Product image of Nasic Pur (Xylometazoline Hydrochloride, Dexpanthenol) supplied by GNH India

Nasic Pur

Active Ingredient:
Xylometazoline Hydrochloride, Dexpanthenol
Origin:
EU

Nasic Pur (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline Hydrochloride, the active ingredient in Nasic Pur, is a nasal decongestant (imidazoline derivative) presented as a nasal spray formulation for nasal use. It reduces nasal congestion associated with the common cold, sinusitis and allergic rhinitis in adults and children.

GNH India supplies Nasic Pur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution across EU and other global markets. The product conforms to EU quality standards and is manufactured under GMP conditions.

Manufacturer / TM Owner

Cassella-Med Gmbh & Co. Kg

1
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Indications & Clinical Uses

Nasic Pur, containing xylometazoline, acts on the nasal mucosa to relieve congestion in several common upper‑respiratory conditions.

  • Common cold: alleviates nasal blockage and improves breathing.
  • Sinusitis: reduces mucosal swelling to facilitate sinus drainage.
  • Allergic rhinitis: diminishes nasal congestion caused by allergen exposure.

How It Works

  • Xylometazoline Hydrochloride acts as an α‑adrenergic agonist, binding to α1‑adrenergic receptors on the vascular smooth muscle of the nasal mucosa. This induces vasoconstriction, decreasing blood flow and edema, which opens the nasal passages. Dexpanthenol, a provitamin B5 derivative, supports epithelial cell regeneration and provides moisturisation, helping to maintain mucosal integrity during treatment.

Side Effects

Nasic Pur may cause local and systemic adverse reactions, which are categorized by frequency.

Common Side Effects

  • Nasal burning or stinging sensation.
  • Mild nasal dryness or irritation.
  • Sneezing shortly after application.
  • Transient headache.
  • Unpleasant taste.
  • Epistaxis (minor nosebleed).

Serious or Rare Side Effects

  • Rebound nasal congestion (rhinitis medicamentosa) with prolonged use.
  • Elevated blood pressure or tachycardia.
  • Severe allergic reaction (anaphylaxis, angioedema).
  • Nasal ulceration or perforation.
  • Persistent nasal irritation requiring medical attention.

Precautions & Warnings

Before using Nasic Pur, consider the following precautions to ensure safe and effective treatment.

  • Duration of use: limit to no more than 3‑5 consecutive days to avoid rebound congestion.
  • Age restriction: avoid in children under 6 years unless advised by a physician.
  • Pregnancy and lactation: consult a healthcare professional before use, as safety data are limited.
  • Cardiovascular conditions: use with caution in patients with hypertension or heart disease.
  • Concomitant decongestants: do not combine with other nasal or oral decongestants without medical guidance.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Xylometazoline can interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.
  • Systemic antihypertensive agents: additive blood‑pressure‑lowering effect.

Moderate Interactions (Monitor Closely)

  • Other topical nasal decongestants: increased risk of rebound congestion.
  • Oral sympathomimetic decongestants (e.g., pseudoephedrine): potential for excessive vasoconstriction.
  • Certain ophthalmic decongestant drops: may enhance systemic adrenergic effects.

Frequently Asked Questions

Nasic Pur is an over‑the‑counter nasal spray that combines xylometazoline hydrochloride and dexpanthenol to relieve nasal congestion caused by the common cold, sinusitis and allergic rhinitis. It works by narrowing swollen blood vessels in the nasal lining, allowing easier breathing.

Xylometazoline is an α‑adrenergic agonist. When applied to the nasal mucosa it stimulates α1‑receptors on vascular smooth muscle, causing vasoconstriction. This reduces swelling and excess fluid in the nasal passages, quickly opening the airway. Dexpanthenol simultaneously supports mucosal healing.

The exact dosing regimen for Nasic Pur is determined by the prescribing healthcare professional. Typically, a few sprays per nostril are used, but the prescriber will set the frequency and duration based on the patient’s age, condition severity and response to therapy.

Safety data for xylometazoline and dexpanthenol in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using Nasic Pur.

To place an order, submit an enquiry on the Nasic Pur product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Nasic Pur combines xylometazoline with dexpanthenol, offering both rapid decongestion and mucosal moisturisation. Compared with oxymetazoline‑only products, it may cause slightly less dryness because dexpanthenol helps maintain epithelial health, though both agents share similar efficacy and risk of rebound congestion if used beyond recommended duration.

Store Nasic Pur at room temperature, below 25 °C, in its original packaging. Keep the bottle tightly closed, protect it from moisture, direct sunlight and extreme heat. Do not freeze the product, and keep it out of reach of children.

Nasic Pur is administered as a nasal spray. Gently blow the nose to clear excess mucus, tilt the head slightly forward, insert the nozzle into one nostril, and press the pump to deliver the recommended number of sprays. Repeat in the other nostril if instructed, and avoid blowing the nose immediately after use.

Serious risks include rebound nasal congestion (rhinitis medicamentosa) after prolonged use, significant elevation of blood pressure or heart rate, and rare severe allergic reactions such as anaphylaxis. Patients experiencing persistent nasal blockage, hypertension, chest pain, or signs of an allergic response should discontinue use and seek medical attention promptly.

Nasic Pur should be avoided in children younger than 6 years, individuals with severe hypertension, those taking monoamine oxidase inhibitors, or patients with known hypersensitivity to xylometazoline, dexpanthenol or any excipients. Persons with certain cardiovascular disorders should consult a physician before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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