Product image of Nasic (Xylometazoline Hydrochloride, Dexpanthenol) supplied by GNH India

Nasic

Active Ingredient:
Xylometazoline Hydrochloride, Dexpanthenol
Origin:
EU

Nasic (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline Hydrochloride, the active ingredient in Nasic, is an alpha‑adrenergic agonist presented as a nasal spray for nasal use. It relieves nasal congestion associated with the common cold, acute rhinitis and sinusitis in adults and children.

GNH India supplies Nasic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cassella-Med Gmbh & Co. Kg

1
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Indications & Clinical Uses

  • Nasic acts on the nasal mucosa to reduce swelling and improve airflow in common upper‑respiratory conditions.
  • Nasal congestion due to common cold: provides rapid decongestion and easier breathing.
  • Acute rhinitis: reduces mucosal swelling and nasal blockage.
  • Sinusitis‑associated nasal blockage: eases obstruction and supports sinus drainage.

How It Works

  • Xylometazoline Hydrochloride selectively stimulates alpha‑2 adrenergic receptors on the nasal vasculature, causing vasoconstriction and reduced mucosal edema. Dexpanthenol, a provitamin B5 derivative, enhances epithelial cell proliferation and restores the mucosal barrier, supporting healing of the nasal lining while the decongestant effect persists.

Side Effects

Nasic may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nasal irritation or burning sensation
  • Dryness of the nasal mucosa
  • Sneezing or mild nosebleeds
  • Headache
  • Altered taste or bitter after‑taste
  • Mild dizziness

Serious or Rare Side Effects

  • Severe epistaxis (heavy nosebleed)
  • Allergic reactions such as rash, itching, or angioedema
  • Paradoxical worsening of congestion (rebound congestion)
  • Nasal ulceration or perforation with prolonged use
  • Anaphylaxis (rare but life‑threatening)
  • Vision changes if spray contacts the eyes

Precautions & Warnings

  • Before using Nasic, consider the following safety measures.
  • Pregnancy: consult a healthcare professional as safety data are limited.
  • Breastfeeding: discuss potential risks with a physician.
  • Age restrictions: not recommended for children under 2 years of age.
  • Pre‑existing nasal conditions: avoid if severe septal deviation, recent nasal surgery, or chronic rhinitis.
  • Concurrent nasal medications: limit use with other decongestants to prevent excessive vasoconstriction.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Nasic can interact with other agents that affect vascular tone or blood pressure.

Major Interactions (Avoid)

  • Other nasal decongestants: risk of excessive vasoconstriction and rebound congestion.
  • Monoamine oxidase inhibitors (MAOIs): theoretical risk of hypertensive episodes.
  • Systemic sympathomimetics: additive cardiovascular stimulation.

Moderate Interactions (Monitor Closely)

  • Antihypertensive drugs: possible reduction in blood‑pressure‑lowering effect.
  • Topical nasal steroids: monitor for increased local irritation.
  • Alcohol or sedatives: may enhance dizziness or drowsiness.

Frequently Asked Questions

Nasic is an over‑the‑counter nasal spray that combines Xylometazoline Hydrochloride and Dexpanthenol to relieve nasal congestion caused by the common cold, acute rhinitis, and sinusitis‑related blockage. It works by shrinking swollen blood vessels in the nasal passages and supporting mucosal healing, helping patients breathe more easily.

Xylometazoline Hydrochloride is a selective alpha‑2 adrenergic receptor agonist. By binding to these receptors on the nasal blood vessels, it triggers vasoconstriction, which reduces swelling of the nasal mucosa and opens the airway. This rapid decongestant effect eases breathing during upper‑respiratory infections.

The exact dosing regimen for Nasic is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms, and clinical judgment. Typically, the label advises a limited number of sprays per nostril, but the prescriber sets the final instructions.

Safety data for Nasic in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Nasic combines a potent alpha‑adrenergic agonist (Xylometazoline) with Dexpanthenol, which promotes mucosal repair. Compared with single‑ingredient decongestants, Nasic may offer added soothing and healing benefits, while still providing rapid relief. However, clinical choice depends on individual patient needs and physician preference.

Nasic should be stored at room temperature, ideally below 25 °C. Keep the spray bottle in its original packaging, protect it from moisture and direct sunlight, and ensure the cap is tightly closed to maintain product stability.

Nasic is administered as a nasal spray. The user gently inserts the nozzle into one nostril, inhales gently, and actuates the pump to deliver the recommended number of sprays. The process is repeated in the other nostril if directed by the prescriber.

Serious risks, though rare, include heavy nosebleeds, severe allergic reactions such as rash or angioedema, paradoxical worsening of congestion (rebound effect) with prolonged use, and nasal ulceration or perforation. Any signs of these reactions require immediate medical attention.

Nasic should be avoided in children younger than 2 years, individuals with known hypersensitivity to Xylometazoline, Dexpanthenol, or any excipients, and patients with severe nasal septum deviation, recent nasal surgery, or chronic nasal conditions unless advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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