Product image of Nasiflair (Chlorphenamine Maleate, Sodium Cromoglicate) supplied by GNH India

Nasiflair

Active Ingredient:
Chlorphenamine Maleate, Sodium Cromoglicate
Origin:
EU

Nasiflair (Chlorphenamine Maleate, Sodium Cromoglicate)

Chlorphenamine maleate and sodium cromoglicate, the active ingredients in Nasiflair, are an antihistamine and mast cell stabilizer presented as a nasal spray for intranasal use. It treats allergic rhinitis and related nasal allergy symptoms in adults and children.

GNH India supplies Nasiflair as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Verisfield S.M.S.A

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Indications & Clinical Uses

  • Nasiflair is indicated for conditions affecting the nasal passages that involve histamine‑mediated inflammation.
  • Allergic rhinitis: reduces nasal congestion, sneezing, itching and watery discharge.
  • Seasonal allergic rhinitis: alleviates symptoms triggered by pollen or outdoor allergens.
  • Nasal allergy: provides relief from chronic nasal irritation and obstruction caused by allergen exposure.

How It Works

  • Chlorphenamine maleate blocks H1 histamine receptors, preventing the typical allergic response such as vasodilation and increased vascular permeability. Sodium cromoglicate stabilises mast cells, inhibiting degranulation and the subsequent release of inflammatory mediators like histamine, leukotrienes and prostaglandins, thereby reducing nasal inflammation and symptom severity.

Side Effects

Common Side Effects

  • Nasal irritation or burning sensation.
  • Bitter taste after administration.
  • Drowsiness or mild sedation.
  • Headache.

Serious or Rare Side Effects

  • Anaphylactic or severe allergic reaction.
  • Significant nasal bleeding.
  • Swelling of the face, lips, tongue or throat.

Precautions & Warnings

Before using Nasiflair, consider the following precautions:

  • Allergy history: verify no known hypersensitivity to chlorphenamine, sodium cromoglicate or excipients.
  • Asthma or reactive airway disease: use with caution and monitor for bronchospasm.
  • Sedation: avoid operating machinery or driving if drowsiness occurs.
  • Frequency: do not exceed the prescribed number of sprays per day.
  • Store at room temperature: keep in the original container, protect from moisture and direct heat.

Avoid Interactions

Nasiflair may interact with other medicines as follows:

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.
  • Other antihistamines: additive sedation and anticholinergic effects.
  • Central nervous system depressants (e.g., benzodiazepines, opioids): enhanced drowsiness.
  • Alcohol: increased sedation and impaired coordination.

Moderate Interactions (Monitor Closely):\n- Beta‑blockers: may reduce effectiveness of rescue epinephrine in severe allergic reactions.

  • Tricyclic antidepressants: possible increase in anticholinergic side effects.
  • CYP450 enzyme inhibitors: may alter plasma levels of chlorphenamine.

Frequently Asked Questions

Nasiflair is a nasal spray that combines chlorphenamine maleate and sodium cromoglicate to relieve symptoms of allergic rhinitis, seasonal allergic rhinitis and other nasal allergies. It helps reduce sneezing, itching, nasal congestion and watery discharge caused by histamine release in the nasal passages.

Chlorphenamine maleate is an H1‑receptor antagonist. By blocking H1 histamine receptors on nasal mucosal cells, it prevents histamine‑induced vasodilation, increased permeability and nerve stimulation, which are responsible for itching, sneezing and nasal congestion during an allergic response.

The exact dosing regimen for Nasiflair is determined by the prescribing healthcare professional based on the patient’s age, severity of symptoms and clinical response. Patients should follow the prescriber’s instructions and not exceed the recommended number of sprays per day.

Safety data for chlorphenamine maleate and sodium cromoglicate in pregnancy and lactation are limited. The prescriber should weigh the potential benefits against any possible risks before recommending Nasiflair to pregnant or nursing women. Consultation with a healthcare provider is essential.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Nasiflair combines an H1‑antihistamine (chlorphenamine) with a mast‑cell stabiliser (sodium cromoglicate), offering both immediate symptom relief and longer‑term reduction of mediator release. Some alternatives contain only an antihistamine, which may provide rapid relief but lack the additional mast‑cell stabilising effect that can help prevent symptom recurrence.

Store Nasiflair at room temperature, below 25 °C. Keep the bottle in its original packaging, protect it from moisture and direct sunlight, and ensure the cap is tightly closed to maintain spray integrity.

Nasiflair is administered as a nasal spray. The patient should gently blow the nose, tilt the head slightly forward, insert the nozzle into one nostril, and spray the prescribed number of actuations while breathing in gently. The process is repeated in the other nostril if directed by the prescriber.

The most serious risks include severe allergic reactions such as anaphylaxis, significant nasal bleeding, and swelling of the face, lips, tongue or throat that could compromise breathing. Immediate medical attention is required if any of these symptoms occur.

Nasiflair should be avoided in individuals with known hypersensitivity to chlorphenamine, sodium cromoglicate or any formulation excipients. It is also contraindicated in patients who have experienced severe reactions to other antihistamines or mast‑cell stabilisers, and in those for whom the prescriber determines the risks outweigh the benefits.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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