Natrium Bicarbonaat B. Braun Melsungen (Sodium Hydrogen Carbonate)

Sodium bicarbonate dissociates into sodium and bicarbonate ions after intravenous administration. The bicarbonate ions bind excess hydrogen ions, forming carbonic acid, which is rapidly converted to water and carbon dioxide. This buffering reduces hydrogen ion concentration, raising blood pH and restoring acid‑base balance.

The dose is individualized by the prescribing clinician based on the patient’s acid‑base status, serum electrolyte levels, underlying condition, and response to therapy. Dosage calculations consider factors such as body weight, severity of acidosis, and concurrent medical therapies.

Safety data for sodium bicarbonate injection in pregnancy and lactation are limited. It should only be used when clearly indicated and the potential benefits outweigh any possible risks. Clinicians should evaluate maternal and fetal conditions before prescribing.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and necessary import documentation.

Sodium bicarbonate is a rapid‑acting, directly administered source of bicarbonate ions, whereas other agents such as tromethamine (THAM) act indirectly or have different electrolyte profiles. Sodium bicarbonate is widely used because of its familiarity, cost‑effectiveness, and immediate buffering capacity, though alternative agents may be chosen in specific clinical scenarios.

The solution for injection should be stored at 2‑8 °C, kept refrigerated, protected from light, and must not be frozen or shaken. Maintaining the cold chain preserves stability and potency until the product is administered.

It is administered intravenously as a sterile solution. The infusion rate and volume are determined by the prescriber, often based on the severity of acidosis, target pH correction, and patient tolerance. Administration should follow aseptic technique and institutional protocols.

Serious risks include severe metabolic alkalosis, hypernatremia, cardiac arrhythmias due to rapid electrolyte shifts, pulmonary edema in patients with compromised cardiac function, and rare anaphylactoid reactions. Continuous monitoring of blood gases, electrolytes, and hemodynamic status is essential during therapy.

Patients with known hypersensitivity to sodium bicarbonate, uncontrolled severe hypernatremia, uncompensated metabolic alkalosis, or those in whom rapid fluid overload would be hazardous (e.g., severe heart failure) should not receive this product unless benefits clearly outweigh risks.