Product image of Natrijev Klorid Hztm (Sodium Chloride) supplied by GNH India

Natrijev Klorid Hztm

Active Ingredient:
Sodium Chloride
Origin:
EU

Natrijev Klorid Hztm (Sodium Chloride)

Sodium chloride, the active ingredient in Natrijev Klorid Hztm, is an electrolyte solution presented as an injection solution for intravenous use. It restores extracellular sodium concentration and osmolarity, aiding fluid balance and electrolyte homeostasis in patients who need fluid replacement or electrolyte replenishment.

GNH India supplies Natrijev Klorid Hztm as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies, clinics and other healthcare facilities worldwide.

Manufacturer / TM Owner

Hrvatski Zavod Za Transfuzijsku Medicinu

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Indications & Clinical Uses

Natrijev Klorid Hztm is an intravenous electrolyte solution used in conditions where fluid and sodium balance must be restored.

  • Fluid replacement: restores intravascular volume and supports circulatory stability.
  • Electrolyte replenishment: corrects sodium deficits and normalizes plasma osmolarity.
  • Treatment of dehydration: provides rapid rehydration in acute fluid loss.
  • Management of hypovolemia: increases circulating blood volume to improve tissue perfusion.

How It Works

  • Sodium chloride injection delivers chloride and sodium ions directly into the bloodstream, increasing extracellular sodium concentration and plasma osmolarity. This osmotic shift draws water into the intravascular compartment, expanding blood volume and correcting hyponatremia. The restored electrolyte balance supports cellular function, nerve conduction, and muscle activity, while the increased volume improves cardiac output and tissue perfusion.

Side Effects

Adverse reactions may occur with intravenous sodium chloride administration.

Common Side Effects

  • Hypernatremia: elevated serum sodium levels causing thirst and confusion.
  • Fluid overload: signs include peripheral edema and shortness of breath.
  • Local irritation: pain, erythema, or phlebitis at the infusion site.
  • Nausea or mild headache.

Serious or Rare Side Effects

  • Severe hypernatremia leading to seizures or coma.
  • Pulmonary edema with respiratory distress.
  • Anaphylactic reaction: rare but may present with hives, bronchospasm, or hypotension.

Precautions & Warnings

When using Natrijev Klorid Hztm, clinicians should consider several safety measures.

  • Assess electrolyte status: check serum sodium before and during therapy.
  • Monitor fluid balance: record input and output to avoid overload.
  • Adjust infusion rate: tailor speed to patient condition and tolerance.
  • Use aseptic technique: prevent contamination of the injection solution.
  • Store at below 25°C: keep in the original container, protect from light and moisture.

Avoid Interactions

Sodium chloride can interact with other medications that affect fluid or electrolyte balance.

Major Interactions (Avoid)

  • Lithium therapy: may increase lithium serum concentrations.
  • Loop diuretics: can exacerbate sodium loss and electrolyte disturbances.
  • Corticosteroids: may enhance sodium retention and raise blood pressure.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: may reduce their effectiveness due to volume expansion.
  • Cardiac glycosides: require monitoring of serum electrolytes to avoid toxicity.
  • Contrast media: concurrent use can increase risk of hypernatremia.

Frequently Asked Questions

Natrijev Klorid Hztm is an intravenous sodium chloride solution used to replace lost fluids, restore sodium balance, and treat conditions such as dehydration, hypovolemia, and electrolyte disturbances. It provides rapid rehydration and helps maintain circulatory stability in hospital or clinical settings.

Sodium chloride delivers sodium and chloride ions directly into the bloodstream, raising extracellular sodium concentration and plasma osmolarity. This osmotic effect pulls water into the vascular space, expanding blood volume, correcting hyponatremia, and supporting normal cellular and nerve function.

The appropriate dose of Natrijev Klorid Hztm is determined by the prescribing clinician based on the patient’s age, weight, clinical condition, and laboratory values. Healthcare professionals calculate the required volume and concentration to achieve the desired fluid and electrolyte goals.

Sodium chloride is a naturally occurring electrolyte, and its use in pregnancy or breastfeeding is generally considered safe when medically indicated. However, the prescriber should evaluate the individual risk‑benefit profile, especially in cases of underlying renal or cardiovascular disease.

To order Natrijev Klorid Hztm, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Natrijev Klorid Hztm is comparable to other sterile sodium chloride injection solutions in terms of composition and clinical use. Differences may lie in manufacturing standards, packaging, and regulatory approvals. Clinicians choose a product based on quality certifications, supply reliability, and compatibility with their institution’s protocols.

The product should be stored at temperatures below 25 °C, protected from direct sunlight, moisture, and freezing. Keep the vial in its original packaging until use and inspect for particulate matter or discoloration before administration.

Natrijev Klorid Hztm is administered intravenously by slow infusion or bolus, depending on the clinical situation. The infusion rate is set by the healthcare provider, and the solution is typically delivered through a sterile IV line using aseptic technique.

Serious risks include severe hypernatremia, pulmonary edema, and rare anaphylactic reactions. These events require immediate medical attention and close monitoring of serum electrolytes, fluid status, and patient symptoms during and after infusion.

Patients with known hypersensitivity to sodium chloride solutions, uncontrolled hypertension, severe heart failure, or those at risk of fluid overload should be evaluated carefully before receiving Natrijev Klorid Hztm. The prescriber must assess contraindications and adjust therapy accordingly.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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