Product image of Nasic (Mometasone Furoate Monohydrate) supplied by GNH India

Nasic

Active Ingredient:
Mometasone Furoate Monohydrate
Origin:
EU

Nasic (Mometasone Furoate Monohydrate)

Mometasone furoate monohydrate, the active ingredient in Nasic, is a corticosteroid presented as a nasal spray for nasal use. It treats allergic rhinitis in adults and children.
GNH India supplies Nasic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cassella-Med Gmbh & Co. Kg

1
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Indications & Clinical Uses

  • Nasic is a nasal corticosteroid that acts on inflammatory pathways of the nasal mucosa.
  • Allergic rhinitis: reduces nasal congestion, itching and sneezing associated with seasonal or perennial allergies.
  • Seasonal allergic rhinitis: provides symptom relief during pollen seasons.
  • Perennial allergic rhinitis: controls year‑round nasal inflammation caused by indoor allergens.

How It Works

  • Mometasone furoate monohydrate binds to intracellular glucocorticoid receptors in nasal epithelial cells, modulating gene transcription to suppress pro‑inflammatory cytokines, chemokines, and adhesion molecules. This reduces vascular permeability, mucus production, and inflammatory cell infiltration, leading to decreased nasal swelling and symptom relief.

Side Effects

Nasic may cause local and systemic adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Dryness of the nasal mucosa.
  • Epistaxis (nosebleeds).
  • Headache.
  • Altered taste or throat irritation.

Serious or Rare Side Effects

  • Nasal septum perforation.
  • Fungal infection of the nasal passages.
  • Severe or persistent nosebleeds.
  • Visual disturbances or cataract formation with prolonged use.
  • Adrenal suppression when used at high doses over extended periods.

Precautions & Warnings

Before using Nasic, consider the following precautions.

  • Use as prescribed: follow the healthcare professional’s instructions regarding frequency and duration.
  • Avoid prolonged continuous use without medical review to reduce risk of systemic effects.
  • Monitor for signs of local infection or fungal growth in the nasal cavity.
  • Caution in patients with glaucoma, cataracts, or uncontrolled diabetes.
  • Pregnancy and lactation: safety not established; use only if benefit outweighs risk.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Nasic may interact with other medications that affect corticosteroid activity or increase infection risk.

Major Interactions (Avoid)

  • Concurrent systemic corticosteroids: may increase systemic glucocorticoid exposure.
  • Live vaccines: nasal steroids may diminish immune response.

Moderate Interactions (Monitor Closely)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole): could raise local steroid levels.
  • Antifungal azoles: may potentiate local immunosuppression.
  • Nasal decongestants: combined use may increase nasal irritation.

Frequently Asked Questions

Nasic is a nasal spray that contains mometasone furoate monohydrate, a corticosteroid indicated for the relief of symptoms associated with allergic rhinitis, including nasal congestion, itching, sneezing, and rhinorrhea.

Mometasone furoate monohydrate binds to glucocorticoid receptors in the nasal mucosa, inhibiting the release of inflammatory mediators such as cytokines and prostaglandins. This anti‑inflammatory action reduces swelling and mucus production, improving nasal airflow.

The prescribed dose of Nasic is determined by the treating clinician. Typically, one or two sprays per nostril once daily are used, but the exact regimen should follow the healthcare professional’s instructions.

Safety of Nasic during pregnancy or lactation has not been definitively established. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and always under medical supervision.

To order Nasic, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nasic (mometasone furoate) offers a high receptor affinity and a low systemic bioavailability, similar to other potent nasal steroids such as fluticasone propionate and budesonide. Clinical studies suggest comparable efficacy in symptom control, with a favorable safety profile when used as directed.

Store Nasic at room temperature, preferably below 25 °C. Keep the bottle in its original packaging, protect it from moisture and direct sunlight, and ensure the cap is tightly closed when not in use.

Before first use, prime the spray by pressing the actuator several times until a fine mist appears. Tilt the head slightly forward, insert the tip into a nostril, and gently squeeze one spray while breathing in through the nose. Repeat in the other nostril if prescribed.

Serious risks include nasal septum perforation, opportunistic fungal infections of the nasal passages, severe or persistent nosebleeds, and, with prolonged high‑dose use, possible adrenal suppression. Any unusual symptoms should be reported to a healthcare professional promptly.

Nasic should be avoided in individuals with known hypersensitivity to mometasone or any component of the formulation, those with recent nasal surgery or trauma, and patients with active untreated nasal infections. Consultation with a clinician is essential before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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