Nasasinuspray Sine Conservans (Xylometazoline Hydrochloride)

Xylometazoline is a selective alpha‑adrenergic agonist. By stimulating alpha receptors on the blood vessels of the nasal mucosa, it causes vasoconstriction, which reduces blood flow, edema, and mucus formation, thereby opening the nasal airway.

The exact dose is determined by the prescribing healthcare professional. Typically, the product is administered as one or two sprays into each nostril, not exceeding the recommended frequency or duration, which is usually limited to three days to avoid rebound congestion.

Safety data for Xylometazoline during pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Xylometazoline is similar in action to other topical decongestants such as oxymetazoline or phenylephrine, but it may have a slightly longer duration of effect. All share the risk of rebound congestion with prolonged use, so they should be limited to short‑term therapy.

Store the nasal spray at room temperature, away from direct sunlight and moisture. Keep it in the original packaging to protect the nozzle from contamination. Do not freeze the product, and ensure the cap is tightly closed when not in use.

The spray is applied directly into each nostril while the head is upright. Gently insert the nozzle into the nostril, press the pump to deliver the prescribed number of sprays, and then repeat in the other nostril if required. Avoid blowing the nose immediately after use.

Serious adverse events, though rare, include severe hypertension, cardiac arrhythmias, nasal ulceration, allergic reactions such as anaphylaxis, and rebound congestion (rhinitis medicamentosa) after prolonged use. Patients should seek medical attention if they experience any of these symptoms.

Individuals with known hypersensitivity to Xylometazoline or any component of the formulation should avoid the product. It is also contraindicated in patients with severe hypertension, coronary artery disease, or those taking monoamine oxidase inhibitors without medical supervision.