Product image of Nasonex (Mometasone Furoate) supplied by GNH India

Nasonex

Active Ingredient:
Mometasone Furoate
Origin:
EU

Nasonex (Mometasone Furoate)

Mometasone furoate, the active ingredient in Nasonex, is a corticosteroid presented as a nasal spray for intranasal use. It is formulated to relieve symptoms of allergic rhinitis, seasonal and perennial, as well as to manage nasal polyps by decreasing mucosal inflammation and edema within the nasal cavity.

GNH India supplies Nasonex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality and regulatory conformity across global markets. The company utilizes validated manufacturing processes and secure distribution channels to maintain product integrity during transit.

Manufacturer / TM Owner

N.V. Organon

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Nasonex (mometasone furoate) is a corticosteroid nasal spray used to treat inflammatory conditions of the nasal passages.
  • Allergic rhinitis: reduces nasal congestion, itching, and sneezing associated with allergic triggers.
  • Seasonal allergic rhinitis: provides symptom relief during pollen or seasonal allergen exposure.
  • Perennial allergic rhinitis: controls year‑round nasal inflammation caused by indoor allergens.
  • Nasal polyps: decreases polyp size and improves nasal airflow and breathing.

How It Works

  • Mometasone furoate binds to intracellular glucocorticoid receptors in nasal mucosal cells, forming a complex that translocates to the nucleus and modulates gene transcription. This action suppresses the production of pro‑inflammatory cytokines, chemokines, and adhesion molecules, while enhancing anti‑inflammatory proteins, leading to reduced vascular permeability, edema, and cellular infiltration in the nasal lining. The localized effect minimizes systemic exposure and maintains a favorable safety profile.

Side Effects

Mometasone furoate nasal spray may cause local and, rarely, systemic adverse reactions.

Common Side Effects

  • Nasal irritation or burning sensation
  • Epistaxis (nosebleed)
  • Headache
  • Sore throat
  • Cough
  • Altered taste or bitter aftertaste

Serious or Rare Side Effects

  • Adrenal suppression with prolonged use
  • Increased intraocular pressure or glaucoma
  • Cataract formation
  • Fungal sinusitis or secondary infection
  • Severe allergic reaction (anaphylaxis)
  • Nasal septal perforation

Precautions & Warnings

  • When prescribing Nasonex, consider the following precautions.
  • Assess patient history: evaluate for recent nasal surgery or trauma.
  • Avoid use in active infections: do not use if nasal or sinus infection is present without physician guidance.
  • Monitor for systemic effects: watch for signs of cortisol suppression during long‑term therapy.
  • Caution in glaucoma patients: may increase intraocular pressure.
  • Pregnancy and lactation: use only if benefit outweighs risk after medical assessment.
  • Store at room temperature: keep below 25 °C, protect from moisture and direct sunlight.

Avoid Interactions

Mometasone furoate nasal spray can interact with other medicines; review patient medication lists.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors: may increase systemic exposure of mometasone.
  • Systemic corticosteroids: additive glucocorticoid effects, risk of adrenal suppression.

Moderate Interactions (Monitor Closely)

  • Antifungal azoles (ketoconazole, itraconazole): may modestly raise mometasone levels.
  • Protease inhibitors such as ritonavir: potential increase in exposure.
  • Live vaccines: efficacy may be reduced if systemic absorption occurs.

Frequently Asked Questions

Nasonex (mometasone furoate) is indicated for the treatment of allergic rhinitis, both seasonal and perennial forms, and for the management of nasal polyps. It works by reducing inflammation within the nasal passages, helping to relieve congestion, sneezing, itching, and nasal obstruction associated with these conditions.

Mometasone furoate binds to glucocorticoid receptors in the cells lining the nasal mucosa. This binding alters gene transcription, suppressing the release of inflammatory cytokines and mediators while enhancing anti‑inflammatory proteins. The result is reduced swelling, mucus production, and vascular permeability, which alleviates nasal symptoms.

The exact dosing regimen for Nasonex is determined by the prescribing clinician based on the patient’s age, severity of symptoms, and clinical response. In many adult cases, the typical regimen involves one spray into each nostril once daily, but the prescriber may adjust frequency or amount as needed.

Safety data for mometasone furoate in pregnancy and lactation are limited. The medication should be used during pregnancy only if the potential benefit justifies any potential risk to the fetus, and breastfeeding mothers should consult their healthcare provider to weigh benefits against possible exposure to the infant.

To order Nasonex, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and assist with import documentation.

Nasonex contains mometasone furoate, which has a high receptor affinity and low systemic bioavailability, similar to other intranasal steroids such as fluticasone propionate and budesonide. Clinical studies suggest comparable efficacy in relieving allergic rhinitis symptoms, while the once‑daily dosing schedule of Nasonex may offer convenience for some patients.

Store Nasonex at room temperature, below 25 °C (77 °F). Keep the bottle in its original packaging, protect it from moisture and direct sunlight, and ensure the spray tip remains clean. Do not freeze the product, and keep it out of reach of children.

Before use, gently shake the bottle and prime the spray by pressing the actuator several times until a fine mist appears. Tilt the head slightly forward, insert the tip into one nostril, close the opposite nostril with a finger, and press the actuator while breathing in gently. Repeat in the other nostril if prescribed.

Serious but rare risks include adrenal suppression, especially with prolonged high‑dose use, increased intraocular pressure that may lead to glaucoma, cataract formation, and severe allergic reactions such as anaphylaxis. Patients should report persistent nosebleeds, visual changes, or signs of systemic corticosteroid effects to their healthcare provider promptly.

Nasonex should be avoided in individuals with known hypersensitivity to mometasone furoate or any component of the formulation. It is also contraindicated in patients with active untreated nasal or sinus infections, recent nasal surgery or trauma, and in those for whom systemic corticosteroid therapy is contraindicated without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.