Product image of Nasic (Xylometazoline Hydrochloride, Dexpanthenol) supplied by GNH India

Nasic

Active Ingredient:
Xylometazoline Hydrochloride, Dexpanthenol
Origin:
EU

Nasic (Xylometazoline Hydrochloride, Dexpanthenol)

Xylometazoline Hydrochloride, the active ingredient in Nasic, is an alpha‑adrenergic agonist presented as a nasal spray for intranasal use. It reduces swelling of the nasal mucosa, providing rapid relief of nasal congestion in adults and children suffering from the common cold, allergic rhinitis, or sinus irritation.

GNH India supplies Nasic as a licensed, GDP‑compliant international pharmaceutical supplier, providing reliable sourcing and regulatory support to hospitals, pharmacies, and clinics worldwide, with efficient logistics for timely delivery across multiple global markets.

Manufacturer / TM Owner

Cassella-Med Gmbh & Co. Kg

1
Pack/s
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Indications & Clinical Uses

Nasic, containing xylometazoline hydrochloride and dexpanthenol, works on nasal vascular tone and mucosal healing to relieve congestion.

  • Nasal congestion: rapid decongestion of swollen nasal passages.
  • Common cold: alleviates blockage and improves breathing during viral upper respiratory infection.
  • Allergic rhinitis: reduces nasal swelling caused by allergen exposure.

How It Works

  • Xylometazoline hydrochloride selectively stimulates α‑adrenergic receptors on nasal blood vessels, causing vasoconstriction and reduced mucosal edema. Dexpanthenol, a provitamin B5, is converted to pantothenic acid in epithelial cells, promoting cell proliferation, repair and moisturisation of the nasal mucosa, supporting faster recovery.

Side Effects

Nasic may cause local and systemic reactions, most of which are mild and transient.

Common Side Effects

  • Nasal irritation: mild burning or stinging sensation.
  • Dryness of nasal mucosa.
  • Sneezing.
  • Headache.
  • Altered taste perception.
  • Mild epistaxis.

Serious or Rare Side Effects

  • Severe hypertension or hypertensive crisis.
  • Cardiac arrhythmia.
  • Nasal ulceration or perforation with prolonged use.
  • Anaphylactic reaction.
  • Vision disturbances.
  • Persistent nasal bleeding.

Precautions & Warnings

Use Nasic according to label instructions and medical advice.

  • Limit duration of use: avoid continuous use longer than 7 days to prevent rebound congestion.
  • Hypertension caution: monitor blood pressure if patient has high blood pressure.
  • Pediatric restriction: not recommended for children under 2 years of age.
  • Pregnancy and lactation: consult a healthcare professional as safety has not been established.
  • Concomitant nasal decongestants: avoid using other topical decongestants simultaneously.
  • Store at room temperature: keep in original container, protect from moisture and heat.

Avoid Interactions

Nasic can interact with other sympathomimetic agents and systemic medications.

Major Interactions (Avoid)

  • Other nasal or oral decongestants (e.g., phenylephrine, pseudoephedrine): additive vasoconstriction may increase cardiovascular risk.
  • Monoamine oxidase inhibitors (MAOIs): combined use may precipitate hypertensive crisis.
  • β‑blockers: may diminish decongestant effect and alter cardiovascular response.

Moderate Interactions (Monitor Closely)

  • Antihypertensive drugs: possible reduction in blood‑pressure‑lowering effect.
  • Antidepressants (SSRIs, SNRIs): monitor for increased blood pressure.
  • Alcohol: may enhance dizziness or headache.

Frequently Asked Questions

Nasic is an over‑the‑counter nasal spray that combines xylometazoline hydrochloride, a rapid‑acting decongestant, with dexpanthenol, a skin‑protective agent. It is intended to relieve nasal blockage caused by the common cold, sinusitis, or allergic rhinitis by shrinking swollen blood vessels and supporting mucosal healing.

Xylometazoline Hydrochloride acts as a selective α‑adrenergic agonist. By binding to α‑receptors on the blood vessels of the nasal lining, it triggers vasoconstriction, which reduces swelling and opens the airway, allowing easier breathing during episodes of congestion.

The exact dosing regimen for Nasic is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms, and clinical judgment. Users should follow the label instructions and the prescriber’s guidance without exceeding the recommended number of sprays per day.

Safety data for Nasic in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their physician before using the product to weigh potential benefits against any uncertain risks.

To request Nasic, visit the product page on gnhindia.com, enter the required quantity, and submit the enquiry form. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with single‑ingredient decongestants such as oxymetazoline, Nasic adds dexpanthenol, which helps moisturise and repair the nasal mucosa. This combination may reduce the feeling of dryness that some users experience with plain vasoconstrictors, while providing comparable rapid relief of congestion.

Nasic should be stored at room temperature, ideally below 25 °C. Keep the bottle tightly closed in its original packaging, protect it from direct sunlight, moisture and extreme heat to maintain product stability and effectiveness.

Nasic is applied as a nasal spray. The user gently inserts the tip into one nostril, tilts the head slightly forward, and presses the pump to deliver the recommended number of sprays. The same procedure is repeated in the other nostril if instructed by the prescriber.

Serious adverse events, although rare, can include severe hypertension, cardiac arrhythmias, nasal ulceration or perforation with prolonged use, and anaphylactic reactions. Any sudden increase in blood pressure, chest pain, severe nosebleeds, or signs of an allergic reaction should prompt immediate medical attention.

Nasic should be avoided in children younger than 2 years, in individuals with known hypersensitivity to xylometazoline, dexpanthenol, or any excipients, and in patients taking monoamine oxidase inhibitors or other potent sympathomimetics without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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