Product image of Natriumchlorid Dirinco (Sodium Chloride) supplied by GNH India

Natriumchlorid Dirinco

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumchlorid Dirinco (Sodium Chloride)

Sodium chloride, the active ingredient in Natriumchlorid Dirinco, is an electrolyte presented as a solution for injection for intravenous use. It is employed to treat hypovolemia, electrolyte imbalance and hyponatremia in patients who require rapid restoration of extracellular sodium and chloride levels.
GNH India supplies Natriumchlorid Dirinco as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Dirinco Bv

1
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Indications & Clinical Uses

Natriumchlorid Dirinco is an intravenous electrolyte solution used to correct fluid and electrolyte disturbances.

  • Hypovolemia: restores circulating blood volume and improves tissue perfusion.
  • Electrolyte imbalance: corrects deficits of sodium and chloride in the extracellular space.
  • Hyponatremia: raises serum sodium concentration to safe levels.

How It Works

  • Sodium chloride solution delivers Na+ and Cl‑ ions directly into the bloodstream, increasing extracellular osmolarity and expanding intravascular volume. This rapid infusion restores normal plasma sodium and chloride concentrations, supporting cellular function and hemodynamic stability.

Side Effects

Adverse reactions may occur with any intravenous therapy.

Common Side Effects

  • Injection site pain: mild discomfort at the infusion site.
  • Hypernatremia: elevated serum sodium if administered in excess.
  • Fluid overload: signs of excess volume such as peripheral edema.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response requiring immediate treatment.
  • Pulmonary edema: accumulation of fluid in the lungs due to volume overload.
  • Cardiac arrhythmia: abnormal heart rhythm associated with electrolyte disturbances.

Precautions & Warnings

Use of Natriumchlorid Dirinco requires careful clinical assessment.

  • Assess fluid status: evaluate volume needs before infusion.
  • Monitor electrolytes: check serum sodium and chloride during therapy.
  • Adjust rate in cardiac failure: reduce infusion speed to avoid overload.
  • Use aseptic technique: prevent contamination of the solution.
  • Contraindicate in severe hypernatremia: avoid if serum sodium is already markedly elevated.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Sodium chloride may interact with other agents that affect fluid and electrolyte balance.

Major Interactions (Avoid)

  • Hypertonic saline: concurrent use can cause severe hypernatremia.
  • Loop diuretics: may lead to rapid shifts in sodium and fluid status.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: increase risk of fluid retention.
  • NSAIDs: may impair renal handling of sodium.
  • Blood products: combined volume may precipitate overload.

Frequently Asked Questions

Natriumchlorid Dirinco is an intravenous sodium chloride solution used to treat hypovolemia, correct electrolyte imbalances, and manage hyponatremia. It provides rapid restoration of extracellular sodium and chloride, supporting blood volume and normal cellular function in patients who need fluid replacement.

When infused, sodium chloride dissociates into sodium (Na+) and chloride (Cl‑) ions. These ions increase extracellular osmolarity, expand intravascular volume, and raise serum sodium levels, thereby normalising fluid distribution and supporting cardiovascular stability.

The dose is determined by the prescribing clinician based on the patient’s fluid status, electrolyte levels, and clinical condition. Dosage may be expressed in millilitres or milliequivalents per kilogram and is adjusted according to ongoing monitoring.

Safety data in pregnancy and lactation are limited. Because sodium chloride is a naturally occurring electrolyte, it is generally considered compatible when clinically indicated, but the prescriber should weigh potential benefits against any unknown risks.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and required import documentation.

Natriumchlorid Dirinco is a standard isotonic sodium chloride solution similar to other 0.9% NaCl injections. Its distinguishing features are EU‑origin manufacturing, compliance with Good Distribution Practice, and availability through GNH India’s global supply network.

Store the solution at 2‑8 °C in a refrigerator, protect it from light, and do not freeze or shake the container. Keep the vial in its original packaging until use to maintain sterility.

The product is given by intravenous infusion using aseptic technique. It can be administered as a bolus or continuous infusion, depending on the clinical situation and the prescriber’s instructions.

Serious risks include severe hypernatremia, anaphylactic reactions, pulmonary edema, and cardiac arrhythmias. Immediate medical attention is required if signs of allergic reaction, respiratory distress, or abnormal heart rhythm develop.

Patients with known hypersensitivity to sodium chloride solutions, those with severe hypernatremia, or individuals at high risk of fluid overload (e.g., uncontrolled heart failure) should avoid this product unless a prescriber determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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