Product image of Natrium Chloride Aguettant (Sodium Chloride) supplied by GNH India

Natrium Chloride Aguettant

Active Ingredient:
Sodium Chloride
Origin:
EU

Natrium Chloride Aguettant (Sodium Chloride)

Sodium Chloride, the active ingredient in Natrium Chloride Aguettant, is an electrolyte presented as a solution for injection for intravenous use. It helps replace fluid and electrolyte losses in patients who need volume expansion or correction of hyponatremia.
GNH India supplies Natrium Chloride Aguettant as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Laboratoire Aguettant

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Indications & Clinical Uses

Natrium Chloride Aguettant is used in clinical situations that require rapid restoration of extracellular fluid and electrolyte balance.

  • Hyponatremia: restores normal serum sodium levels in patients with low sodium concentrations.
  • Hypovolemia: expands intravascular volume to improve blood pressure and tissue perfusion.
  • Peri‑operative fluid management: maintains electrolyte balance and volume status during surgery.
  • Fluid and electrolyte replacement: corrects deficits caused by burns, diarrhea, or excessive sweating.

How It Works

  • Sodium Chloride provides sodium (Na⁺) and chloride (Cl⁻) ions that are readily absorbed into the extracellular compartment after intravenous administration. The added ions increase osmotic pressure, drawing water into the vascular space, thereby expanding plasma volume and correcting electrolyte imbalances. This restores normal cellular function and supports hemodynamic stability.

Side Effects

Adverse reactions may occur with any intravenous electrolyte solution.

Common Side Effects

  • Hypernatremia: elevated serum sodium if administered excessively.
  • Fluid overload: signs of edema or pulmonary congestion.
  • Phlebitis: inflammation at the infusion site.
  • Injection site pain or irritation.
  • Hypertension: transient increase in blood pressure.
  • Electrolyte imbalance: shifts in potassium or calcium levels.

Serious or Rare Side Effects

  • Severe hypernatremia leading to neurologic symptoms.
  • Pulmonary edema with respiratory distress.
  • Anaphylactic or severe allergic reaction.
  • Cardiac arrhythmias due to rapid electrolyte shifts.
  • Metabolic acidosis in extreme cases.

Precautions & Warnings

When using Natrium Chloride Aguettant, clinicians should consider several safety measures.

  • Assess baseline serum electrolytes: verify sodium and chloride levels before infusion.
  • Monitor fluid balance: track input, output, and weight to avoid overload.
  • Adjust infusion rate: use controlled rates, especially in patients with cardiac or renal impairment.
  • Avoid rapid large-volume bolus: limit to recommended clinical guidelines.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Potential drug interactions may modify the safety or efficacy of Natrium Chloride Aguettant.

Major Interactions (Avoid)

  • Concurrent hypertonic saline solutions: may cause severe hypernatremia.
  • Potassium chloride infusions given simultaneously: risk of hyperkalemia and precipitation.
  • Diuretics that cause rapid sodium loss: may exacerbate electrolyte disturbances.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may enhance potassium retention.
  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): can affect renal sodium handling.
  • Corticosteroids: may increase sodium retention and fluid volume.

Frequently Asked Questions

Natrium Chloride Aguettant is an intravenous sodium chloride solution used to replace lost fluids and electrolytes, correct hyponatremia, treat hypovolemia, and maintain electrolyte balance during surgery or other medical procedures.

The solution delivers sodium and chloride ions directly into the bloodstream, increasing extracellular osmolarity. This draws water into the vascular compartment, expanding plasma volume and restoring normal serum sodium and chloride concentrations.

The prescribed dose is determined by the treating physician based on the patient’s clinical condition, serum electrolyte levels, and required volume replacement. Dosage is individualized and not fixed.

Safety data for use in pregnancy or lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Natrium Chloride Aguettant provides a pure sodium chloride formulation, whereas some alternatives contain additional electrolytes such as potassium or calcium. The choice depends on the specific electrolyte deficits and clinical goals defined by the prescriber.

The solution should be stored at 2‑8 °C, protected from light, and must not be frozen or shaken. Keep the vial in its original packaging until use to maintain sterility.

It is administered intravenously, typically via a controlled infusion pump or gravity drip, following the rate and volume ordered by the prescriber. Administration sets must be sterile and compatible with the solution.

Serious risks include severe hypernatremia, pulmonary edema, anaphylactic reactions, and cardiac arrhythmias caused by rapid electrolyte shifts. Immediate medical attention is required if any of these occur.

Patients with known hypersensitivity to sodium chloride solutions, uncontrolled heart failure, severe renal impairment, or those at risk of fluid overload should avoid this product unless closely monitored by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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