Product image of Natecal Vitamine D3 (Colecalciferol, Calcium Carbonate) supplied by GNH India

Natecal Vitamine D3

Active Ingredient:
Colecalciferol, Calcium Carbonate
Origin:
EU

Natecal Vitamine D3 (Colecalciferol, Calcium Carbonate)

Colecalciferol, the active ingredient in Natecal Vitamine D3, is a Vitamin D3 (Colecalciferol) and Calcium supplement presented as an oral tablet for oral use. It helps prevent vitamin D deficiency and supports calcium intake for bone health in adults and children.

GNH India supplies Natecal Vitamine D3 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company ensures quality manufacturing in accordance with EU standards.

Manufacturer / TM Owner

Effik

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Indications & Clinical Uses

Natecal Vitamine D3 is used to address nutritional deficiencies related to vitamin D and calcium, supporting skeletal health.

  • Vitamin D deficiency: helps restore adequate vitamin D levels, promoting normal calcium absorption and bone metabolism.
  • Osteopenia or low bone mass: provides calcium to aid bone mineralization and reduce risk of bone loss.
  • Growth and development in children: supplies essential calcium and vitamin D for proper skeletal development and maintenance.

How It Works

  • Colecalciferol (vitamin D3) is absorbed in the intestine and converted in the liver and kidneys to the active hormone calcitriol, which binds to vitamin D receptors and enhances transcription of calcium‑transport proteins, increasing intestinal calcium absorption. Calcium carbonate dissociates in the acidic stomach environment, releasing elemental calcium that contributes directly to bone mineralization and systemic calcium balance.

Side Effects

Natecal Vitamine D3 may cause adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea: mild stomach upset after ingestion.
  • Constipation: reduced bowel movements.
  • Abdominal discomfort: cramping or bloating.
  • Flatulence: increased gas production.
  • Mild hypercalcemia symptoms: fatigue or thirst.

Serious or Rare Side Effects

  • Severe hypercalcemia: confusion, cardiac arrhythmia, or renal impairment.
  • Kidney stones: calcium deposition in the urinary tract.
  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Hypervitaminosis D: excessive vitamin D levels leading to tissue calcification.
  • Anaphylaxis: rare but life‑threatening systemic allergic response.

Precautions & Warnings

Before using Natecal Vitamine D3, consider the following safety measures.

  • Baseline assessment: evaluate serum vitamin D and calcium levels.
  • Monitor renal function: avoid excess calcium in patients with kidney disease.
  • Avoid excessive intake: do not combine with other high‑dose vitamin D or calcium supplements.
  • Pregnancy and lactation: use only if prescribed after risk‑benefit evaluation.
  • Known hypersensitivity: discontinue if allergic reactions occur.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Natecal Vitamine D3 can interact with several medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Thiazide diuretics: may increase calcium retention leading to hypercalcemia.
  • Calcium‑containing antacids: can cause excessive calcium load.
  • High‑dose vitamin A supplements: risk of hypervitaminosis D.
  • Certain anticonvulsants (e.g., phenytoin, phenobarbital): accelerate vitamin D metabolism, reducing efficacy.
  • Sarcoidosis or granulomatous diseases: heightened conversion of vitamin D to active form.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: may increase calcium excretion, requiring monitoring.
  • Corticosteroids: can impair vitamin D metabolism, necessitating dose adjustment.
  • ACE inhibitors: occasional alterations in calcium handling.
  • Statins: rare reports of altered vitamin D levels.
  • Bisphosphonates: concurrent use may affect calcium balance.

Frequently Asked Questions

Natecal Vitamine D3 is a nutritional supplement that combines colecalciferol (vitamin D3) with calcium carbonate. It is intended to prevent vitamin D deficiency, provide calcium for bone mineralization, and support overall skeletal health in both adults and children.

Colecalciferol is absorbed from the gastrointestinal tract and converted in the liver and kidneys to calcitriol, the active form of vitamin D. Calcitriol binds to vitamin D receptors, stimulating the expression of calcium‑transport proteins in the intestine, which enhances calcium absorption and promotes bone mineralization.

The appropriate dose of Natecal Vitamine D3 is determined by a qualified health‑care professional based on the individual’s age, baseline vitamin D status, calcium needs, and any underlying medical conditions. Patients should follow the prescriber’s instructions and not self‑adjust the dosage.

Safety data for Natecal Vitamine D3 in pregnancy and lactation are limited. It should only be used during pregnancy or while breastfeeding if a health‑care provider deems the potential benefits outweigh any possible risks. Women should discuss use with their physician before starting the supplement.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide. After submission, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any cold‑chain requirements), and assist with import documentation.

Natecal Vitamine D3 combines vitamin D3 (colecalciferol) with calcium carbonate, offering both vitamin D and calcium in a single product. Stand‑alone vitamin D3 supplements provide only the vitamin, while separate calcium tablets lack vitamin D. The combined formulation can simplify dosing for patients who need both nutrients, but clinicians may prefer separate products when precise titration of each component is required.

Store Natecal Vitamine D3 at ambient temperature, preferably below 25 °C. Keep the tablets in the original packaging, protect them from moisture, direct sunlight, and excessive heat. Do not store in bathrooms or near kitchen sinks where humidity is high.

Natecal Vitamine D3 is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with a meal that contains some fat may improve absorption of the vitamin D component.

The most serious risks include severe hypercalcemia, which can cause confusion, cardiac arrhythmias, and renal impairment, as well as hypervitaminosis D leading to tissue calcification. Rarely, allergic reactions such as rash, swelling, or anaphylaxis may occur. Patients should seek medical attention if they experience any of these symptoms.

Individuals with known hypersensitivity to colecalciferol, calcium carbonate, or any excipients should avoid the product. It is also contraindicated in patients with hypercalcemia, severe renal disease, sarcoidosis, or other granulomatous disorders that predispose to excess vitamin D activation. Consultation with a health‑care provider is essential before starting the supplement.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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