Nasic (Xylometazoline Hydrochloride, Dexpanthenol)

• Nasic, containing xylometazoline, acts on nasal vascular tone to alleviate congestion in upper‑respiratory conditions.
• Common cold: reduces nasal blockage and improves airflow.
• Sinusitis: decreases mucosal edema, facilitating sinus drainage.
• Allergic rhinitis: lessens nasal swelling and congestion caused by allergens.

• Xylometazoline Hydrochloride binds to α‑adrenergic receptors on nasal mucosal blood vessels, producing vasoconstriction that limits plasma exudation and edema. Dexpanthenol, a provitamin B5 derivative, is converted to pantothenic acid in epithelial cells, supporting membrane repair and providing moisturisation of the nasal mucosa.

Nasic may cause local or systemic adverse reactions, most of which are mild and transient.

Common Side Effects

• Nasal irritation or burning sensation
• Dryness of the nasal mucosa
• Sneezing
• Taste disturbance or mild headache

Serious or Rare Side Effects

• Severe nosebleeds (epistaxis)
• Allergic reactions such as rash, swelling or anaphylaxis
• Nasal ulceration or perforation with prolonged misuse

• Before using Nasic, consider the following precautions to minimise risk.
• Pregnancy: consult a healthcare professional; safety data are limited.
• Children under six years: avoid unless specifically prescribed.
• Duration of use: limit to no more than five consecutive days to prevent rebound congestion.
• Existing nasal disease: use with caution in patients with severe nasal septum deviation or trauma.
• Concurrent sympathomimetic drugs: monitor for additive cardiovascular effects.
• Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Nasic can interact with other medicines; awareness of potential interactions helps ensure safe use.

Major Interactions (Avoid)

• Monoamine oxidase inhibitors: may increase risk of hypertensive response.
• Other nasal decongestants (e.g., phenylephrine): risk of excessive vasoconstriction.
• Systemic sympathomim