Product image of Nasic (Xylometazoline Hydrochloride, Dexpanthenol) supplied by GNH India

Nasic

Active Ingredient:
Xylometazoline Hydrochloride, Dexpanthenol
Origin:
EU

Nasic (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline Hydrochloride, the active ingredient in Nasic, is a alpha‑adrenergic agonist presented as a nasal spray for nasal use. It treats nasal congestion associated with the common cold, sinusitis and allergic rhinitis. Dexpanthenol, a mucosal protectant, supports epithelial repair and moisturisation.

GNH India supplies Nasic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cassella-Med Gmbh & Co. Kg

1
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Indications & Clinical Uses

Nasic, containing an alpha‑adrenergic nasal decongestant and a mucosal protectant, relieves nasal obstruction in several upper‑respiratory conditions.

  • Common cold: reduces nasal congestion and improves airflow.
  • Sinusitis: alleviates blockage of the nasal passages associated with sinus inflammation.
  • Allergic rhinitis: decreases swelling of nasal mucosa caused by allergen exposure.

How It Works

  • Xylometazoline Hydrochloride acts as a selective alpha‑adrenergic receptor agonist on the vascular smooth muscle of the nasal mucosa, producing vasoconstriction that reduces edema and opens the airway. Dexpanthenol, a derivative of vitamin B5, enhances epithelial cell proliferation and moisturises the mucosal surface, supporting repair of the nasal lining.

Side Effects

Nasic may cause local or systemic adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nasal burning or stinging.
  • Mild dryness of the nasal mucosa.
  • Sneezing.
  • Transient taste disturbance.

Serious or Rare Side Effects

  • Persistent nasal irritation or ulceration.
  • Severe hypertension.
  • Allergic reaction with rash or swelling.
  • Nasal septum perforation (very rare).

Precautions & Warnings

Before using Nasic, consider the following precautions to ensure safe and effective treatment.

  • Age restriction: not recommended for children under 2 years without medical advice.
  • Cardiovascular disease: use cautiously in patients with hypertension or heart disease.
  • Recent nasal surgery: avoid immediate use after nasal procedures.
  • Concomitant monoamine oxidase inhibitors: consult a physician before combining.
  • Prolonged use: limit to three consecutive days to prevent rebound congestion.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Nasic can interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may increase risk of hypertensive episodes.
  • Systemic decongestants (e.g., pseudoephedrine): additive vasoconstrictive effect can raise blood pressure.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: nasal vasoconstriction may reduce efficacy of blood pressure medications.
  • Beta‑blockers: possible enhancement of vasoconstrictive response.
  • Nasal corticosteroids: monitor for increased local irritation.

Frequently Asked Questions

Nasic is an over‑the‑counter nasal spray that combines Xylometazoline Hydrochloride, a rapid‑acting decongestant, with Dexpanthenol, a mucosal protectant. It is used to relieve nasal blockage caused by the common cold, sinusitis and allergic rhinitis, helping patients breathe more easily through the nose.

Xylometazoline Hydrochloride selectively stimulates alpha‑adrenergic receptors on the blood vessels of the nasal mucosa. This causes vasoconstriction, which reduces swelling and excess fluid, opening the nasal passages and decreasing the sensation of congestion.

The exact dose of Nasic is determined by the prescribing healthcare professional. Typically, a few sprays into each nostril are administered, but the prescriber will specify the number of sprays, frequency and duration based on the individual’s condition.

Safety data for Xylometazoline Hydrochloride and Dexpanthenol in pregnancy or lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using Nasic to weigh potential benefits against risks.

To order Nasic, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nasic combines a fast‑acting alpha‑adrenergic decongestant (Xylometazoline) with Dexpanthenol, which promotes mucosal healing. Compared with single‑ingredient sprays such as oxymetazoline, Nasic may offer added moisturising benefits, though the core decongestant effect is similar.

Store Nasic at room temperature, preferably below 25 °C, in its original packaging. Keep the bottle tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

Nasic is administered as a nasal spray. The user should gently blow the nose, tilt the head slightly forward, insert the nozzle into one nostril, and press the pump to deliver the recommended number of sprays. The process is repeated in the other nostril if advised.

Serious but rare risks include persistent nasal irritation or ulceration, severe hypertension, allergic reactions such as rash or swelling, and, in extremely uncommon cases, perforation of the nasal septum. Any of these symptoms should prompt immediate medical attention.

Nasic should be avoided in individuals with known hypersensitivity to Xylometazoline, Dexpanthenol or any excipients, in children under two years of age unless directed by a physician, and in patients with severe hypertension or recent nasal surgery without professional guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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