Product image of Nasofan Allergy (Fluticasone Propionate) supplied by GNH India

Nasofan Allergy

Active Ingredient:
Fluticasone Propionate
Origin:
EU

Nasofan Allergy (Fluticasone Propionate)

Fluticasone propionate, the active ingredient in Nasofan Allergy, is a corticosteroid presented as a nasal spray for intranasal use. It reduces inflammation in the nasal passages and is employed to treat allergic rhinitis and related nasal conditions in adults and children.

GNH India supplies Nasofan Allergy as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved products to meet global healthcare needs. Our distribution network ensures reliable delivery across Europe, Asia, Africa and the Americas.

Manufacturer / TM Owner

Teva Uk Limited

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Indications & Clinical Uses

  • Fluticasone propionate nasal spray is used to manage inflammatory conditions of the nasal mucosa, primarily allergic rhinitis.
  • Allergic rhinitis: alleviates nasal congestion, itching, and sneezing by reducing mucosal inflammation.
  • Seasonal allergic rhinitis: controls symptoms triggered by pollen exposure.
  • Perennial allergic rhinitis: provides year‑round relief from indoor allergen‑induced symptoms.
  • Nasal polyps: helps shrink polyp size and improve airflow when used as adjunct therapy.

How It Works

  • Fluticasone propionate binds to intracellular glucocorticoid receptors in nasal epithelial cells, forming a complex that translocates to the nucleus and interacts with glucocorticoid response elements. This interaction suppresses transcription of pro‑inflammatory cytokines such as IL‑1, IL‑6, and TNF‑α, and inhibits recruitment of eosinophils, mast cells and other inflammatory cells, leading to reduced edema and mucus production in the nasal mucosa.

Side Effects

Fluticasone propionate nasal spray may cause local and systemic adverse reactions, which are categorized by frequency.

Common Side Effects

  • Nasal irritation or burning
  • Epistaxis (nosebleeds)
  • Headache
  • Altered taste

Serious or Rare Side Effects

  • Adrenal suppression
  • Fungal infection of the nasal passages
  • Allergic reaction (including anaphylaxis)
  • Perforation of the nasal septum

Precautions & Warnings

  • When using Nasofan Allergy, consider the following precautions to ensure safe and effective therapy.
  • Pregnancy: consult a healthcare professional before use.
  • Existing nasal infections: assess risk of fungal overgrowth.
  • Long‑term therapy: monitor for signs of adrenal insufficiency.
  • Glaucoma or cataracts: use with caution and seek ophthalmologic advice.
  • Surgery involving the nose: inform the surgeon of nasal steroid use.
  • Store at room temperature: keep in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Fluticasone propionate may interact with other medicines; review the following categories.

Major Interactions (Avoid)

  • Systemic corticosteroids: may increase systemic glucocorticoid exposure.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): can raise fluticasone levels.
  • Live vaccines: nasal steroids may reduce vaccine efficacy.

Moderate Interactions (Monitor Closely)

  • Antihistamines: additive nasal dryness.
  • Decongestant nasal sprays: potential irritation when combined.
  • Azole antifungals (e.g., fluconazole): may modestly increase exposure.

Frequently Asked Questions

Nasofan Allergy is a nasal spray containing fluticasone propionate that is used to treat inflammatory nasal conditions such as allergic rhinitis and nasal polyps. It works by reducing swelling, congestion, itching and sneezing associated with these disorders, providing symptom relief for both seasonal and perennial allergies.

Fluticasone propionate is a synthetic corticosteroid that binds to glucocorticoid receptors in the cells lining the nasal passages. This binding alters gene transcription, decreasing the production of inflammatory cytokines and limiting the migration of immune cells into the nasal mucosa, which in turn reduces swelling and mucus formation.

The appropriate dose of Nasofan Allergy is determined by a qualified prescriber based on the patient’s age, severity of symptoms and clinical response. Typical regimens involve one or two sprays per nostril once daily, but exact instructions should always follow the healthcare professional’s prescription.

Safety data for fluticasone propionate nasal spray in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before starting treatment.

To place an order, visit the product page on gnhindia.com, enter the required quantity and submit the enquiry form. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nasofan Allergy (fluticasone propionate) and other intranasal corticosteroids such as mometasone furoate have similar efficacy in controlling allergic rhinitis. Fluticasone has a well‑established safety profile and once‑daily dosing, while some alternatives may offer different dosing frequencies or device designs. Choice often depends on patient preference, tolerability and prescriber experience.

Store Nasofan Allergy at room temperature, ideally below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, excessive heat and direct sunlight. Do not freeze the product, and discard any spray that appears discolored or has an abnormal odor.

Nasofan Allergy is administered as a nasal spray. The user should gently blow the nose, tilt the head slightly forward, insert the nozzle into one nostril, and press the actuator while breathing in gently through the nose. The same procedure is repeated for the other nostril if prescribed.

Serious risks, although rare, include adrenal suppression, severe nosebleeds, fungal infection of the nasal passages, allergic reactions that can progress to anaphylaxis, and perforation of the nasal septum. Patients should seek immediate medical attention if they experience unusual bleeding, persistent infections, vision changes or signs of an allergic reaction.

Nasofan Allergy should be avoided in individuals with known hypersensitivity to fluticasone propionate or any component of the formulation. It is also contraindicated in patients with active untreated fungal, viral or bacterial infections of the nasal mucosa, and in those who have had recent nasal surgery unless directed by a surgeon.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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