Product image of Nasic (Xylometazoline Hydrochloride, Dexpanthenol) supplied by GNH India

Nasic

Active Ingredient:
Xylometazoline Hydrochloride, Dexpanthenol
Origin:
EU

Nasic (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline Hydrochloride, the active ingredient in Nasic, is an alpha‑adrenergic agonist presented as a nasal spray for intranasal use. It works together with Dexpanthenol, a provitamin B5 derivative, to relieve nasal congestion and support mucosal healing in patients with upper‑respiratory conditions.

GNH India supplies Nasic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cassella-Med Gmbh & Co. Kg

1
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Indications & Clinical Uses

Nasic combines an alpha‑adrenergic nasal decongestant with a mucosal protectant to address common upper‑respiratory complaints.

  • Common cold (nasal congestion): reduces swelling of the nasal mucosa to improve airflow.
  • Acute sinusitis: alleviates blockage and facilitates sinus drainage.
  • Allergic rhinitis: diminishes congestion caused by allergic inflammation.

How It Works

  • Xylometazoline Hydrochloride selectively stimulates alpha‑adrenergic receptors on the vascular smooth muscle of the nasal mucosa, causing vasoconstriction and decreasing edema. Dexpanthenol is enzymatically converted to pantothenic acid, which participates in cellular metabolism and promotes regeneration of the nasal epithelium, enhancing mucosal integrity.

Side Effects

Adverse reactions may occur with intranasal use of Nasic. Most are mild and reversible.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Sneezing.
  • Dryness of the nasal passages.
  • Mild headache.
  • Transient taste disturbance.

Serious or Rare Side Effects

  • Persistent nasal bleeding.
  • Severe hypertension.
  • Allergic rash or angioedema.
  • Vision changes.
  • Nasal septum perforation (with prolonged misuse).

Precautions & Warnings

Before using Nasic, consider the following safety measures.

  • Duration of use: limit to no more than 3‑5 consecutive days to avoid rebound congestion.
  • Cardiovascular disease: use with caution in patients with hypertension or heart disease.
  • Pregnancy: consult a healthcare professional before use, as safety data are limited.
  • Children: follow pediatric guidance; product may not be suitable for very young ages.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Nasic may interact with other medications that affect vascular tone or blood pressure.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of excessive vasoconstriction.
  • Systemic decongestants (e.g., pseudoephedrine): additive hypertensive effect.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: may reduce their efficacy.
  • Nasal corticosteroids: monitor for increased local irritation.
  • Anticholinergic drugs: watch for heightened dryness of mucous membranes.

Frequently Asked Questions

Nasic is indicated for relief of nasal congestion associated with the common cold, acute sinusitis, and allergic rhinitis. By narrowing swollen blood vessels in the nasal lining and supporting mucosal health, it helps restore normal breathing in these upper‑respiratory conditions.

Xylometazoline Hydrochloride acts as a selective alpha‑adrenergic receptor agonist. When applied to the nasal mucosa, it triggers vasoconstriction of the small blood vessels, which reduces swelling and opens the nasal passages, providing rapid decongestion.

The appropriate dose of Nasic is determined by a qualified healthcare professional based on the patient’s age, condition severity, and response to therapy. Users should follow the prescriber’s instructions and the product label for the number of sprays per nostril and treatment duration.

Safety data for Nasic in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using the product to weigh potential benefits against any unknown risks.

To place an order, submit an enquiry on the Nasic product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Nasic combines an alpha‑adrenergic decongestant (xylometazoline) with a mucosal protectant (dexpanthenol), offering both rapid relief and support for nasal tissue healing. Compared with single‑agent decongestants, it may reduce irritation and promote faster mucosal recovery, though clinical choice depends on individual patient needs.

Store Nasic at room temperature, preferably below 25 °C. Keep the bottle tightly closed, protect it from moisture and direct sunlight, and retain it in the original packaging until use to maintain product stability.

Nasic is administered intranasally as a spray. The usual instruction is to tilt the head slightly forward, insert the nozzle into one nostril, and spray the prescribed number of sprays while breathing in gently. Repeat in the other nostril if directed by the prescriber.

Serious adverse events, though rare, can include persistent nasal bleeding, severe hypertension, allergic reactions such as rash or angioedema, and, with prolonged misuse, nasal septum perforation. Users should discontinue the product and seek medical attention if any of these occur.

Nasic should be avoided in individuals with known hypersensitivity to xylometazoline, dexpanthenol, or any excipients in the formulation. It is also contraindicated in patients with severe hypertension, certain cardiovascular disorders, or those who have experienced rebound congestion from overuse of topical decongestants.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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