Product image of Nasen (Zolpidem Tartrate) supplied by GNH India

Nasen

Active Ingredient:
Zolpidem Tartrate
Origin:
EU

Nasen (Zolpidem Tartrate)

Zolpidem Tartrate, the active ingredient in Nasen, is an imidazopyridine presented as an oral tablet for oral use. It is indicated for the short‑term treatment of insomnia in adults, helping to initiate and maintain sleep. The medication works by modulating central nervous system activity to promote sleep onset and continuity.

GNH India supplies Nasen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams worldwide, with reliable logistics.

Manufacturer / TM Owner

Polfarmex S.A.

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Indications & Clinical Uses

Zolpidem Tartrate is a sedative/hypnotic that acts on the central nervous system to treat insomnia.

  • Insomnia (short‑term): improves sleep onset and duration in adults.
  • Difficulty falling asleep: helps patients initiate sleep more quickly.
  • Frequent nighttime awakenings: reduces the number of awakenings and supports sleep continuity.

How It Works

  • Zolpidem Tartrate binds selectively to the benzodiazepine site of the GABA_A receptor complex, acting as a positive allosteric modulator. This enhances the inhibitory effect of GABA, increasing chloride ion influx into neurons, which leads to reduced neuronal excitability and produces sedative and hypnotic effects that facilitate sleep.

Side Effects

Zolpidem Tartrate may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Drowsiness: feeling unusually sleepy during the day.
  • Dizziness: light‑headed sensation or loss of balance.
  • Headache: mild to moderate pain in the head.
  • Nausea: feeling of stomach upset.
  • Dry mouth: reduced salivation.
  • Amnesia: short‑term memory impairment.

Serious or Rare Side Effects

  • Complex sleep behaviors: activities such as sleepwalking, driving, or eating while not fully awake.
  • Allergic reactions: rash, swelling, or difficulty breathing indicating hypersensitivity.

Precautions & Warnings

When prescribing Zolpidem Tartrate, several safety considerations should be observed.

  • Assess sleep history: confirm short‑term insomnia before use.
  • Avoid alcohol: concurrent use can increase sedation.
  • Use lowest effective dose: minimize risk of dependence.
  • Monitor for complex sleep behaviors: report unusual activities during sleep.
  • Avoid operating machinery: impairment may persist into the next day.
  • Store at room temperature: keep in original container, protect from moisture.

Avoid Interactions

Zolpidem Tartrate can interact with other medicines, affecting its safety and efficacy.

Major Interactions (Avoid)

  • Other CNS depressants (e.g., benzodiazepines, opioids): risk of profound sedation.
  • Alcohol: additive CNS depression and increased drowsiness.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): may raise zolpidem plasma levels.

Moderate Interactions (Monitor Closely):\n- CYP3A4 inducers (e.g., rifampin, carbamazepine): may reduce zolpidem effectiveness.

  • Certain antidepressants (e.g., fluoxetine, sertraline): can increase sedative effect.
  • Antihistamines (e.g., diphenhydramine): may add to drowsiness.

Frequently Asked Questions

Nasen contains zolpidem tartrate, which is prescribed for the short‑term treatment of insomnia in adults. It helps patients fall asleep more quickly and maintain sleep throughout the night, addressing difficulties with sleep onset and frequent awakenings.

Zolpidem tartrate acts as a positive allosteric modulator at the benzodiazepine site of the GABA_A receptor complex. By enhancing GABA‑mediated chloride influx, it reduces neuronal excitability, producing a sedative‑hypnotic effect that facilitates the initiation and maintenance of sleep.

The appropriate dose of Nasen is determined by the prescribing clinician based on the patient’s age, health status, and response to therapy. Dosage instructions are provided on the prescription label and should be followed exactly as directed by the healthcare professional.

Safety of zolpidem tartrate in pregnancy or while breastfeeding has not been definitively established. Healthcare providers usually weigh potential benefits against possible risks and may recommend alternative treatments if safer options are available.

To order Nasen, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nasen (zolpidem tartrate) is a short‑acting hypnotic that typically produces rapid sleep onset with a lower risk of next‑day sedation compared with longer‑acting benzodiazepines. It is often preferred for brief, acute insomnia episodes, whereas other agents may be chosen for chronic insomnia or specific comorbid conditions.

Store Nasen at room temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure they are out of reach of children.

Nasen is taken orally, usually as a single dose right before bedtime. It should be swallowed whole with a glass of water and taken only when the patient can dedicate a full night (7–8 hours) to sleep.

Serious risks include complex sleep behaviors such as sleepwalking, driving, or eating while not fully awake, as well as rare allergic reactions that may cause rash, swelling, or breathing difficulties. Patients should seek immediate medical attention if these events occur.

Nasen should be avoided in individuals with known hypersensitivity to zolpidem or any component of the formulation, those with severe hepatic impairment, and patients with a history of complex sleep behaviors or substance dependence unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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