Product image of Nasic (Xylometazoline Hydrochloride, Dexpanthenol) supplied by GNH India

Nasic

Active Ingredient:
Xylometazoline Hydrochloride, Dexpanthenol
Origin:
EU

Nasic (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline Hydrochloride, the active ingredient in Nasic, is an alpha‑adrenergic agonist presented as a nasal spray for nasal use. It relieves nasal congestion associated with the common cold, sinusitis and allergic rhinitis in both adults and children, helping to restore normal breathing. It is intended for short‑term use to avoid rebound congestion.

GNH India supplies Nasic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality assurance and regulatory standards across all markets.

Manufacturer / TM Owner

Cassella-Med Gmbh & Co. Kg

1
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Indications & Clinical Uses

Nasic, containing Xylometazoline Hydrochloride, acts on nasal blood vessels to reduce swelling and improve airflow.

  • Common cold nasal congestion: reduces swelling of nasal mucosa, improving breathing during viral upper respiratory infection.
  • Sinusitis-related nasal blockage: alleviates congestion and facilitates sinus drainage.
  • Allergic rhinitis: decreases nasal obstruction and improves airflow in allergic reactions.

How It Works

  • Xylometazoline Hydrochloride selectively stimulates α‑adrenergic receptors on the smooth muscle of nasal blood vessels, causing vasoconstriction that decreases mucosal edema and limits secretions. Dexpanthenol, a vitamin B5 derivative, supports epithelial cell proliferation and moisturises the nasal lining, aiding tissue repair while the decongestant effect restores patency of the airway. The combined action provides rapid relief of obstruction and promotes mucosal healing during short‑term therapy.

Side Effects

Nasic may cause local and systemic adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Dryness of the nasal passages.
  • Sneezing or mild nosebleeds.
  • Headache.
  • Altered taste or bitter taste.
  • Mild dizziness.

Serious or Rare Side Effects

  • Severe hypertension or rapid increase in blood pressure.
  • Cardiac arrhythmias.
  • Rebound nasal congestion after prolonged use.
  • Allergic reaction such as rash, itching or swelling.
  • Anaphylaxis (rare but life‑threatening).
  • Nasal septum perforation with misuse.

Precautions & Warnings

Before using Nasic, consider the following precautions to ensure safe and effective treatment.

  • Limit duration of use: restrict to 3‑5 days to prevent rebound congestion.
  • Avoid in uncontrolled hypertension: may raise blood pressure.
  • Contraindicated in children under 2 years: safety not established.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Concurrent use with MAO inhibitors: may increase cardiovascular effects.
  • Store at room temperature: keep in original container, protect from moisture and heat.

Avoid Interactions

Nasic can interact with other medicines; be aware of the following potential interactions.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.
  • Other nasal decongestants (e.g., oxymetazoline): additive vasoconstriction.
  • Systemic sympathomimetics (e.g., pseudoephedrine): increased cardiovascular stimulation.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents (e.g., beta‑blockers): possible reduction in blood pressure control.
  • Corticosteroid nasal sprays: monitor for local irritation.
  • Alcohol: may enhance dizziness or headache.

Frequently Asked Questions

Nasic is an over‑the‑counter nasal spray that relieves nasal congestion caused by the common cold, sinusitis and allergic rhinitis. It works by shrinking swollen blood vessels in the nasal lining, helping the airway stay open for easier breathing.

Xylometazoline Hydrochloride is a selective alpha‑adrenergic agonist. By binding to α‑receptors on nasal blood‑vessel smooth muscle, it triggers vasoconstriction, which reduces mucosal swelling and limits excess secretions, thereby clearing the nasal passages.

The exact dose and frequency are determined by the prescribing healthcare professional. Typically, a few sprays per nostril are used for short‑term relief, but the prescriber will provide specific instructions based on the patient’s age and condition.

Safety in pregnancy and lactation has not been definitively established. Women who are pregnant, planning a pregnancy, or breastfeeding should discuss use with their physician to weigh potential benefits against any unknown risks.

To place an order, submit an enquiry on the Nasic product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nasic combines Xylometazoline with Dexpanthenol, offering both rapid decongestion and moisturising/repair benefits. Compared with single‑agent sprays, the added Dexpanthenol may help maintain nasal mucosal health, while the decongestant potency is similar to other α‑adrenergic nasal sprays.

Store Nasic at room temperature, away from direct sunlight and excessive heat. Keep the bottle tightly closed in its original packaging to protect it from moisture. Do not freeze the product, and discard it after the expiration date printed on the label.

Nasic is applied directly into each nostril using the spray nozzle. The user should tilt the head slightly forward, insert the tip into the nostril, and press the pump to deliver the recommended number of sprays. Avoid blowing the nose immediately after application.

Serious adverse events, although rare, include a sudden rise in blood pressure, cardiac arrhythmias, severe allergic reactions such as anaphylaxis, and rebound congestion if used longer than recommended. Any signs of these conditions require immediate medical attention.

Nasic should be avoided by individuals with uncontrolled hypertension, known hypersensitivity to Xylometazoline or Dexpanthenol, children under two years of age, and patients taking monoamine oxidase inhibitors. Consultation with a healthcare professional is essential for anyone with significant cardiovascular disease.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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