Product image of Nasogen (Xylometazoline Hydrochloride) supplied by GNH India

Nasogen

Active Ingredient:
Xylometazoline Hydrochloride
Origin:
EU

Nasogen (Xylometazoline Hydrochloride)

Xylometazoline Hydrochloride, the active ingredient in Nasogen, is an alpha-adrenergic agonist presented as a nasal spray for nasal use. It relieves nasal congestion associated with the common cold, sinusitis, and allergic rhinitis in adults and children.
GNH India supplies Nasogen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Alvogen Ehf

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Indications & Clinical Uses

  • Nasogen, an alpha‑adrenergic nasal decongestant, is used to alleviate congestion in several upper‑respiratory conditions.
  • Common cold nasal congestion: reduces mucosal swelling to improve airflow.
  • Sinusitis-associated congestion: decreases edema of the sinus passages.
  • Allergic rhinitis: eases nasal blockage caused by allergic inflammation.

How It Works

  • Xylometazoline Hydrochloride acts as a selective alpha‑adrenergic receptor agonist on the vascular smooth muscle of the nasal mucosa. Activation of these receptors induces vasoconstriction, which diminishes blood flow, reduces mucosal edema, and opens the nasal airway, providing rapid decongestion.

Side Effects

Adverse reactions may occur with nasal administration of Xylometazoline Hydrochloride.

Common Side Effects

  • Nasal burning or stinging sensation
  • Dryness of the nasal mucosa
  • Sneezing
  • Headache
  • Altered taste or smell
  • Mild epistaxis

Serious or Rare Side Effects

  • Rebound nasal congestion with prolonged use
  • Severe hypertension or tachycardia
  • Nasal ulceration or septal perforation
  • Allergic reaction (rash, itching, swelling)
  • Cardiac arrhythmia
  • Vision disturbances

Precautions & Warnings

  • Before using Nasogen, consider the following safety measures.
  • Use duration: limit use to 3‑5 consecutive days to avoid rebound congestion.
  • Age restrictions: not recommended for children under 2 years unless directed by a clinician.
  • Pregnancy: consult a healthcare professional before use.
  • Cardiovascular disease: use with caution in patients with hypertension or heart disease.
  • Concurrent nasal decongestants: avoid simultaneous use of other topical decongestants.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Xylometazoline may interact with other medications that affect vascular tone or blood pressure.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): increased risk of hypertensive crisis.
  • Other nasal decongestants: additive vasoconstrictive effects.
  • Systemic sympathomimetics: excessive cardiovascular stimulation.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: possible reduction in blood‑pressure‑lowering effect.
  • Beta‑blockers: monitor for changes in heart rate or blood pressure.

Frequently Asked Questions

Nasogen contains Xylometazoline Hydrochloride and is used as an over‑the‑counter nasal decongestant to temporarily relieve nasal blockage caused by the common cold, sinusitis, or allergic rhinitis.

Xylometazoline Hydrochloride selectively stimulates alpha‑adrenergic receptors on the blood vessels of the nasal mucosa, causing vasoconstriction. This reduces swelling and opens the nasal passages, providing rapid relief of congestion.

The appropriate dose and frequency are determined by a healthcare professional based on the patient’s age, condition, and response. Users should follow the prescriber’s instructions and the product label.

Safety data for Xylometazoline Hydrochloride in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should consult their healthcare provider before using Nasogen.

To request Nasogen, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nasogen’s active ingredient, Xylometazoline, is an alpha‑adrenergic agonist similar to phenylephrine or oxymetazoline. All provide short‑term relief, but Xylometazoline has a rapid onset and is often preferred for its efficacy in both viral and allergic congestion. Choice depends on individual response and physician recommendation.

Store Nasogen at room temperature, below 25 °C. Keep the bottle tightly closed in its original packaging, protect it from moisture and direct sunlight, and avoid freezing.

Nasogen is applied intranasally as a spray. The patient tilts the head slightly forward, inserts the nozzle into one nostril, and sprays the recommended number of sprays while breathing in gently. The process is repeated in the other nostril if directed.

Serious risks include rebound nasal congestion if used longer than recommended, severe hypertension, cardiac arrhythmias, nasal ulceration or septal perforation, and allergic reactions such as rash or swelling. Any of these symptoms require immediate medical attention.

Nasogen should be avoided by individuals with known hypersensitivity to Xylometazoline or any formulation ingredients, patients with severe hypertension, coronary artery disease, or uncontrolled cardiovascular conditions, and children under the age specified on the label unless advised by a clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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