Product image of Nasarox (Oxymetazoline Hydrochloride) supplied by GNH India

Nasarox

Active Ingredient:
Oxymetazoline Hydrochloride
Origin:
EU

Nasarox (Oxymetazoline Hydrochloride)

Oxymetazoline Hydrochloride, the active ingredient in Nasarox, is an alpha‑adrenergic agonist presented as a nasal spray for topical nasal use. It relieves nasal congestion caused by the common cold, sinusitis and allergic rhinitis in adults and children over the recommended age.
GNH India supplies Nasarox as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bayer Portugal Lda

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Indications & Clinical Uses

Nasarox, an alpha‑adrenergic agonist nasal decongestant, is used to alleviate congestion in several upper‑respiratory conditions.

  • Common cold: reduces nasal blockage and improves breathing.
  • Sinusitis: decreases mucosal swelling to ease sinus drainage.
  • Allergic rhinitis: alleviates congestion associated with allergic inflammation.

How It Works

  • Oxymetazoline Hydrochloride acts as a selective alpha‑adrenergic receptor agonist on the vascular smooth muscle of nasal mucosa. Stimulation of these receptors induces vasoconstriction, which diminishes blood flow, reduces edema, and opens the nasal passages, providing rapid relief of congestion.

Side Effects

Nasal decongestants may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Dryness of the nasal mucosa.
  • Sneezing or mild itching.
  • Headache.
  • Transient taste disturbance.
  • Rebound congestion with prolonged use.

Serious or Rare Side Effects

  • Elevated blood pressure.
  • Palpitations or tachycardia.
  • Severe nasal ulceration.
  • Allergic skin rash.
  • Hypertensive crisis (very rare).
  • Cardiac arrhythmias (rare).

Precautions & Warnings

Before using Nasarox, consider the following safety measures.

  • Do not exceed the recommended frequency: limit to one or two sprays per nostril every 12 hours.
  • Avoid use for more than three consecutive days to prevent rebound congestion.
  • Consult a healthcare professional if you are pregnant, planning pregnancy, or breastfeeding.
  • Use with caution in patients with hypertension, cardiovascular disease, diabetes, or thyroid disorders.
  • Do not use in children under six years of age unless directed by a physician.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Oxymetazoline may interact with other medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.
  • Concurrent use of other nasal decongestants: additive vasoconstriction may increase systemic effects.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: possible reduction in blood pressure control.
  • Beta‑blockers: may mask tachycardia symptoms.
  • Tricyclic antidepressants: potential for increased blood pressure.

Frequently Asked Questions

Nasarox is an over‑the‑counter nasal spray containing oxymetazoline hydrochloride. It is used to temporarily relieve nasal congestion caused by the common cold, sinusitis, and allergic rhinitis by narrowing the blood vessels in the nasal passages.

Oxymetazoline is a selective alpha‑adrenergic agonist. When applied to the nasal mucosa, it stimulates alpha receptors on blood vessels, causing vasoconstriction. This reduces swelling of the nasal lining, opens the airway, and provides rapid decongestion.

The appropriate dose of Nasarox is determined by a healthcare professional. Typically, the label advises one or two sprays per nostril every 12 hours, not exceeding three days of continuous use, but the exact regimen should follow the prescriber’s instructions.

Safety data for oxymetazoline in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should consult their physician before using Nasarox to weigh potential benefits against any possible risks.

To order Nasarox, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Nasarox’s active ingredient, oxymetazoline, provides rapid, long‑lasting vasoconstriction compared with older agents like phenylephrine. It is generally more effective for short‑term relief, but like all decongestants, it should not be used beyond three days to avoid rebound congestion.

Store Nasarox at room temperature, below 25 °C, in its original packaging. Keep the bottle tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

Nasarox is applied topically to each nostril using the spray pump. The user tilts the head slightly forward, inserts the tip into the nostril, and presses the pump to deliver the recommended number of sprays. Avoid blowing the nose immediately after use.

Serious risks, though rare, include significant elevation of blood pressure, cardiac arrhythmias, and severe nasal ulceration. Persistent or worsening symptoms such as headache, palpitations, or nasal bleeding should prompt immediate medical attention.

Nasarox should be avoided by individuals with known hypersensitivity to oxymetazoline or any formulation components, children under six years of age unless directed by a physician, and patients with severe hypertension, coronary artery disease, or uncontrolled thyroid disorders without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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