Nasadur 0,5 Mg/Ml (Xylometazoline Hydrochloride)

Xylometazoline Hydrochloride is a topical nasal decongestant that reduces swelling of the nasal mucosa.

• Nasal congestion: provides rapid relief of blockage and improves airflow.
• Rhinitis: alleviates congestion associated with allergic or non‑allergic rhinitis.
• Common cold: reduces nasal stuffiness caused by viral upper‑respiratory infection.

• Xylometazoline Hydrochloride acts as a selective alpha‑adrenergic receptor agonist on the smooth muscle of nasal mucosal blood vessels. Activation causes vasoconstriction, which diminishes blood flow, reduces edema, and opens the nasal passages. The effect begins within minutes and typically lasts several hours, providing temporary relief of congestion without systemic absorption.

Adverse reactions may occur with nasal use of Xylometazoline Hydrochloride.

Common Side Effects

• Nasal irritation or burning sensation.
• Dryness of the nasal mucosa.
• Sneezing.
• Headache.
• Altered taste or bitter taste.
• Mild epistaxis.

Serious or Rare Side Effects

• Severe hypertension or hypertensive crisis.
• Cardiac arrhythmias.
• Nasal ulceration or perforation with prolonged use.
• Allergic reactions such as angioedema or anaphylaxis.
• Rebound congestion (rhinitis medicamentosa) after extended use.
• Vision changes due to increased intra‑ocular pressure.

Use Nasadur 0,5 Mg/Ml according to professional guidance and observe safety measures.

• Duration of use: limit to 3‑5 days to avoid rebound congestion.
• Contraindications: avoid in patients with uncontrolled hypertension, coronary artery disease, hyperthyroidism, glaucoma, or those taking MAO inhibitors.
• Pregnancy: safety not established; consult a healthcare professional before use.
• Pediatric use: follow age‑specific recommendations; generally not for children under 2 years.
• Drug interactions: do not combine with other nasal decongestants or systemic sympathomimetics.
• Store at room temperature: keep in the original container, protect from moisture and direct heat.

Xylometazoline Hydrochloride may interact with other medicines; consider the following.

Major Interactions (Avoid)

• Other topical nasal decongestants: risk of excessive vasoconstriction and rebound congestion.
• Monoamine oxidase inhibitors (MAOIs): potential hypertensive crisis.
• Systemic sympathomimetic agents (e.g., pseudoephedrine): enhanced cardiovascular effects.

Moderate Interactions (Monitor Closely):\n- Antihypertensive drugs: possible reduction in blood‑pressure‑lowering effect.

• Antidepressants affecting catecholamine levels: monitor blood pressure.
• Nasal antihistamine sprays: may increase local irritation.