Product image of Nasoxyl Paediatric (Xylometazoline Hydrochloride) supplied by GNH India

Nasoxyl Paediatric

Active Ingredient:
Xylometazoline Hydrochloride
Origin:
EU

Nasoxyl Paediatric (Xylometazoline Hydrochloride)

Xylometazoline Hydrochloride, the active ingredient in Nasoxyl Paediatric, is an imidazoline nasal decongestant presented as a nasal spray for nasal use. It relieves nasal congestion associated with common cold, sinusitis and allergic rhinitis in children.

GNH India supplies Nasoxyl Paediatric as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sapiens Pharmaceuticals Ltd

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Indications & Clinical Uses

Xylometazoline Hydrochloride is an imidazoline nasal decongestant used to alleviate upper‑respiratory tract congestion in children.

  • Common cold: reduces nasal blockage and improves breathing.
  • Sinusitis: decreases mucosal swelling to facilitate sinus drainage.
  • Allergic rhinitis: alleviates congestion caused by allergen‑induced inflammation.

How It Works

  • Xylometazoline Hydrochloride acts as a selective alpha‑adrenergic receptor agonist on the vascular smooth muscle of the nasal mucosa. By stimulating these receptors, it induces vasoconstriction, which reduces blood flow, limits edema, and opens the nasal airway, providing rapid relief of congestion.

Side Effects

Nasal decongestant sprays may cause local and systemic reactions.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Dryness of the nasal mucosa.
  • Sneezing.
  • Headache.
  • Altered taste perception.
  • Mild epistaxis.

Serious or Rare Side Effects

  • Persistent nasal bleeding.
  • Severe allergic reaction (anaphylaxis).
  • Rebound congestion (rhinitis medicamentosa) after prolonged use.

Precautions & Warnings

Use Nasoxyl Paediatric with attention to specific safety considerations.

  • Age restriction: not for children under 2 years unless advised by a healthcare professional.
  • Duration of use: limit to 3‑5 days to avoid rebound congestion.
  • Existing nasal conditions: avoid if nasal ulceration or severe trauma is present.
  • Concurrent MAO inhibitors: use with caution due to potential cardiovascular effects.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Xylometazoline may interact with other sympathomimetic agents.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may increase hypertensive risk.
  • Other nasal decongestants: additive vasoconstriction can raise blood pressure.
  • Sympathomimetic drugs: risk of excessive cardiovascular stimulation.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may blunt tachycardia response.
  • Antihypertensive agents: monitor blood pressure for changes.
  • Corticosteroid nasal sprays: assess for increased local irritation.

Frequently Asked Questions

Nasoxyl Paediatric is a nasal spray containing Xylometazoline Hydrochloride that provides temporary relief of nasal congestion in children caused by common colds, sinusitis, or allergic rhinitis.

Xylometazoline Hydrochloride selectively stimulates alpha‑adrenergic receptors on nasal blood vessels, causing vasoconstriction. This reduces swelling of the nasal mucosa, opens the airway and eases breathing.

The appropriate dose and frequency are determined by a qualified prescriber based on the child’s age, weight and clinical condition. Patients should follow the healthcare professional’s instructions.

Safety data for Xylometazoline Hydrochloride in pregnancy and lactation are limited. Women who are pregnant or breastfeeding should consult their healthcare provider before using the product.

Enquiries can be submitted on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Nasoxyl Paediatric contains Xylometazoline, an imidazoline‑type decongestant, which typically provides rapid onset of action. Compared with phenylephrine‑based sprays, Xylometazoline often has a longer duration of relief but shares similar safety considerations regarding short‑term use.

Store the spray at room temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight and extreme temperatures to maintain product stability.

The product is a nasal spray intended for intranasal use. The prescriber will advise the number of sprays per nostril and the interval between doses, typically not exceeding the recommended short‑term duration.

Serious risks include persistent nasal bleeding, severe allergic reactions such as anaphylaxis, and rebound congestion (rhinitis medicamentosa) if used beyond the recommended period.

Children under 2 years of age, individuals with known hypersensitivity to Xylometazoline or any formulation component, and patients with severe nasal ulceration or trauma should avoid using this product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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