Product image of Naratriptan Stada (Naratriptan) supplied by GNH India

Naratriptan Stada

Active Ingredient:
Naratriptan
Origin:
EU

Naratriptan Stada (Naratriptan)

Naratriptan, the active ingredient in Naratriptan Stada, is a Triptan presented as a tablet for oral use. It treats acute migraine attacks in adults, providing relief from headache pain and associated symptoms.

GNH India supplies Naratriptan Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stadapharm Gmbh

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Indications & Clinical Uses

  • Naratriptan is a Triptan indicated for the acute treatment of migraine attacks.
  • Migraine with aura: reduces headache intensity and associated neurological symptoms.
  • Migraine without aura: provides rapid relief of pain, nausea and photophobia.
  • Menstrual migraine: helps alleviate headache and related discomfort during menstrual cycles.

How It Works

  • Naratriptan selectively binds to 5‑HT1B and 5‑HT1D receptors on intracranial blood vessels and trigeminal nerve endings. Activation of these receptors causes cranial vasoconstriction and inhibits the release of vasoactive neuropeptides, thereby reducing neurogenic inflammation and interrupting pain transmission during a migraine attack.

Side Effects

Naratriptan may cause a range of adverse reactions, which are generally classified by frequency.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Dizziness: sensation of light‑headedness.
  • Fatigue: feeling of tiredness.
  • Dry mouth: reduced salivation.
  • Chest discomfort: mild pressure in the chest.
  • Tingling sensation: paresthesia in extremities.

Serious or Rare Side Effects

  • Coronary vasospasm: constriction of heart arteries that can cause chest pain.
  • Myocardial infarction: rare heart attack event.
  • Serotonin syndrome: potentially life‑threatening condition when combined with other serotonergic drugs.
  • Severe hypertension: sudden high blood pressure.
  • Allergic reactions: rash, swelling, or anaphylaxis.
  • Cardiac arrhythmias: irregular heart rhythm.

Precautions & Warnings

  • When prescribing Naratriptan, clinicians should consider several safety measures to minimize risk.
  • Assess cardiovascular risk: evaluate history of coronary artery disease before use.
  • Avoid in uncontrolled hypertension: monitor blood pressure and limit use.
  • Caution with serotonergic agents: assess potential for serotonin syndrome.
  • Limit dosing frequency: do not exceed one dose per migraine attack, maximum two doses per 24 hours.
  • Discontinue if severe adverse reactions occur: seek immediate medical attention.
  • Store at ambient temperature: keep in original packaging, protect from moisture and light.

Avoid Interactions

Naratriptan can interact with other medicines, affecting its safety and efficacy.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of severe serotonin syndrome.
  • Ergotamine or ergot derivatives: additive vasoconstriction may cause coronary events.
  • Other triptans: combined use can lead to excessive vasoconstriction.

Moderate Interactions (Monitor Closely)

  • Selective serotonin reuptake inhibitors (SSRIs) and serotonin‑norepinephrine reuptake inhibitors (SNRIs): monitor for serotonin syndrome.
  • CYP3A4 inhibitors (e.g., ketoconazole, erythromycin): may increase naratriptan plasma levels.
  • Antihypertensive agents: possible additive blood pressure lowering effect.

Frequently Asked Questions

Naratriptan Stada is prescribed for the acute treatment of migraine attacks. It helps relieve headache pain and associated symptoms such as nausea, photophobia, and phonophobia when a migraine episode begins.

Naratriptan works by selectively activating 5‑HT1B and 5‑HT1D serotonin receptors in the brain. This activation causes constriction of dilated cranial blood vessels and blocks the release of pain‑triggering neuropeptides, thereby reducing migraine pain.

The dose of naratriptan is determined by the prescribing clinician based on the patient’s medical condition and response. The prescriber selects the appropriate tablet strength and timing for each individual migraine attack.

Safety data for naratriptan in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Naratriptan has a longer half‑life than some triptans, which can provide extended migraine relief for certain patients. Its onset of action is comparable, but individual response varies, so clinicians may choose it based on efficacy, tolerability, and patient history.

Store tablets at ambient temperature, below 25 °C, in the original container. Keep them away from moisture, heat and direct sunlight. Do not use tablets that are discoloured or have broken packaging.

Naratriptan Stada is taken orally with a glass of water. The tablet is usually swallowed whole and can be taken with or without food, as directed by the prescribing physician.

Serious risks include coronary vasospasm, myocardial infarction, severe hypertension, serotonin syndrome when combined with other serotonergic drugs, and rare allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience chest pain, severe headache, or signs of an allergic reaction.

Naratriptan should be avoided in patients with uncontrolled hypertension, known coronary artery disease, a history of myocardial infarction, severe liver impairment, or those taking MAO inhibitors or other triptans. It is also contraindicated in individuals with known hypersensitivity to naratriptan.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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