Product image of Natecal D3 (Colecalciferol, Calcium Carbonate) supplied by GNH India

Natecal D3

Active Ingredient:
Colecalciferol, Calcium Carbonate
Origin:
EU

Natecal D3 (Colecalciferol, Calcium Carbonate)

Colecalciferol, the active ingredient in Natecal D3, is a vitamin D3 supplement presented as an oral dosage form for oral use. It supports calcium metabolism and bone health in individuals with vitamin D or calcium deficiency.

GNH India supplies Natecal D3 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Chiesi Limited

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Natecal D3 provides vitamin D3 and calcium carbonate to address disorders of mineral metabolism and bone integrity.

  • Vitamin D deficiency: restores adequate serum 25‑hydroxyvitamin D levels.
  • Calcium deficiency: supplies elemental calcium to maintain normal serum calcium.
  • Osteomalacia: aids mineralisation of bone matrix in adults.
  • Osteoporosis prevention: contributes to bone density maintenance when combined with other therapies.
  • Hypocalcaemia secondary to hypoparathyroidism: helps raise low calcium concentrations.

How It Works

  • Colecalciferol (vitamin D3) is converted in the liver to 25‑hydroxyvitamin D and then in the kidney to the active hormone calcitriol, which binds the vitamin D receptor and enhances intestinal absorption of calcium and phosphate. Calcium carbonate provides elemental calcium that is released in the acidic gastric environment, adding directly to the calcium pool and working synergistically with calcitriol‑mediated absorption to improve bone mineralisation.

Side Effects

Natecal D3 may cause adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Hypercalcaemia: elevated serum calcium causing fatigue or mild nausea.
  • Nausea or vomiting.
  • Constipation or abdominal discomfort.
  • Headache.
  • Dry mouth.
  • Metallic taste.

Serious or Rare Side Effects

  • Severe hypercalcaemia leading to renal stones or cardiac arrhythmia.
  • Hypervitaminosis D with symptoms such as polyuria, polydipsia, and confusion.
  • Allergic reactions: rash, pruritus, or angio‑edema.
  • Pancreatitis associated with excessive calcium levels.
  • Hypercalcaemic crisis requiring emergency medical care.

Precautions & Warnings

Before initiating therapy with Natecal D3, consider the following safety measures.

  • Baseline assessment: check serum calcium, phosphate and 25‑hydroxyvitamin D levels.
  • Renal function: monitor kidney function in patients with chronic kidney disease.
  • Hypercalcaemia: avoid use in individuals with existing high calcium concentrations.
  • Sarcoidosis or granulomatous disease: use with caution as vitamin D activation may be increased.
  • Concomitant calcium supplements: assess total calcium intake to prevent excess.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Natecal D3 can influence or be influenced by other medicines; interaction severity varies.

Major Interactions (Avoid)

  • Thiazide diuretics: may exacerbate hypercalcaemia.
  • High‑dose vitamin A: increases risk of hypervitaminosis D.
  • Lithium: can alter calcium metabolism.

Moderate Interactions (Monitor Closely)

  • Orlistat: reduces absorption of fat‑soluble vitamins including vitamin D.
  • Antacids containing aluminium or magnesium: may decrease calcium carbonate absorption.
  • Corticosteroids: can diminish calcium absorption and increase bone loss risk.

Frequently Asked Questions

Natecal D3 is a combined oral supplement of colecalciferol (vitamin D3) and calcium carbonate. It is used to correct vitamin D and calcium deficiencies, support bone health, and manage conditions such as osteomalacia, osteoporosis prevention, and hypocalcaemia when prescribed by a healthcare professional.

Colecalciferol is converted first to 25‑hydroxyvitamin D in the liver and then to the active hormone calcitriol in the kidneys. Calcitriol binds to the vitamin D receptor, stimulating intestinal absorption of calcium and phosphate, which are essential for bone mineralisation and overall calcium homeostasis.

The appropriate dose of Natecal D3 is determined by the prescribing clinician based on the patient’s serum vitamin D level, calcium status, age, and underlying medical conditions. Dosage may vary from low maintenance doses to higher therapeutic regimens, and patients should follow the prescriber’s instructions exactly.

Vitamin D and calcium are important during pregnancy and lactation, but the safety of Natecal D3 should be evaluated by a healthcare provider. The prescriber will consider the mother’s nutritional status and any potential risk of excess calcium or vitamin D before recommending the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Natecal D3 combines vitamin D3 with calcium carbonate, offering both the hormonal component for calcium absorption and a direct source of elemental calcium. Single‑ingredient vitamin D products provide only the hormonal effect, so Natecal D3 may be preferred when simultaneous calcium supplementation is clinically indicated.

Store Natecal D3 at room temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability throughout its shelf life.

Natecal D3 is taken orally, usually with food to improve calcium carbonate absorption. The tablet should be swallowed whole with a glass of water unless the prescriber provides an alternative administration instruction.

The most serious risks include severe hypercalcaemia, which can lead to kidney stones, cardiac arrhythmias, or pancreatitis, and hypervitaminosis D, which may cause neurological symptoms and renal impairment. Patients should be monitored for signs of excess calcium or vitamin D and report any unusual symptoms promptly.

Natecal D3 should be avoided in individuals with known hypercalcaemia, severe renal impairment, active sarcoidosis or other granulomatous diseases, and in patients who are already receiving high doses of calcium or vitamin D unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Colecalciferol, Calcium Carbonate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT