Product image of Nasomaris 1 Mg/Ml (Xylometazoline Hydrochloride) supplied by GNH India

Nasomaris 1 Mg/Ml

Active Ingredient:
Xylometazoline Hydrochloride
Origin:
EU

Nasomaris 1 Mg/Ml (Xylometazoline Hydrochloride)

Xylometazoline Hydrochloride, the active ingredient in Nasomaris 1 Mg/Ml, is a topical nasal decongestant presented as a 1 mg/mL nasal spray solution for nasal use. It relieves nasal congestion associated with the common cold, sinusitis and allergic rhinitis in adults and children.

GNH India supplies Nasomaris 1 Mg/Ml as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Jadran-Galenski Laboratorij D.D.

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Indications & Clinical Uses

Xylometazoline Hydrochloride is a topical alpha‑adrenergic nasal decongestant used to reduce swelling of the nasal mucosa.

  • Common cold: reduces nasal blockage and improves breathing.
  • Sinusitis: alleviates congestion linked to sinus inflammation.
  • Allergic rhinitis: decreases nasal swelling caused by allergen exposure.

How It Works

  • Xylometazoline Hydrochloride selectively stimulates alpha‑adrenergic receptors on the vascular smooth muscle of the nasal mucosa. This activation causes vasoconstriction, which reduces blood flow to the swollen mucosal tissue, leading to decreased edema and improved airway patency. The localized effect limits systemic absorption, providing rapid relief of nasal congestion.

Side Effects

Adverse reactions may occur with nasal application of Xylometazoline Hydrochloride.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Dryness of the nasal passages.
  • Sneezing or mild epistaxis.
  • Altered taste or bitter after‑taste.
  • Headache.
  • Transient dizziness.

Serious or Rare Side Effects

  • Severe nasal bleeding.
  • Allergic reactions such as rash, itching or anaphylaxis.
  • Hypertension or marked increase in blood pressure.
  • Tachycardia or palpitations.
  • Rebound congestion (rhinitis medicamentosa) after prolonged use.
  • Vision disturbances.

Precautions & Warnings

Before using Nasomaris, consider the following safety measures.

  • Age restriction: avoid use in children under 6 years unless directed by a healthcare professional.
  • Pregnancy: safety not established; consult a physician before use.
  • Cardiovascular disease: use with caution in patients with hypertension or heart disease.
  • Concomitant decongestants: do not combine with other nasal or oral decongestants to prevent excess vasoconstriction.
  • Duration of therapy: limit use to 3‑5 days to avoid rebound congestion.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Xylometazoline may interact with other medicines; monitor as indicated.

Major Interactions (Avoid)

  • MAO inhibitors: risk of hypertensive crisis due to additive vasoconstriction.
  • Systemic sympathomimetics (e.g., pseudoephedrine): may cause excessive cardiovascular stimulation.
  • Beta‑blockers: can blunt the intended vasoconstrictive response.

Moderate Interactions (Monitor Closely):\n- Antihypertensive agents: nasal decongestant may reduce their effectiveness.

  • Tricyclic antidepressants: possible additive cardiovascular effects.
  • Other nasal sprays (e.g., steroids): monitor for local irritation or increased systemic absorption.

Frequently Asked Questions

Nasomaris 1 Mg/Ml is a nasal spray containing Xylometazoline Hydrochloride, indicated for the temporary relief of nasal congestion caused by the common cold, sinusitis, and allergic rhinitis. It works locally in the nasal passages to reduce swelling and improve airflow.

Xylometazoline Hydrochloride is a selective alpha‑adrenergic agonist. By binding to alpha‑receptors on the blood vessels of the nasal mucosa, it causes vasoconstriction, which decreases blood flow, reduces mucosal edema, and opens the nasal airway.

The specific dosing regimen for Nasomaris 1 Mg/Ml is determined by the prescribing healthcare professional. Typically, the product is administered as a few sprays into each nostril, but the exact number of sprays and frequency should follow the prescriber’s instructions.

Safety data for Xylometazoline Hydrochloride in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Nasomaris.

To place an order, visit the product page on gnhindia.com, submit an enquiry with the required quantity, and provide institutional or trade credentials. GNH India’s team will respond with pricing, availability, shipping details (including any cold‑chain requirements), and the necessary import documentation.

Nasomaris contains Xylometazoline, an alpha‑adrenergic agonist similar to oxymetazoline. Both provide rapid relief of congestion, but Xylometazoline may have a slightly longer duration of action. Choice between products often depends on clinician preference, patient tolerance, and local availability.

Nasomaris should be stored at room temperature, below 25 °C, in its original packaging. Keep the bottle tightly closed, protect it from moisture and direct sunlight, and avoid freezing. Do not use the product after the expiration date printed on the label.

Nasomaris is a nasal spray solution. The user tilts the head slightly forward, inserts the nozzle into a nostril, and depresses the pump to deliver the recommended number of sprays. The same procedure is repeated for the other nostril if instructed by the prescriber.

Serious risks, though uncommon, include severe nasal bleeding, allergic reactions such as rash or anaphylaxis, marked hypertension, tachycardia, and rebound congestion (rhinitis medicamentosa) after prolonged use. Any signs of these reactions require immediate medical attention.

Nasomaris should be avoided in individuals with known hypersensitivity to Xylometazoline or any excipients, in children under 6 years unless directed by a physician, and in patients with uncontrolled hypertension, severe cardiovascular disease, or those already using other nasal decongestants.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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