Product image of Natrio Jodidas [131i] Ge Healthcare (Sodium Iodide (131i)) supplied by GNH India

Natrio Jodidas [131i] Ge Healthcare

Active Ingredient:
Sodium Iodide (131i)
Origin:
EU

Natrio Jodidas [131i] Ge Healthcare (Sodium Iodide (131i))

Sodium Iodide, the active ingredient in Natrio Jodidas [131i] Ge Healthcare, is a radioactive iodine presented as a diagnostic radiopharmaceutical for oral use. It is selectively taken up by thyroid tissue, enabling imaging and functional assessment of the gland in patients with suspected thyroid disorders.

GNH India supplies Natrio Jodidas [131i] Ge Healthcare as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and clinics worldwide. The company adheres to stringent quality standards and provides regulatory support for cross‑border distribution.

Manufacturer / TM Owner

Ge Healthcare Buchler Gmbh & Co. Kg

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Indications & Clinical Uses

Natrio Jodidas (Sodium Iodide) is used in nuclear medicine for diagnostic evaluation of thyroid‑related conditions.

  • Thyroid imaging: enables visualization of thyroid tissue to assess anatomy and function.
  • Hyperthyroidism assessment: helps determine the functional activity of overactive thyroid tissue.
  • Thyroid nodule evaluation: assists in distinguishing benign from malignant nodules through uptake patterns.

How It Works

  • Sodium Iodide-131 is a radioactive isotope that mimics natural iodine and is actively transported into thyroid follicular cells via the sodium‑iodide symporter. Once concentrated in the gland, the emitted beta particles provide localized radiation that can be detected by gamma cameras, allowing precise imaging of thyroid tissue distribution and activity.

Side Effects

Adverse reactions may occur following oral administration of radioactive iodine.

Common Side Effects

  • Nausea or vomiting.
  • Metallic taste in the mouth.
  • Mild abdominal discomfort.
  • Transient increase in thyroid hormone levels.
  • Temporary sore throat.
  • Mild skin erythema at the site of radiation exposure.

Serious or Rare Side Effects

  • Radiation thyroiditis causing painful swelling.
  • Acute hypothyroidism requiring hormone replacement.
  • Bone marrow suppression leading to leukopenia.
  • Allergic reactions such as rash or urticaria.
  • Severe radiation burns if mishandled.
  • Long‑term risk of secondary malignancies (very rare).

Precautions & Warnings

Use of Natrio Jodidas requires careful consideration of patient factors and handling procedures.

  • Pregnancy: avoid unless clearly indicated, as fetal thyroid can be affected.
  • Breastfeeding: discontinue breastfeeding for an appropriate period after administration.
  • Thyroid function: assess baseline thyroid status before use.
  • Concomitant iodine exposure: avoid iodine‑containing contrast agents or supplements for several days prior.
  • Renal impairment: monitor because excretion is renal.
  • Store at ambient temperature: keep below 25°C in the original container, protect from moisture and light.

Avoid Interactions

Radioactive iodine can interact with several medications and substances that affect iodine uptake.

Major Interactions (Avoid)

  • Antithyroid drugs (e.g., methimazole, propylthiouracil): markedly reduce iodine uptake.
  • Iodine‑containing contrast agents: block thyroid uptake for up to several weeks.
  • High‑dose potassium iodide supplements: competitively inhibit tracer accumulation.

Moderate Interactions (Monitor Closely)

  • Thyroid hormone replacement therapy: may alter diagnostic interpretation.
  • Lithium therapy: can increase iodine retention in the thyroid.
  • Amiodarone: high iodine load may affect imaging results.
  • Diuretics: may influence renal clearance of the isotope.

Frequently Asked Questions

Natrio Jodidas contains Sodium Iodide‑131 and is used as a diagnostic radiopharmaceutical to image the thyroid gland. It helps clinicians assess thyroid anatomy, function, and the presence of nodules or hyperactive tissue during nuclear medicine scans.

Sodium Iodide‑131 mimics natural iodine and is taken up by thyroid cells via the sodium‑iodide symporter. The radioactive decay emits gamma photons that are captured by imaging equipment, providing a visual map of iodine uptake and thyroid activity.

The dose of Natrio Jodidas is determined by the prescribing physician based on the specific diagnostic protocol, patient weight, and clinical indication. The prescriber calculates the appropriate activity (in megabecquerels) to achieve optimal imaging quality while minimizing radiation exposure.

Use of radioactive iodine is generally contraindicated in pregnancy because the fetal thyroid can absorb the isotope, potentially causing damage. Breastfeeding mothers should discontinue nursing for a period recommended by the treating physician to avoid infant exposure.

To order Natrio Jodidas, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Natrio Jodidas (Sodium Iodide‑131) offers both imaging and a therapeutic radiation component, unlike non‑radioactive agents such as technetium‑99m pertechnetate, which provide only diagnostic information. The iodine‑131 tracer provides longer‑lasting radiation suitable for certain functional studies, but it also requires stricter radiation safety measures.

Store Natrio Jodidas at ambient temperature, preferably below 25 °C, in its original sealed container. Protect the product from moisture, direct sunlight, and physical damage. Follow all local regulations for handling radioactive materials, including using appropriate shielding and labeling.

Natrio Jodidas is administered orally as a single dose. The patient swallows the prescribed amount of the radiopharmaceutical, after which imaging is performed at a predetermined time interval to allow adequate thyroid uptake of the isotope.

Serious risks include radiation thyroiditis, acute hypothyroidism, bone marrow suppression, and, rarely, secondary malignancies due to radiation exposure. Patients should be monitored for signs of severe thyroid inflammation, abnormal blood counts, and any unexpected systemic symptoms.

Natrio Jodidas should be avoided in pregnant women, nursing mothers, patients with severe iodine allergy, and individuals who have recently received iodine‑containing contrast agents or high‑dose potassium iodide. It is also contraindicated in patients with uncontrolled hyperthyroidism unless specifically indicated by a specialist.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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