Product image of Natriumbikarbonat Evolan (Sodium Hydrogen Carbonate) supplied by GNH India

Natriumbikarbonat Evolan

Active Ingredient:
Sodium Hydrogen Carbonate
Origin:
EU

Natriumbikarbonat Evolan (Sodium Hydrogen Carbonate)

Sodium hydrogen carbonate, the active ingredient in Natriumbikarbonat Evolan, is an antacid presented as an oral preparation for oral use. It is employed to relieve acid indigestion, heartburn and to correct metabolic acidosis in appropriate patients.

GNH India supplies Natriumbikarbonat Evolan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution. Customers benefit from comprehensive regulatory support, batch traceability, and on‑time delivery across multiple continents.

Manufacturer / TM Owner

Evolan Pharma Ab

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Indications & Clinical Uses

Natriumbikarbonat Evolan, an antacid, is used to manage conditions related to excess gastric acid and systemic acid‑base disturbances.

  • Acid indigestion: provides rapid relief of discomfort by neutralizing stomach acid.
  • Heartburn: reduces burning sensation in the esophagus through acid neutralization.
  • Metabolic acidosis: supplies systemic alkali to help correct low blood pH in appropriate clinical settings.

How It Works

  • After oral administration, sodium hydrogen carbonate dissociates into sodium and bicarbonate ions. The bicarbonate reacts with hydrogen ions in gastric juice, forming carbonic acid, which quickly decomposes to carbon dioxide and water, thereby raising gastric pH. In the systemic circulation, the bicarbonate ion acts as a buffer, contributing to the extracellular alkaline reserve and assisting in the correction of metabolic acidosis.

Side Effects

Sodium hydrogen carbonate may cause several adverse reactions, most of which are mild and related to its alkalinizing properties.

Common Side Effects

  • Belching: excess gas leading to frequent burping.
  • Flatulence: increased intestinal gas causing abdominal discomfort.
  • Nausea: mild stomach upset after ingestion.

Serious or Rare Side Effects

  • Metabolic alkalosis: excessive rise in blood pH that can cause confusion or muscle twitching.
  • Hypernatremia: elevated sodium levels that may result in hypertension or edema.
  • Severe electrolyte imbalance: dangerous shifts in potassium or calcium requiring medical attention.

Precautions & Warnings

Before using Natriumbikarbonat Evolan, consider the following precautions to ensure safe and effective therapy.

  • Assess renal function: impaired kidneys may reduce bicarbonate excretion and increase risk of alkalosis.
  • Monitor electrolytes: watch for sodium, potassium and calcium disturbances during prolonged use.
  • Use cautiously in hypertension: high sodium load can exacerbate blood pressure.
  • Avoid excessive dosing: large amounts may lead to metabolic alkalosis.
  • Store at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Natriumbikarbonat Evolan can affect the absorption or activity of several medicines; interactions should be reviewed.

Major Interactions (Avoid)

  • Aspirin and other NSAIDs: concurrent use may increase risk of renal toxicity.
  • Warfarin: bicarbonate may alter anticoagulant effect, affecting INR stability.
  • Lithium: sodium load can raise lithium concentrations, risking toxicity.

Moderate Interactions (Monitor Closely)

  • Tetracycline antibiotics: reduced absorption due to increased gastric pH.
  • Digoxin: altered serum levels may occur, requiring monitoring.
  • Diuretics: enhanced potassium loss may necessitate electrolyte checks.

Frequently Asked Questions

Natriumbikarbonat Evolan contains sodium hydrogen carbonate, an antacid that neutralizes excess stomach acid and provides systemic alkali. It is commonly employed to relieve acid indigestion and heartburn, and in clinical settings it may be used to correct metabolic acidosis when directed by a healthcare professional.

After oral intake, sodium hydrogen carbonate dissociates into sodium and bicarbonate ions. The bicarbonate reacts with hydrogen ions in the stomach, forming carbonic acid, which quickly breaks down into carbon dioxide and water, raising gastric pH. Systemically, the bicarbonate ion acts as a buffer, increasing the extracellular alkaline reserve and helping to correct low blood pH in metabolic acidosis.

The appropriate dose of Natriumbikarbonat Evolan is determined by the prescribing clinician based on the individual’s condition, age, renal function and other medications. Patients should follow the specific instructions on the prescription label and consult their healthcare provider for any dosage adjustments.

Safety data for sodium hydrogen carbonate in pregnancy and lactation are limited. It should only be used if the potential benefit outweighs any possible risk to the fetus or infant, and under the guidance of a qualified healthcare professional. Pregnant or nursing women should discuss use with their doctor.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Sodium hydrogen carbonate offers rapid neutralization of gastric acid and provides systemic alkalinity, which distinguishes it from calcium‑based or aluminum‑based antacids that act locally. Compared with proton‑pump inhibitors, it works faster but for short‑term relief. Choice of therapy depends on the clinical situation and physician recommendation.

The product should be stored at room temperature, below 25 °C, in its original packaging. Protect it from moisture, excessive heat and direct sunlight to maintain stability. Do not store in a refrigerator or freezer unless the label specifically indicates otherwise.

Natriumbikarbonat Evolan is taken orally, typically as a tablet, powder or liquid that is dissolved in water before ingestion, as directed by the prescribing clinician. It should be swallowed with a full glass of water and not chewed unless the formulation specifies otherwise.

The most serious risks include metabolic alkalosis, hypernatremia and severe electrolyte disturbances such as hypokalemia. These conditions can lead to confusion, muscle twitching, hypertension, edema or cardiac arrhythmias and require immediate medical attention. Patients with kidney disease, heart failure or uncontrolled hypertension are at higher risk.

Individuals with known hypersensitivity to sodium bicarbonate, severe renal impairment, uncontrolled hypertension, or those on a sodium‑restricted diet should avoid Natriumbikarbonat Evolan unless a healthcare professional determines it is safe. It is also contraindicated in patients with metabolic alkalosis or those receiving high‑dose sodium‑containing medications without supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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