Product image of Nasoxylin (Oxymetazoline Hydrochloride) supplied by GNH India

Nasoxylin

Active Ingredient:
Oxymetazoline Hydrochloride
Origin:
EU

Nasoxylin (Oxymetazoline Hydrochloride)

Oxymetazoline Hydrochloride, the active ingredient in Nasoxylin, is an alpha‑adrenergic agonist presented as a nasal spray for intranasal use. It relieves nasal congestion caused by the common cold, sinusitis, and allergic rhinitis in adults and children.

GNH India supplies Nasoxylin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Pannonpharma Kft.

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Indications & Clinical Uses

Oxymetazoline Hydrochloride acts on nasal vascular tone to reduce swelling and improve airflow.

  • Common cold: alleviates nasal congestion and improves breathing.
  • Sinusitis: decreases mucosal edema to facilitate sinus drainage.
  • Allergic rhinitis: reduces nasal blockage associated with allergic inflammation.

How It Works

  • Oxymetazoline Hydrochloride selectively stimulates α‑adrenergic receptors on the smooth muscle of nasal mucosal blood vessels. This activation causes vasoconstriction, which diminishes blood flow, reduces edema, and opens the nasal passages, thereby relieving congestion.

Side Effects

Adverse reactions may occur with intranasal oxymetazoline use.

Common Side Effects

  • Nasal irritation or burning sensation.
  • Dryness of the nasal mucosa.
  • Sneezing or mild itching.
  • Headache.
  • Transient taste disturbance.

Serious or Rare Side Effects

  • Rebound nasal congestion with prolonged use.
  • Elevated blood pressure or hypertension.
  • Tachycardia or arrhythmia.
  • Severe nasal ulceration or epistaxis.
  • Allergic reaction such as rash or angioedema.

Precautions & Warnings

Before using Nasoxylin, consider the following safety measures.

  • Duration limit: do not exceed 3‑5 consecutive days of use to avoid rebound congestion.
  • Cardiovascular disease: avoid if you have uncontrolled hypertension or heart disease.
  • MAO inhibitor therapy: contraindicated due to risk of hypertensive crisis.
  • Pediatric use: not recommended for children under 6 years without medical advice.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Store at ambient temperature: keep below 25 °C, in the original container, protected from moisture and direct sunlight.

Avoid Interactions

Oxymetazoline may interact with other medicines that affect vascular tone or blood pressure.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): risk of severe hypertension.
  • Other topical nasal decongestants: additive vasoconstriction leading to rebound congestion.

Moderate Interactions (Monitor Closely):\n- Oral sympathomimetic decongestants (e.g., pseudoephedrine): may increase cardiovascular effects.

  • Antihypertensive agents (beta‑blockers, ACE inhibitors): monitor blood pressure.
  • Tricyclic antidepressants: potential for additive adrenergic activity.

Frequently Asked Questions

Nasoxylin contains oxymetazoline hydrochloride and is used to temporarily relieve nasal congestion caused by the common cold, sinusitis, or allergic rhinitis. It works by narrowing blood vessels in the nasal passages, which reduces swelling and improves airflow.

Oxymetazoline hydrochloride is a selective alpha‑adrenergic agonist. When applied to the nasal mucosa, it stimulates alpha receptors on blood‑vessel smooth muscle, causing vasoconstriction. This reduces mucosal edema and opens the nasal airway, providing rapid decongestion.

The appropriate dose of Nasoxylin is determined by a qualified healthcare professional based on the patient’s age, condition, and response. Users should follow the prescriber’s instructions and not exceed the recommended duration of use.

Safety data for oxymetazoline during pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare provider before using Nasoxylin to weigh potential benefits against risks.

To order Nasoxylin, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nasoxylin’s active ingredient, oxymetazoline, provides rapid, long‑lasting decongestion compared with some short‑acting agents like phenylephrine. However, all topical decongestants share a risk of rebound congestion if used beyond the recommended 3‑5‑day limit.

Store Nasoxylin at ambient temperature, below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight, and extreme heat. Ensure the cap is tightly closed to maintain product integrity.

Nasoxylin is administered intranasally. The user sprays the recommended number of sprays into each nostril as directed by a healthcare professional, typically while the head is upright, and avoids blowing the nose immediately after application.

Serious risks include rebound nasal congestion with prolonged use, significant elevation of blood pressure, tachycardia, and rare allergic reactions such as rash or angioedema. Patients should discontinue use and seek medical attention if these symptoms occur.

Nasoxylin should not be used by individuals with known hypersensitivity to oxymetazoline or any formulation components, those taking monoamine oxidase inhibitors, patients with severe hypertension, or children under six years of age unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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