Product image of Nasivin Classic (Oxymetazoline Hydrochloride) supplied by GNH India

Nasivin Classic

Active Ingredient:
Oxymetazoline Hydrochloride
Origin:
EU

Nasivin Classic (Oxymetazoline Hydrochloride)

Oxymetazoline Hydrochloride, the active ingredient in Nasivin Classic, is a alpha‑adrenergic agonist presented as a nasal spray for topical nasal use. It relieves nasal congestion in adults and children experiencing colds, allergies, or sinus pressure.

GNH India supplies Nasivin Classic as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

P&g Health Germany Gmbh

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Indications & Clinical Uses

Oxymetazoline Hydrochloride acts as a topical nasal decongestant to reduce swelling of the nasal mucosa.

  • Common cold: alleviates nasal blockage and improves airflow.
  • Allergic rhinitis: reduces congestion caused by allergic inflammation.
  • Acute sinusitis: helps clear nasal passages and eases pressure.

How It Works

  • Oxymetazoline Hydrochloride selectively stimulates alpha‑adrenergic receptors on the smooth muscle of nasal mucosal blood vessels, causing vasoconstriction. This reduces blood flow to the nasal lining, decreasing edema and mucus formation, which results in rapid relief of nasal congestion.

Side Effects

Adverse reactions may occur with nasal administration of oxymetazoline.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Dryness of the nasal mucosa.
  • Sneezing or mild itching.
  • Headache.
  • Transient taste disturbance.

Serious or Rare Side Effects

  • Rebound congestion (rhinitis medicamentosa) after prolonged use.
  • Elevated blood pressure or hypertension.
  • Tachycardia or irregular heart rhythm.
  • Severe allergic reaction (anaphylaxis).
  • Persistent nasal ulceration.

Precautions & Warnings

Use Nasivin Classic with awareness of specific safety considerations.

  • Do not exceed recommended duration: limit use to no more than three consecutive days.
  • Avoid use in children under six years: consult a pediatrician before administration.
  • Use with caution in hypertension: monitor blood pressure during treatment.
  • Avoid concurrent use with monoamine oxidase inhibitors (MAOIs): discuss with a healthcare professional.
  • Store at room temperature: keep in the original container, protect from moisture and direct heat.

Avoid Interactions

Oxymetazoline may interact with other sympathomimetic agents and cardiovascular drugs.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.
  • Other nasal decongestants: additive vasoconstriction may cause severe hypertension.
  • Systemic sympathomimetics (e.g., epinephrine): may lead to excessive cardiovascular stimulation.

Moderate Interactions (Monitor Closely):\n- Antihypertensive medications: possible reduction in blood‑pressure‑lowering effect.

  • Beta‑blockers: may blunt compensatory heart‑rate response.
  • Tricyclic antidepressants: increased likelihood of cardiovascular side effects.

Frequently Asked Questions

Nasivin Classic is an over‑the‑counter nasal spray containing oxymetazoline hydrochloride. It is used to temporarily relieve nasal congestion caused by the common cold, allergic rhinitis, or acute sinusitis by shrinking swollen blood vessels in the nasal passages.

Oxymetazoline is a selective alpha‑adrenergic agonist. When applied to the nasal mucosa it binds to alpha‑1 receptors on blood‑vessel smooth muscle, causing vasoconstriction. This reduces blood flow, decreases swelling, and opens the airway for easier breathing.

The specific dose and frequency are determined by a prescriber or according to the product label. Typically, a few sprays per nostril are used, but the exact regimen should be confirmed with a healthcare professional before use.

Safety data for oxymetazoline in pregnancy and lactation are limited. Women who are pregnant or breastfeeding should consult their physician before using Nasivin Classic to weigh potential benefits against any possible risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nasivin Classic contains oxymetazoline, a potent alpha‑adrenergic agonist that provides rapid relief. Compared with older agents like phenylephrine, oxymetazoline generally offers a longer duration of action and stronger vasoconstriction, but all decongestants share similar cautions regarding short‑term use.

Store Nasivin Classic at room temperature, ideally below 25 °C. Keep the bottle tightly closed in its original packaging, protect it from moisture and direct sunlight, and ensure it is out of reach of children.

Nasivin Classic is a nasal spray. The user tilts the head slightly forward, inserts the nozzle into a nostril, and presses the pump to deliver the recommended number of sprays. The same procedure is repeated in the other nostril if directed.

Serious risks include rebound nasal congestion (rhinitis medicamentosa) after prolonged use, significant elevation of blood pressure, tachycardia, and rare allergic reactions such as anaphylaxis. If any severe symptoms develop, discontinue use and seek medical attention promptly.

Individuals with known hypersensitivity to oxymetazoline or any component of the formulation should avoid it. It is also contraindicated in patients taking monoamine oxidase inhibitors, those with severe hypertension, and children under six years of age unless advised by a pediatrician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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