Nasoferm (Xylometazoline Hydrochloride)

Xylometazoline is a selective α‑adrenergic agonist. By stimulating α‑receptors on the smooth muscle of nasal mucosal blood vessels, it causes vasoconstriction, which decreases blood flow, reduces edema, and opens the nasal airway. The effect is rapid and localized, with minimal systemic absorption when used as directed.

The specific dosing regimen for Nasoferm is determined by the prescribing healthcare professional based on the patient’s age, condition, and response. Typically, one or two sprays per nostril every 8‑10 hours are used, not exceeding the maximum daily frequency indicated on the product label.

Safety data for Xylometazoline in pregnancy and lactation are limited, and the product is classified as pregnancy category unknown. Women who are pregnant, planning pregnancy, or breastfeeding should consult their physician before using Nasoferm to weigh potential benefits against any uncertain risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details, and any necessary import documentation.

Compared with phenylephrine or oxymetazoline, Xylometazoline offers a rapid onset of action and a duration of effect of up to 12 hours, allowing less frequent dosing. Its selectivity for α‑adrenergic receptors may result in a slightly lower incidence of systemic cardiovascular effects, though individual response varies.

Store Nasoferm at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, heat, and direct sunlight. Do not freeze the product, and keep it out of reach of children.

Nasoferm is applied as a nasal spray. Before use, gently blow the nose to clear passages, then insert the nozzle into one nostril while closing the opposite nostril with a finger. Press the pump to deliver the prescribed number of sprays, repeat in the other nostril if directed, and avoid blowing the nose immediately after administration.

Serious adverse events, though rare, include severe hypertension, tachycardia, arrhythmias, and rebound nasal congestion (rhinitis medicamentosa) after prolonged use. Allergic reactions such as rash, itching, swelling, or difficulty breathing also require immediate medical attention. Users should discontinue the product and seek care if any of these symptoms occur.

Nasoferm should be avoided in individuals with known hypersensitivity to Xylometazoline or any formulation components, in children under the recommended minimum age without medical advice, and in patients with severe hypertension, coronary artery disease, or uncontrolled cardiovascular disorders unless directed by a physician.