Product image of Nasin (Oxymetazoline Hydrochloride) supplied by GNH India

Nasin

Active Ingredient:
Oxymetazoline Hydrochloride
Origin:
EU

Nasin (Oxymetazoline Hydrochloride)

Oxymetazoline Hydrochloride, the active ingredient in Nasin, is a alpha‑adrenergic agonist presented as a nasal spray for topical nasal use. It provides temporary relief of nasal congestion associated with the common cold, sinusitis and allergic rhinitis.\n\nGNH India supplies Nasin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Perrigo Sverige Ab

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Indications & Clinical Uses

  • Oxymetazoline Hydrochloride is an alpha‑adrenergic agonist used to relieve nasal congestion in several common upper‑respiratory conditions.\n\n- Common cold: temporary relief of nasal congestion associated with viral upper‑respiratory infection.\n- Sinusitis: reduction of mucosal swelling to improve sinus drainage and breathing.\n- Allergic rhinitis: alleviation of nasal blockage caused by allergen‑induced inflammation.

How It Works

  • Oxymetazoline Hydrochloride acts as a selective alpha‑1 adrenergic receptor agonist. Stimulation of these receptors on the nasal mucosal blood vessels induces vasoconstriction, which reduces blood flow, edema, and secretions, thereby opening the nasal airway and easing congestion.

Side Effects

  • Nasin may cause a range of adverse reactions, most of which are mild and transient.\n\nCommon Side Effects:\n- Nasal irritation or burning sensation\n- Dryness of the nasal mucosa\n- Sneezing\n- Mild headache\n- Altered taste sensation\n- Transient epistaxis\n\nSerious or Rare Side Effects:\n- Rebound nasal congestion (rhinitis medicamentosa)\n- Significant elevation of blood pressure\n- Tachycardia or arrhythmia\n- Severe allergic reaction (anaphylaxis)\n- Ocular effects such as blurred vision\n- Nasal ulceration

Precautions & Warnings

  • Before using Nasin, consider the following safety measures.\n\n- Duration of use: limit to no more than three consecutive days to avoid rebound congestion.\n- Cardiovascular conditions: avoid if you have uncontrolled hypertension or severe coronary artery disease.\n- Children: not recommended for children under the age specified on the label unless directed by a healthcare professional.\n- Pregnancy and breastfeeding: consult a healthcare provider before use.\n- Drug interactions: review potential interactions with other medications (see Interactions section).\n- Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

  • Oxymetazoline may interact with other agents that affect the cardiovascular system or nasal vasculature.\n\nMajor Interactions (Avoid):\n- Other topical nasal decongestants: risk of excessive vasoconstriction and tissue damage.\n- Systemic sympathomimetics (e.g., pseudoephedrine): additive cardiovascular stimulation.\n- Monoamine oxidase inhibitors (MAOIs): potential for hypertensive crisis.\n\nModerate Interactions (Monitor Closely):\n- Beta‑blockers: may blunt compensatory tachycardia.\n- Tricyclic antidepressants: possible increase in blood pressure.\n- Clonidine: may reduce antihypertensive effect of clonidine.

Frequently Asked Questions

Nasin contains oxymetazoline hydrochloride, an over‑the‑counter nasal decongestant indicated for temporary relief of nasal congestion associated with the common cold, sinusitis and allergic rhinitis. It works locally in the nasal passages to reduce swelling and improve airflow.

Oxymetazoline is a selective alpha‑1 adrenergic receptor agonist. Activation of these receptors on nasal mucosal vessels causes vasoconstriction, decreasing blood flow and edema, which opens the nasal airway and eases congestion.

The appropriate dose is set by the prescribing healthcare professional or according to the product labeling. Typically, one or two sprays per nostril are administered every 10–12 hours, not exceeding the maximum daily frequency. Do not exceed the recommended duration of use.

Safety in pregnancy and lactation has not been fully established. Nasin should be used only if the potential benefit outweighs any risk. Pregnant or nursing women should discuss use with their healthcare provider before starting treatment.

Submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Oxymetazoline provides rapid, localized vasoconstriction and is available OTC, whereas systemic decongestants such as pseudoephedrine act throughout the body and may have broader cardiovascular effects. Oxymetazoline generally has fewer systemic side effects but shares the risk of rebound congestion with other topical agents.

Store below 25 °C in the original packaging, protected from moisture and direct sunlight. Keep the cap tightly closed when not in use and store out of reach of children.

Nasin is applied as a nasal spray. Gently blow the nose, insert the nozzle into each nostril, and press the pump to deliver the recommended number of sprays. Do not share the device and do not exceed the advised frequency.

Serious, though rare, adverse events include rebound nasal congestion (rhinitis medicamentosa), significant elevation of blood pressure, tachyarrhythmias, and severe allergic reactions such as anaphylaxis. Discontinue use and seek medical attention if any of these occur.

Individuals with known hypersensitivity to oxymetazoline or any formulation component, patients with severe hypertension, coronary artery disease, or those taking mono‑amine oxidase inhibitors should avoid Nasin unless directed by a physician. Children below the age specified on the label should also not use it.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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