Product image of Natriumchlorid Fresenius (Sodium Chloride) supplied by GNH India

Natriumchlorid Fresenius

Active Ingredient:
Sodium Chloride
Origin:
EU

Natriumchlorid Fresenius (Sodium Chloride)

Sodium Chloride, the active ingredient in Natriumchlorid Fresenius, is an electrolyte presented as an injection solution for intravenous use. It restores extracellular sodium and chloride concentrations and expands plasma volume, aiding fluid replacement and electrolyte balance in patients with hypovolemia or hyponatremia.

GNH India supplies Natriumchlorid Fresenius as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and oncology centres worldwide.

Manufacturer / TM Owner

Fresenius Kabi Austria Gmbh

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Indications & Clinical Uses

Natriumchlorid Fresenius, an intravenous sodium chloride solution, is used in fluid and electrolyte replacement therapy.

  • Fluid replacement: restores intravascular volume in patients with blood loss or dehydration.
  • Electrolyte replenishment: corrects sodium and chloride deficits.
  • Hyponatremia: raises low serum sodium levels.
  • Hypovolemia: expands plasma volume to improve circulatory stability.

How It Works

  • Sodium chloride provides Na+ and Cl- ions that increase extracellular osmolarity, drawing water into the vascular compartment. This raises plasma volume and corrects electrolyte imbalances, supporting normal cellular function and hemodynamic stability.

Side Effects

Adverse reactions may occur with intravenous sodium chloride administration.

Common Side Effects

  • Injection site pain: discomfort at the infusion site.
  • Phlebitis: inflammation of the vein.
  • Hypernatremia: elevated serum sodium.
  • Hyperchloremia: elevated serum chloride.
  • Fluid overload: excess extracellular fluid.
  • Electrolyte imbalance: disturbances in other electrolytes.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response.
  • Severe hypervolemia: dangerous fluid excess.
  • Metabolic acidosis: significant pH shift.
  • Cardiac arrhythmia: abnormal heart rhythm.

Precautions & Warnings

When using Natriumchlorid Fresenius, clinicians should observe several safety measures.

  • Monitor serum electrolytes: check sodium and chloride levels regularly.
  • Assess fluid status: avoid use in patients with existing fluid overload.
  • Use caution in renal impairment: adjust volume as needed.
  • Avoid rapid infusion: follow recommended infusion rates.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Intravenous sodium chloride can interact with other therapies; awareness of major and moderate interactions helps ensure safe use.

Major Interactions (Avoid)

  • Concomitant hypertonic saline: risk of severe hypernatremia.
  • Loop diuretics: may exacerbate electrolyte shifts.

Moderate Interactions (Monitor Closely)

  • Corticosteroids: may affect fluid balance.
  • Vasopressors: may require dose adjustments.
  • Anticoagulants: volume changes can influence bleeding risk.

Frequently Asked Questions

Natriumchlorid Fresenius is an intravenous sodium chloride solution used to replace lost fluids, replenish sodium and chloride electrolytes, and treat conditions such as hypovolemia and hyponatremia by expanding plasma volume and correcting electrolyte imbalances.

Sodium chloride delivers Na+ and Cl- ions that increase extracellular osmolarity, drawing water into the bloodstream. This raises plasma volume and restores normal sodium and chloride concentrations, supporting fluid balance and cellular function.

The dose of Natriumchlorid Fresenius is determined by the prescribing clinician based on the patient’s clinical condition, electrolyte levels, and fluid requirements. Healthcare professionals calculate the appropriate volume and concentration for each individual case.

Safety data for Natriumchlorid Fresenius in pregnancy or lactation are limited. Use only if the potential benefit justifies any potential risk to the fetus or infant, and decisions should be made by a qualified healthcare provider.

To order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Natriumchlorid Fresenius provides a standard isotonic sodium chloride formulation, similar to other 0.9% saline solutions. Compared with balanced electrolyte solutions, it contains only Na+ and Cl‑, making it suitable when a simple chloride‑based replacement is required, but it lacks additional buffers such as lactate or acetate.

The product should be stored at 2‑8 °C, kept refrigerated, protected from light, and must not be frozen or shaken. Maintain the original packaging until use to preserve sterility and solution integrity.

It is administered intravenously by slow infusion through a suitable vein or central line. The infusion rate and total volume are set by the prescriber according to the patient’s fluid and electrolyte needs, following institutional protocols.

Serious risks include anaphylactic reactions, severe hypervolemia, metabolic acidosis, and cardiac arrhythmias. These events are rare but require immediate medical attention if they occur.

Patients with known hypersensitivity to sodium chloride, those with uncontrolled fluid overload, severe renal impairment without appropriate monitoring, or individuals for whom rapid infusion could cause cardiovascular compromise should not receive this product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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