Product image of Natecal D3 (Colecalciferol, Calcium Carbonate) supplied by GNH India

Natecal D3

Active Ingredient:
Colecalciferol, Calcium Carbonate
Origin:
EU

Natecal D3 (Colecalciferol, Calcium Carbonate)

Colecalciferol and Calcium Carbonate, the active ingredients in Natecal D3, are a Vitamin D3 and Calcium supplement presented as an oral nutritional supplement for oral use. They help prevent vitamin D and calcium deficiency and support bone health in adults and children.

GNH India supplies Natecal D3 as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Itf Hellas S.A.

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Indications & Clinical Uses

Natecal D3 is used to address deficiencies in the vitamin D and calcium pathways.

  • Vitamin D deficiency: helps restore adequate vitamin D levels and supports calcium metabolism.
  • Calcium deficiency: provides calcium carbonate to increase calcium intake and promote bone mineralization.
  • Bone health support: contributes to maintaining normal bone density and reducing risk of fractures in at‑risk populations.

How It Works

  • Colecalciferol is metabolized in the liver to 25‑hydroxyvitamin D and then in the kidney to the active hormone calcitriol, which binds to vitamin D receptors and up‑regulates intestinal calcium‑binding proteins, enhancing calcium and phosphate absorption. Calcium carbonate supplies elemental calcium that is incorporated into the hydroxyapatite matrix of bone, together facilitating bone mineralization and remodeling.

Side Effects

Natecal D3 may cause adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea or mild stomach upset.
  • Constipation or flatulence.
  • Mild headache.
  • Transient hypercalcemia symptoms such as mild fatigue.

Serious or Rare Side Effects

  • Severe hypercalcemia leading to arrhythmias or renal impairment.
  • Kidney stone formation.
  • Allergic reactions including rash, itching, or swelling of the face and throat.
  • Hypervitaminosis D with prolonged excessive dosing.

Precautions & Warnings

Before using Natecal D3, consider the following precautions.

  • Pregnancy: consult a healthcare professional before use.
  • Renal impairment: monitor serum calcium and vitamin D levels.
  • Hypercalcemia risk: avoid concurrent high‑dose calcium or vitamin D supplements.
  • Drug interactions: review all concomitant medications with a clinician.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct heat.

Avoid Interactions

Natecal D3 can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Thiazide diuretics: may increase calcium retention and risk of hypercalcemia.
  • High‑dose vitamin A supplements: combined excess can precipitate hypercalcemia.

Moderate Interactions (Monitor Closely)

  • Orlistat: may reduce absorption of fat‑soluble vitamin D.
  • Glucocorticoids: can impair calcium balance and bone health.
  • Anticonvulsants (e.g., phenytoin, phenobarbital): may increase vitamin D metabolism, reducing efficacy.

Frequently Asked Questions

Natecal D3 is a nutritional supplement containing vitamin D3 (colecalciferol) and calcium carbonate. It is indicated to prevent vitamin D deficiency, prevent calcium deficiency, and support overall bone health in both adults and children.

Colecalciferol is converted in the liver to 25‑hydroxyvitamin D and then in the kidney to the active hormone calcitriol. Calcitriol binds to vitamin D receptors, increasing transcription of calcium‑binding proteins and enhancing intestinal absorption of calcium and phosphate, which are essential for bone mineralization.

The specific dose of Natecal D3 is determined by the prescribing healthcare professional based on the individual’s age, nutritional status, laboratory values and clinical needs. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

Safety in pregnancy and lactation has not been fully established; therefore, use should be discussed with a qualified healthcare provider. The prescriber will weigh potential benefits against any theoretical risks before recommending the supplement.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Natecal D3 combines both colecalciferol and calcium carbonate in a single oral formulation, whereas many alternatives provide only vitamin D or calcium alone. This dual composition may simplify dosing for patients needing both nutrients, but clinicians should compare potency, elemental calcium content and regulatory status when selecting a product.

Natecal D3 should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture, direct sunlight and excessive heat to maintain product stability throughout its shelf life.

The product is taken orally, usually with food or a glass of water, as directed by the prescribing clinician. Swallow tablets or capsules whole; do not crush or chew unless the formulation specifically allows it.

The most serious adverse reactions include hypercalcemia, which may present with nausea, vomiting, weakness, and cardiac arrhythmias, and rare allergic responses such as rash, itching or swelling. Patients experiencing these symptoms should seek medical attention promptly.

Individuals with known hypersensitivity to colecalciferol, calcium carbonate or any excipients, as well as patients with severe hypercalcemia, hypervitaminosis D, or certain renal disorders, should avoid using this supplement unless a healthcare professional advises otherwise.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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