Product image of Nasic (Xylometazoline Hydrochloride, Dexpanthenol) supplied by GNH India

Nasic

Active Ingredient:
Xylometazoline Hydrochloride, Dexpanthenol
Origin:
EU

Nasic (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline Hydrochloride and Dexpanthenol, the active ingredients in Nasic, are an alpha‑adrenergic agonist nasal decongestant and a provitamin B5, presented as a nasal spray for nasal use. It relieves nasal congestion associated with the common cold, sinusitis and allergic rhinitis in adults and children.

GNH India supplies Nasic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cassella-Med Gmbh & Co. Kg

1
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Indications & Clinical Uses

Nasic, containing xylometazoline hydrochloride and dexpanthenol, is used to alleviate nasal congestion in upper‑respiratory conditions.

  • Common cold: reduces nasal blockage and improves breathing.
  • Sinusitis: alleviates congestion and facilitates sinus drainage.
  • Allergic rhinitis: decreases nasal swelling and congestion caused by allergens.

How It Works

  • Xylometazoline hydrochloride selectively stimulates alpha‑adrenergic receptors on the vascular smooth muscle of the nasal mucosa, causing vasoconstriction and reduced edema. Dexpanthenol, a provitamin B5 derivative, is converted to pantothenic acid in the mucosa, supporting cellular repair and providing moisturisation, which together improve nasal airway patency.

Side Effects

Nasic may cause local or systemic adverse reactions, most of which are mild and transient.

Common Side Effects

  • Nasal irritation: mild burning or stinging sensation.
  • Sneezing: transient increase in sneezing episodes.
  • Dryness of nasal mucosa: mild dryness or crusting.
  • Headache: occasional mild headache.

Serious or Rare Side Effects

  • Severe nasal bleeding: epistaxis requiring medical attention.
  • Allergic reaction: rash, itching, swelling, or anaphylaxis.
  • Elevated blood pressure: rare systemic vasoconstrictive effect.

Precautions & Warnings

Before using Nasic, consider the following safety measures.

  • Use in children: limit use in children under 6 years unless directed by a physician.
  • Duration of use: do not exceed 3‑5 days to avoid rebound congestion.
  • Cardiovascular conditions: caution in patients with hypertension or heart disease.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Concomitant nasal sprays: avoid using other decongestant sprays simultaneously.
  • Store at room temperature: keep below 25 °C, protect from moisture and direct sunlight.

Avoid Interactions

Nasic can interact with other medicines; some combinations require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis due to additive vasoconstriction.
  • Other nasal decongestants: combined use may increase rebound congestion and systemic vasoconstriction.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: nasal vasoconstriction may reduce blood‑pressure‑lowering effect.
  • Beta‑blockers: may mask tachycardia caused by systemic absorption.
  • Corticosteroid nasal sprays: generally safe but monitor for increased local irritation.

Frequently Asked Questions

Nasic is an over‑the‑counter nasal spray that combines xylometazoline hydrochloride and dexpanthenol to relieve nasal congestion caused by the common cold, sinusitis and allergic rhinitis. It works by narrowing swollen blood vessels in the nasal lining and supporting mucosal repair, helping patients breathe more easily.

Xylometazoline is a selective alpha‑adrenergic agonist. When applied to the nasal mucosa it binds to alpha‑1 receptors on the smooth muscle of nasal blood vessels, causing vasoconstriction. This reduces swelling and excess mucus, opening the airway. Dexpanthenol simultaneously promotes mucosal healing and moisturisation.

The exact dosing regimen for Nasic is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms and clinical judgment. The product label provides standard instructions, but patients should follow the dose prescribed by their doctor or pharmacist.

Safety data for Nasic in pregnancy and lactation are limited. Women who are pregnant, planning a pregnancy, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using the spray.

To order Nasic, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Nasic combines a fast‑acting decongestant (xylometazoline) with a mucosal‑protective agent (dexpanthenol), whereas many alternatives such as oxymetazoline contain only the vasoconstrictor. The added dexpanthenol may reduce dryness and support healing, potentially offering better tolerability for short‑term use.

Store Nasic at room temperature, preferably below 25 °C, in its original container. Keep the bottle tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

Nasic is sprayed into each nostril while the head is upright. Typically, one or two sprays per nostril are used, but the exact number should follow the prescribing clinician’s instructions. The spray should be directed away from the nasal septum to minimise irritation.

Serious adverse events are rare but may include severe nosebleeds (epistaxis), allergic reactions such as rash, swelling, or anaphylaxis, and a sudden increase in blood pressure. If any of these occur, discontinue use immediately and seek medical attention.

Nasic should be avoided in individuals with known hypersensitivity to xylometazoline, dexpanthenol or any excipients, in patients with severe hypertension or uncontrolled cardiovascular disease, and in children younger than the age specified on the label unless a physician advises otherwise.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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