1A2 inhibitors: can raise naratriptan plasma concentrations, adjust therapy if needed.

Frequently Asked Questions

Naramig contains the active ingredient naratriptan and is prescribed for the acute treatment of migraine attacks in adults. It helps to relieve headache pain and associated symptoms when taken at the onset of a migraine episode.

Naratriptan selectively stimulates serotonin 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve fibers. This action causes vasoconstriction of dilated intracranial arteries and blocks the release of pain‑triggering neuropeptides, interrupting the migraine pain pathway.

The specific dose and dosing schedule for Naramig are determined by the prescribing healthcare professional based on the individual patient's condition, response, and medical history. Patients should follow the prescriber’s instructions and not alter the dose on their own.

The safety of naratriptan in pregnancy and lactation has not been fully established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To request Naramig, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Naramig (naratriptan) belongs to the triptan class, which is generally more specific for migraine relief than non‑specific analgesics. Compared with other triptans, naratriptan has a longer half‑life, offering sustained relief, but individual response varies and the choice depends on patient tolerance and physician assessment.

Naramig tablets should be stored at ambient temperature, below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use it after the expiry date printed on the packaging.

Naramig is taken orally, usually as a whole tablet with a glass of water. It should be taken as soon as migraine symptoms begin, and may be repeated after a minimum interval if needed, according to the prescriber’s guidance.

Serious risks include chest pain or tightness, which may indicate cardiac vasospasm, and serotonin syndrome, especially when combined with other serotonergic drugs. Patients should seek immediate medical attention if they experience these symptoms.

Naramig is contraindicated in patients with a history of coronary artery disease, uncontrolled hypertension, peripheral vascular disease, or those who have previously experienced an adverse reaction to any triptan. It should also be avoided in patients taking ergotamine derivatives or monoamine oxidase inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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