Product image of Naramig (Naratriptan) supplied by GNH India

Naramig

Active Ingredient:
Naratriptan
Origin:
EU

Naramig (Naratriptan)

Naratriptan, the active ingredient in Naramig, is a selective serotonin (5‑HT1) receptor agonist presented as an oral tablet for oral use. It is used for the acute treatment of migraine attacks in adults.

GNH India supplies Naramig as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Glaxo Wellcome Uk Limited

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Indications & Clinical Uses

Naratriptan belongs to the triptan class and is employed for migraine management.

  • Migraine attacks: provides rapid relief of headache and associated symptoms.
  • Migraine with aura: reduces pain intensity and duration.
  • Migraine without aura: alleviates headache and photophobia.

How It Works

  • Naratriptan acts as an agonist at 5‑HT1B and 5‑HT1D receptors located on intracranial blood vessels and trigeminal nerve terminals. Activation causes vasoconstriction of dilated cranial vessels and inhibits the release of pro‑inflammatory neuropeptides, thereby interrupting the migraine cascade and relieving pain.

Side Effects

Common side effects are generally mild and transient.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Dizziness: sensation of light‑headedness.
  • Fatigue: feeling unusually tired.
  • Dry mouth: reduced salivation.
  • Paresthesia: tingling sensations.
  • Somnolence: increased sleepiness.

Serious or Rare Side Effects

  • Chest pain: possible cardiac discomfort.
  • Arrhythmia: irregular heart rhythm.
  • Serotonin syndrome: agitation, hyperthermia, tremor.
  • Severe hypertension: sudden high blood pressure.
  • Allergic reaction: rash, swelling, difficulty breathing.
  • Ischemic events: rare stroke or myocardial infarction.

Precautions & Warnings

Before prescribing Naramig, clinicians should evaluate patient‑specific risk factors.

  • Cardiovascular assessment: review history of heart disease or uncontrolled hypertension.
  • Concomitant serotonergic drugs: avoid combined use with SSRIs, SNRIs, or MAO inhibitors.
  • Renal or hepatic impairment: adjust use based on organ function.
  • Pregnancy and lactation: safety not established; weigh benefits against risks.
  • Storage: Store at room temperature: keep in original container, protect from moisture.

Avoid Interactions

Naratriptan may interact with several medication classes.

Major Interactions (Avoid)

  • MAO inhibitors: risk of serotonin syndrome.
  • Other triptans or ergot alkaloids: increased vasoconstriction.
  • Linezolid: potential serotonergic toxicity.

Moderate Interactions (Monitor Closely)

  • Antihypertensives: possible additive blood pressure effects.
  • CYP1A2 inhibitors (e.g., fluvoxamine): may raise naratriptan levels.
  • Oral contraceptives: may alter efficacy of migraine relief.

Frequently Asked Questions

Naramig contains naratriptan, a triptan medication indicated for the acute treatment of migraine attacks. It helps relieve headache pain and associated symptoms such as nausea, photophobia, and phonophobia when taken at the onset of an attack.

Naratriptan works by stimulating 5‑HT1B and 5‑HT1D receptors on cranial blood vessels and trigeminal nerve endings. This causes vasoconstriction of dilated vessels and blocks the release of inflammatory neuropeptides, interrupting the migraine cascade and reducing pain.

The appropriate dose of Naramig is determined by the prescribing healthcare professional based on individual patient factors. Dosage instructions are provided on the prescription label and should be followed exactly as directed.

The safety of naratriptan in pregnancy and lactation has not been established. Healthcare providers should assess the potential benefits against possible risks before prescribing Naramig to pregnant or nursing individuals.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Naramig (naratriptan) is a selective serotonin 5‑HT1 receptor agonist, similar to other triptans such as sumatriptan or rizatriptan. Compared with some alternatives, naratriptan has a longer half‑life, which may provide sustained relief with fewer doses, but individual response varies.

Naramig should be stored at room temperature, below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Naramig is taken orally, usually as a tablet, at the first sign of a migraine attack. It should be swallowed with water and not crushed or chewed. Patients should follow the dosing instructions provided by their prescriber.

Serious risks include chest pain or tightness, arrhythmias, severe hypertension, serotonin syndrome, and rare ischemic events such as stroke or myocardial infarction. Patients experiencing any of these symptoms should seek immediate medical attention.

Naramig is contraindicated in patients with uncontrolled hypertension, known coronary artery disease, history of stroke or transient ischemic attack, and those taking MAO inhibitors or other serotonergic agents. It should also be avoided in individuals with known hypersensitivity to naratriptan.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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