Product image of Natemille (Colecalciferol, Calcium Carbonate) supplied by GNH India

Natemille

Active Ingredient:
Colecalciferol, Calcium Carbonate
Origin:
EU

Natemille (Colecalciferol, Calcium Carbonate)

Colecalciferol, the active ingredient in Natemille, is a vitamin D and calcium supplement presented as an oral dosage form for oral use. Together with calcium carbonate, it provides vitamin D3 and calcium to support calcium absorption and bone mineralisation, helping to prevent deficiency states in adults and older individuals.

GNH India supplies Natemille as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The product complies with EU quality standards and is distributed under strict Good Distribution Practice guidelines.

Manufacturer / TM Owner

Italfarmaco S.P.A

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Natemille is a vitamin D and calcium supplement that acts on mineral metabolism and bone health.

  • Calcium deficiency: helps restore adequate calcium levels and reduce related symptoms.
  • Vitamin D deficiency: raises serum 25‑hydroxyvitamin D concentrations to normal ranges.
  • Bone health support: contributes to bone mineralisation and reduces risk of osteopenia.
  • Osteoporosis prevention: provides nutrients that aid in maintaining bone density in at‑risk populations.

How It Works

  • Colecalciferol (vitamin D3) is metabolised in the liver and kidneys to the active hormone calcitriol, which binds to nuclear vitamin D receptors and up‑regulates intestinal calcium‑binding proteins, enhancing calcium absorption. Calcium carbonate supplies elemental calcium that is absorbed in the gut. The combined effect increases serum calcium and phosphate, promoting hydroxyapatite formation and bone mineralisation.

Side Effects

Adverse reactions may occur with oral vitamin D and calcium supplementation.

Common Side Effects

  • Hypercalcaemia: elevated blood calcium levels causing fatigue or mild nausea.
  • Gastrointestinal upset: abdominal discomfort, bloating or flatulence.
  • Constipation: reduced bowel movements, especially with calcium carbonate.
  • Nausea: feeling of sickness after ingestion.
  • Headache: mild to moderate head pain.
  • Metallic taste: transient alteration in taste perception.

Serious or Rare Side Effects

  • Severe hypercalcaemia: can lead to kidney stones, cardiac arrhythmia or confusion.
  • Hypervitaminosis D: excessive vitamin D causing tissue calcification.
  • Allergic reaction: rash, itching, swelling or difficulty breathing.
  • Acute pancreatitis: rare inflammation of the pancreas.
  • Renal impairment: worsening kidney function in susceptible individuals.
  • Calcification of soft tissues: abnormal calcium deposition in organs.

Precautions & Warnings

Natemille should be used with consideration of individual health status and monitoring requirements.

  • Baseline assessment: evaluate serum calcium and vitamin D levels before initiating therapy.
  • Renal function: use cautiously in patients with impaired kidney function.
  • Hypercalcaemia: avoid in individuals with known high calcium levels.
  • Sarcoidosis or granulomatous disease: contraindicated due to risk of excess vitamin D activation.
  • Pregnancy and lactation: safety not established; consult a healthcare professional.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Natemille may interact with other medicines that affect calcium or vitamin D metabolism.

Major Interactions (Avoid)

  • Thiazide diuretics: increase risk of hypercalcaemia.
  • Lithium: may potentiate hypercalcaemia.
  • High‑dose vitamin A: synergistic toxicity leading to hypervitaminosis.
  • Antacids containing aluminium or magnesium: reduce calcium absorption.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: may increase calcium loss, requiring monitoring.
  • Bisphosphonates: concurrent use may affect bone turnover markers.
  • Corticosteroids: can reduce calcium absorption, necessitating dose adjustment.
  • Anticonvulsants (e.g., phenytoin): may accelerate vitamin D metabolism.
  • ACE inhibitors: monitor blood pressure and electrolyte balance.

Frequently Asked Questions

Natemille is a nutritional supplement that provides vitamin D3 (colecalciferol) and calcium carbonate. It is used to prevent or correct calcium and vitamin D deficiencies, support normal bone mineralisation, and help reduce the risk of osteoporosis in adults and older individuals.

Colecalciferol is vitamin D3, which is converted in the liver and kidneys to the active hormone calcitriol. Calcitriol binds to vitamin D receptors in the intestine, increasing the synthesis of calcium‑binding proteins and thereby enhancing calcium absorption from the gut. This supports bone mineralisation and calcium homeostasis.

The appropriate dose of Natemille is determined by the prescribing healthcare professional based on the patient’s age, clinical condition, laboratory values and local guidelines. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for Natemille in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential benefits and risks with their healthcare provider before using the product.

To order Natemille, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Natemille combines colecalciferol and calcium carbonate in a single oral formulation, offering both vitamin D3 and a readily absorbable calcium source. Compared with products that contain only vitamin D or calcium, Natemille provides a synergistic effect on calcium absorption and bone health, potentially reducing the need for multiple supplements.

Natemille should be stored at ambient temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

Natemille is taken orally, usually with water. It may be taken with or without food, but taking it with a meal that contains some fat can improve the absorption of vitamin D3. Patients should follow the dosing instructions provided by their prescriber.

The most serious risks include severe hypercalcaemia, which can cause kidney stones, cardiac arrhythmias, or neurological symptoms, and hypervitaminosis D leading to soft‑tissue calcification. Any signs of excessive calcium, such as persistent nausea, vomiting, confusion or muscle weakness, should prompt immediate medical evaluation.

Natemille should be avoided in individuals with known hypercalcaemia, severe renal impairment, sarcoidosis or other granulomatous diseases, and in patients who are hypersensitive to any of its ingredients. Pregnant or breastfeeding women should only use it after consulting a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Colecalciferol, Calcium Carbonate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT